A-1592668
A-1592668 is a selective CDK9 inhibitor. A-1592668 induces Apoptosis. A-1592668 plus Venetoclax (HY-15531) co-treatment inhibits the growth of Jeko-1 tumors.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1628314-13-5
- Formel: C26H27F2N3O3
- Molecular Weight:467.51
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
CDK9 |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MV4-11 | IC50 |
138 nM
Compound: 63; A-1592668
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 24 hrs by Cell-Titer Glo assay
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 24 hrs by Cell-Titer Glo assay
|
[PMID: 32866383] |
Chemical Information
-
CAS. Nr. 1628314-13-5
-
Molecular Weight 467.51
-
Formel C26H27F2N3O3
-
SMILES
FC1=CN=C(NC(C2=CCN([C@@H]3CC[C@H](CC3)C(O)=O)CC2)=C4)C4=C1C5=C(C=CC(F)=C5)OC
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Powered by Bioz