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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
788 Results for "
factor-1
" in MedChemExpress (MCE) Product Catalog:
Products (788)
788 Results for "factor-1" in MCE Product Catalog:
183
183 Publications Verification
Art. -Nr.: HY-16749A
CAS. Nr.: 2040295-03-0
Synonyms: PLX-3397 hydrochloride
Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib hydrochloride exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib hydrochloride induces cell apoptosis and has anti-cancer activity [1].
183
Pexidartinib (PLX-3397) is a potent, orally active, selective, and ATP-competitive colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit inhibitor, with IC50s of 20 and 10 nM, respectively. Pexidartinib (PLX-3397) exhibits 10- to 100-fold selectivity for c-Kit and CSF1R over other related kinases. Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity. Pexidartinib has limited permeability to the blood-brain barrier, primarily through ABCB1 [1] .
159
159 Cited Publications
Art. -Nr.: HY-P7085
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage Colony Stimulating factor 1; Colony Stimulating factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage Colony-Stimulating factor; PG-M-CSF; Macrophage Colony-Stimulating factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colony Stimulating factor 1 (Macrophage)
Species:
Mouse
Source:
E. coli
76
76 Cited Publications
Synonyms: Campathecin; (S)-(+)-Camptothecin; CPT
71
71 Cited Publications
Art. -Nr.: HY-P70445
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL4; B_cell Stimulatory factor 1; Interleukin 4; B-Cell Stimulatory factor 1; IL-4; B Cell Growth factor 1; Lymphocyte Stimulatory factor 1; Binetrakin; Interleukin-4; Pitrakinra; BCGF-1; MGC79402; BCGF1; BSF-1; BSF1
Species:
Human
Source:
E. coli
66
66 Cited Publications
Art. -Nr.: HY-P7080
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL4; B_cell Stimulatory factor 1; Interleukin 4; B-Cell Stimulatory factor 1; IL-4; B Cell Growth factor 1; Lymphocyte Stimulatory factor 1; Binetrakin; Interleukin-4; Pitrakinra; BCGF-1; MGC79402; BCGF1; BSF-1; BSF1
Species:
Mouse
Source:
CHO
37
37 Cited Publications
Forschungsgebiete:
BAY 87-2243 is a highly potent and selective hypoxia-inducible factor-1 (HIF-1) inhibitor.
34
32
32 Cited Publications
Synonyms: AXL1717; Picropodophyllotoxin; PPP
28
28 Cited Publications
Art. -Nr.: HY-P70644
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL4; B_cell Stimulatory factor 1; Interleukin 4; B-Cell Stimulatory factor 1; IL-4; B Cell Growth factor 1; Lymphocyte Stimulatory factor 1; Binetrakin; Interleukin-4; Pitrakinra; BCGF-1; MGC79402; BCGF1; BSF-1; BSF1
Species:
Mouse
Source:
E. coli
27
27 Cited Publications
Art. -Nr.: HY-P7018
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1; Somatomedin-C; Insulin Like Growth factor 1; IGF1A; IGF-I; MGF; Insulin-Like Growth factor 1; Insulin-Like Growth factor IB; Insulin-Like Growth factor I; Insulin-Like Growth factor-I; IGFI; Alternative Protein IGF1; IGF; Somatomedin C; Insulin-Like
Species:
Human
Source:
E. coli
26
26 Cited Publications
Art. -Nr.: HY-18777
CAS. Nr.: 927822-86-4
Target:
Forschungsgebiete:
KC7F2 is a potent hypoxia inducible factor-1 (HIF-1) pathway inhibitor with an IC50 of 20 μM in LN229-HRE-AP cells, and with potential as a cancer therapy agent [1].
23
23 Cited Publications
Art. -Nr.: HY-P7050
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage Colony Stimulating factor 1; Colony Stimulating factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage Colony-Stimulating factor; PG-M-CSF; Macrophage Colony-Stimulating factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:
Human
Source:
E. coli
22
22
15
15 Cited Publications
Art. -Nr.: HY-P70653
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL4; B_cell Stimulatory factor 1; Interleukin 4; B-Cell Stimulatory factor 1; IL-4; B Cell Growth factor 1; Lymphocyte Stimulatory factor 1; Binetrakin; Interleukin-4; Pitrakinra; BCGF-1; MGC79402; BCGF1; BSF-1; BSF1
Species:
Mouse
Source:
HEK293
15
Target:
Forschungsgebiete:
NVP-AEW541 (AEW541 ) is an orally active inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with an IC50 value of 0.15 μM. NVP-AEW541 also inhibits InsR, IC50 with a value of 0.14 μM. NVP-AEW541 has antitumor activity [1].
13
13 Cited Publications
Target:
Forschungsgebiete:
GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 μM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling [1].
13
13 Cited Publications
Art. -Nr.: HY-117661
CAS. Nr.: 1818389-84-2
Forschungsgebiete:
SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease [1] .
12
12 Cited Publications
Art. -Nr.: HY-P7247
Reinheit: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CSF1; Macrophage Colony Stimulating factor 1; Colony Stimulating factor 1; Lanimostim; MCSF; MGC31930; Proteoglycan Macrophage Colony-Stimulating factor; PG-M-CSF; Macrophage Colony-Stimulating factor 1; CSF-1; M-CSF; CSF1-HERV-LTR71B Fusion Protein; Colo
Species:
Rat
Source:
CHO
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
