Cdc7-IN-12
Cdc7-IN-12 (compound 1) is a potent CDC7 inhibitor with an IC50 of <1 nM. Cdc7-IN-12 shows antiproliferative activities with IC50 of 100-1000 nM in COLO205 cells. Cdc7-IN-12 has the potential for the research of cancer.
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- CAS No.: 2764865-33-8
- Formule: C16H14N2O2S
- Masse moléculaire:298.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
[1]|
Cdc7 <1 nM (IC50) |
Chemical Information
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CAS No. 2764865-33-8
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Masse moléculaire 298.36
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Formule C16H14N2O2S
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SMILES
CC1=C2CCCOC3=C(SC(C(N1)=O)=C23)C4=CC=NC=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Cdc7-IN-12 Related Classifications
HY-143385 Related Classifications
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