1. Cell Cycle/DNA Damage
  2. CDK
  3. Cdc7-IN-1

Cdc7-IN-1 

Cat. No.: HY-101523
Handling Instructions

Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death.

For research use only. We do not sell to patients.

Cdc7-IN-1 Chemical Structure

Cdc7-IN-1 Chemical Structure

CAS No. : 1402055-25-7

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Description

Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1].

IC50 & Target

IC50: 0.6 nM (Cdc7, at 1 mM ATP)[1]

Molecular Weight

409.82

Formula

C₂₁H₁₆ClN₃O₄

CAS No.

1402055-25-7

SMILES

O=C1C(C(OCC)=O)=C(NC2=C(Cl)C=CC=C2)O/C1=C\C3=CNC4=C3C=CC=N4

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Cdc7-IN-1
Cat. No.:
HY-101523
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