2. Cell Cycle/DNA Damage
  3. CDK
  4. Tacaciclib

Tacaciclib is a CDK inhibitor, antineoplastic effect.

For research use only. We do not sell to patients.

Tacaciclib

Tacaciclib Chemical Structure

CAS No. : 2768774-66-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
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Tacaciclib Related Antibodies

Top Publications Citing Use of Products

View All CDK Isoform Specific Products:

View All Isoforms
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85 CDK10 CDK15 CDK17 CDK18 CDK20 PITSLRE

  • Biological Activity

  • Purity & Documentation

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  • Customer Review

Description

Tacaciclib is a CDK inhibitor, antineoplastic effect[1].

Molecular Weight

528.65

Formula

C30H36N6O3
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(NC1=NNC(C2CC2)=C1)[C@H](C3=CC(C4=CN=C(NC(/C=C/CN5CCOCC5)=O)C=C4)=CC=C3)C(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (189.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8916 mL 9.4581 mL 18.9161 mL
5 mM 0.3783 mL 1.8916 mL 3.7832 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8916 mL 9.4581 mL 18.9161 mL 47.2903 mL
5 mM 0.3783 mL 1.8916 mL 3.7832 mL 9.4581 mL
10 mM 0.1892 mL 0.9458 mL 1.8916 mL 4.7290 mL
15 mM 0.1261 mL 0.6305 mL 1.2611 mL 3.1527 mL
20 mM 0.0946 mL 0.4729 mL 0.9458 mL 2.3645 mL
25 mM 0.0757 mL 0.3783 mL 0.7566 mL 1.8916 mL
30 mM 0.0631 mL 0.3153 mL 0.6305 mL 1.5763 mL
40 mM 0.0473 mL 0.2365 mL 0.4729 mL 1.1823 mL
50 mM 0.0378 mL 0.1892 mL 0.3783 mL 0.9458 mL
60 mM 0.0315 mL 0.1576 mL 0.3153 mL 0.7882 mL
80 mM 0.0236 mL 0.1182 mL 0.2365 mL 0.5911 mL
100 mM 0.0189 mL 0.0946 mL 0.1892 mL 0.4729 mL
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Tacaciclib Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tacaciclib2768774-66-7CDKCyclin dependent kinaseInhibitorinhibitorinhibit

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