1. GPCR/G Protein Neuronal Signaling
  2. mGluR
  3. AZD 2066 sulfate

AZD 2066 sulfate is a mGluR5 antagonist and also the sulfate salt of 4-(5-{(1R)-1-ethoxy}-4-methyl-4H-1,2,4-triazol-3-yl) pyridine. AZD 2066 sulfate is used in research on various diseases including Alzheimer's disease, autism, and obesity.

For research use only. We do not sell to patients.

AZD 2066 sulfate

AZD 2066 sulfate Chemical Structure

CAS No. : 934282-57-2

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Description

AZD 2066 sulfate is a mGluR5 antagonist and also the sulfate salt of 4-(5-{(1R)-1-ethoxy}-4-methyl-4H-1,2,4-triazol-3-yl) pyridine. AZD 2066 sulfate is used in research on various diseases including Alzheimer's disease, autism, and obesity[1].

IC50 & Target[1]

mGlu5

 

In Vitro

AZD 2066 sulfate is used in the research of gastroesophageal reflux disease, Alzheimer's disease, senile dementia, AIDS-induced dementia, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, migraine, epilepsy, schizophrenia, depression, anxiety disorder, acute anxiety disorder, obsessive-compulsive disorder, retinopathy, diabetic retinopathy, glaucoma, tinnitus, chemotherapy-induced neuropathy, postherpetic neuralgia, trigeminal neuralgia, tolerance, dependence, addiction, craving disorder, fragile X syndrome, autism, mental retardation, Down syndrome, inflammatory pain, neuropathic pain, arthritis, rheumatism, low back pain, postoperative pain, angina pectoris, renal colic, biliary colic, dysmenorrhea, gout, stroke, head trauma, hypoxic injury, ischemic injury, hypoglycemia, cardiovascular disease, irritable bowel syndrome, functional dyspepsia, cough, and obesity[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

479.89

Formula

C19H18ClN5O6S

CAS No.
SMILES

O=S(O)(O)=O.CN1C(C2=CC=NC=C2)=NN=C1O[C@@H](C3=NOC(C4=CC(Cl)=CC=C4)=C3)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
AZD 2066 sulfate
Cat. No.:
HY-110255C
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