CA/HDAC-IN-1
CA/HDAC-IN-1 (Compound 11) is a CA and HDAC inhibitor with Ki values of 7.4 nM, 31.0 nM, and 7.3 nM for hCA II, hCA IX, and hCA XII, respectively, and IC50 values of 0.21 μM and 3.60 μM for HDAC3 and HDAC8, respectively. CA/HDAC-IN-1 has anti-cancer activity against colon cancer, breast cancer, and melanoma.
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- Formule: C21H21N5O4S
- Masse moléculaire:439.49
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
hCA II 7.4 nM (Ki) |
hCA XII 7.3 nM (Ki) |
HDAC3 0.21 μM (IC50) |
HDAC8 3.60 μM (IC50) |
hCA IX 31.0 nM (Ki) |
Chemical Information
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Masse moléculaire 439.49
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Formule C21H21N5O4S
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SMILES
O=C(NC1=CC=CC=C1N)C2=CC=C(CNC(NC3=CC=C(S(=O)(N)=O)C=C3)=O)C=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CA/HDAC-IN-1 Related Classifications
HY-179271 Related Classifications
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