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TNF-α-IN-11

TNF-α-IN-11 (Compound 10) is a TNF-α inhibitor with a KD value of 12.06 μM. TNF-α-IN-11 binds to TNF-α and blocks the activation of TNF-α-trigged caspase and NF-κB signaling pathway. TNF-α-IN-11 inhibits the phosphorylation of IκBα, as well as the nuclear translocation of NF κB p65. TNF-α-IN-11 can be used for research of TNF-α-mediated autoimmune diseases.

For research use only. We do not sell to patients.

  • CAS No.: 2945197-77-1
  • Formula: C24H26N2O5
  • Molecular Weight:422.47
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • TNF-α-IN-11 Chemical Structure
    TNF-α-IN-11 Chemical Structure
CAS No.: 2945197-77-1
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Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All TNF Receptor Isoforms

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All NF-κB Isoforms

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All Caspase Isoforms

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100 mg

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  • TNF-α-IN-11 Chemical Structure
    TNF-α-IN-11 Chemical Structure
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  • TNF-α-IN-11