ADP-β-S trilithium

ADP-β-S (0.2-2 mM; 30 min) trilithium enhances IL-1β production in primary cultured murine microglia via the P2Y12 receptor, with significant effects observed at 0.2 mM and 2 mM concentrations when paired with LPS or LPS plus ATP stimulation^[1].
ADP-β-S (0.2 mM; 30 min) trilithium enhances LPS plus ATP-induced IL-1β production in wild-type MG6 murine microglial cells, but not in P2ry12 KO MG6 cells, confirming dependence on the P2Y12 receptor^[1].
ADP-β-S (0.2 mM; 24 h) trilithium enhances LPS-induced IL-6 production in MG6 murine microglial cells via the P2Y12 receptor^[1].
ADP-β-S (0.2 mM; 24 h) trilithium enhances LPS-induced IL-6 production in primary cultured murine microglia via the P2Y12 receptor^[1].
ADP-β-S (0.2 mM; 24 h) trilithium enhances LPS-induced IL-6 production in wild-type MG6 murine microglial cells, but not in P2ry12 KO MG6 cells, confirming dependence on the P2Y12 receptor^[1].
ADP-β-S (0.2 mM; 24 h) trilithium potentiates LPS-induced NF-κB activation, including nuclear translocation and phosphorylation, in MG6 murine microglial cells^[1].
ADP-β-S (trilithium) (0.2-2 mM; 30 min) activates caspase-1 at 2 mM and enhances LPS plus ATP-induced caspase-1 activation at 0.2 mM in MG6 murine microglial cells^[1].
ADP-β-S (0.2 mM; 30 min) trilithium enhances LPS plus ATP-induced mitochondrial membrane potential disruption in MG6 murine microglial cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.