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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
114 Results for "
Zanthoxylum coco Gillies ex Hook.
" in MedChemExpress (MCE) Product Catalog:
Products (114)
114 Results for "Zanthoxylum coco Gillies ex Hook." in MCE Product Catalog:
6
Category:
Cardiovascular Disease Uncaria rhynchophylla (Miq.) Miq. ex Havil. Alkaloids Rubiaceae Plants Disease Research Fields Indole Alkaloids
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4
4
4 Cited Publications
Cat. No.: HY-N0498
CAS No.: 13063-04-2
4
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2
1
1 Cited Publications
Cat. No.: HY-N6824
CAS No.: 97465-69-5
Category:
Zanthoxylum bungeanum Maxim. Alkaloids Other Alkaloids Other Diseases Rutaceae Plants Disease Research Fields
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1
Category:
Infection Flavonols Flavonoids Rutaceae Phenols Polyphenols Plants Disease Research Fields Zanthoxylum armatum DC.
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1
1 Cited Publications
Cat. No.: HY-N2411
CAS No.: 60314-89-8
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Category:
Infection Zanthoxylum bungeanum Maxim. Monophenols Rutaceae Phenols Plants Disease Research Fields Zanthoxylum simulans Hance
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Cat. No.: HY-N5037
CAS No.: 109008-27-7
Category:
Cardiovascular Disease Aquifoliaceae Triterpenes Terpenoids Plants Disease Research Fields Tabernaemontana elegans Stapf
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MS6105 is a PROTAC degrader targeting LDHA and LDHB, with DC50 values of 38 nM and 74 nM for degrading LDHA and LDHB in PANC-1 cells, respectively, and no hook effect is observed at high concentrations. MS6105 inhibits the proliferation of pancreatic cancer cells, and no obvious toxicity is observed after intraperitoneal administration in mice. MS6105 can be used for pancreatic cancer-related research .
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Cat. No.: HY-N7013
CAS No.: 252193-26-3
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Cat. No.: HY-N0476
CAS No.: 84104-71-2
Synonyms: Regelide; Abruslactone A
Category:
Triterpenes Terpenoids Celastraceae Plants Tripterygium wilfordii Hook. f. Disease Research Fields Inflammation/Immunology
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Cat. No.: HY-161108
CAS No.: 2597167-34-3
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PROTAC Chk1 degrader-1 is a Chk1-targeting PROTAC.PROTAC Chk1 degrader-1 recruits the Cereblon E3 ligase to induce ubiquitination and proteasomal degradation of Chk1.PROTAC Chk1 degrader-1 exhibits Chk1 degradation activity in malignant melanoma cells without showing a hook effect.PROTAC Chk1 degrader-1 can be used for the research of malignant melanoma .
Cat. No.: HY-149616
CAS No.: 3032388-42-1
PPM-3 is a highly selective ERK5 PROTAC degrader that mediates the degradation of ERK5 protein by recruiting VHL. PPM-3 inhibits ERK5 kinase activity with an IC50 of 62.4 nM. PPM-3-mediated ERK5 degradation exhibits a hook effect. PPM-3 exerts no significant direct inhibitory effect on the proliferation and migration of cancer cells. PPM-3 can be used in studies related to macrophage polarization and tumor immunity .
Cat. No.: HY-N4164
CAS No.: 80554-58-1
Cat. No.: HY-N4307
CAS No.: 72361-67-2
Category:
Infection Alkaloids Phenols Polyphenols Plants Lauraceae Disease Research Fields Isoquinoline Alkaloids Lindera aggregata (Sims) Kosterm.
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Cat. No.: HY-N1072
CAS No.: 37239-47-7
Category:
Terpenoids Sesquiterpenes Celastraceae Plants Tripterygium wilfordii Hook. f. Disease Research Fields Inflammation/Immunology
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
