SLM6
SLM6 is a sangivamycin-like molecule. SLM6 is a CDK9 inhibitor. SLM6 inhibits CDK9/cyclin K and CDK9/cyclin T1 kinase activity with IC50s of 280 nM and 133 nM, respectively. SLM6 also inhibits CDK1/cyclin B and CDK2/ cyclin A with IC50s of less than 300 nM. SLM6 induces apoptosis in multiple myeloma (MM) cells.
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- CAS No.: 22242-91-7
- Formule: C12H17N7O4
- Masse moléculaire:323.31
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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CDK9/cyclinT1 133 nM (IC50) |
Chemical Information
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CAS No. 22242-91-7
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Masse moléculaire 323.31
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Formule C12H17N7O4
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SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=C(C(NN)=N)C3=C(N)N=CN=C32)O1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SLM6 Related Classifications
HY-136841 Related Classifications
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