2. PI3K/Akt/mTOR Immunology/Inflammation MAPK/ERK Pathway NF-κB
  3. AP-1 Akt NF-κB p38 MAPK PI3K
  4. Antcin K

Antcin K is a selective inhibitor targeting the PI3K/Akt, NF-κB, MEK1/2-ERK, p38 and AP-1 pathways. Antcin K upregulates IL-10 expression, thereby inhibiting the production of pro-inflammatory factors, blocking monocyte adhesion, reducing tissue damage, and promoting myogenesis. Antcin K has significant anti-inflammatory, anti-damage and tissue protective activities. Antcin K is mainly used in the research of inflammation-related diseases such as periodontitis, rheumatoid arthritis, and skeletal muscle injury.

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Antcin K

Antcin K Chemical Structure

CAS No. : 741268-13-3

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Based on 1 publication(s) in Google Scholar

Antcin K Related Antibodies

Top Publications Citing Use of Products

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c-Fos FosB Fra1/FOSL1 Fra2/FOSL2 c-Jun

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Akt Akt1 Akt2 Akt3

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

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p38 MAPK Akt1 p38α p38β MAPK13 p38δ p38γ

View All PI3K Isoform Specific Products:

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PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

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Description

Antcin K is a selective inhibitor targeting the PI3K/Akt, NF-κB, MEK1/2-ERK, p38 and AP-1 pathways. Antcin K upregulates IL-10 expression, thereby inhibiting the production of pro-inflammatory factors, blocking monocyte adhesion, reducing tissue damage, and promoting myogenesis. Antcin K has significant anti-inflammatory, anti-damage and tissue protective activities. Antcin K is mainly used in the research of inflammation-related diseases such as periodontitis, rheumatoid arthritis, and skeletal muscle injury[1][2][3].

Molecular Weight

488.66

Formula

C29H44O6
CAS No.
SMILES

C[C@@]12C3=C([C@H](C[C@@]1([H])[C@@](O)([C@@H](CC2)O)C)O)[C@@]4([H])[C@](CC3=O)([C@@](CC4)([H])[C@H](C)CCC(C(C)C(O)=O)=C)C
Structure Classification
Initial Source

Antrodia cinnamomea
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antcin K Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antcin K741268-13-3AP-1AktNF-κBp38 MAPKPI3KActivator Protein 1PKBProtein kinase BNuclear factor-κBNuclear factor-kappaBPhosphoinositide 3-kinaseInhibitorinhibitorinhibit

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