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Vacquinol-1 (Synonyms: NSC13316)

Cat. No.: HY-19345
Handling Instructions

Vacquinol-1 (NSC13316) is a MKK4-specific activator that activates MAPK pathways. Vacquinol-1 specifically induces human glioblastoma cell (GC) death, attenuates tumor progression and prolongs survival in a glioblastoma multiforme (GBM) mouse model. Vacquinol-1 also induces apoptosis in hepatocellular carcinoma (HCC)cell.

For research use only. We do not sell to patients.

Vacquinol-1 Chemical Structure

Vacquinol-1 Chemical Structure

CAS No. : 5428-80-8

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Description

Vacquinol-1 (NSC13316) is a MKK4-specific activator that activates MAPK pathways[1]. Vacquinol-1 specifically induces human glioblastoma cell (GC) death, attenuates tumor progression and prolongs survival in a glioblastoma multiforme (GBM) mouse model[2]. Vacquinol-1 also induces apoptosis in hepatocellular carcinoma (HCC)cell[3].

Molecular Weight

352.86

Formula

C21H21ClN2O

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 30 mg/mL (85.02 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8340 mL 14.1699 mL 28.3399 mL
5 mM 0.5668 mL 2.8340 mL 5.6680 mL
10 mM 0.2834 mL 1.4170 mL 2.8340 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
Vacquinol-1
Cat. No.:
HY-19345
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