Cimigenoside
Based on 1 Customer Validation
Cimigenoside is an active compound from genus Cimicifuga.
For research use only. We do not sell to patients.
- Purity: 98.90%
- CAS No.: 27994-11-2
- Formula: C35H56O9
- Molecular Weight:620.81
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 27994-11-2
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Appearance Solid
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Molecular Weight 620.81
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Formula C35H56O9
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Color White to off-white
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SMILES
C[C@]([C@](CC1)([C@]([C@@H](C2)C)([H])C34O[C@H](C(C)(O)C)[C@]2([H])O4)C)([C@H]3O)[C@@](CC[C@@]5([H])C6(C)C)([H])[C@@]71[C@]5(CC[C@@H]6O[C@@](OC[C@@H](O)[C@@H]8O)([H])[C@@H]8O)C7
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (161.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (4.03 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6108 mL | 8.0540 mL | 16.1080 mL | 40.2700 mL |
| 5 mM | 0.3222 mL | 1.6108 mL | 3.2216 mL | 8.0540 mL | |
| 10 mM | 0.1611 mL | 0.8054 mL | 1.6108 mL | 4.0270 mL | |
| 15 mM | 0.1074 mL | 0.5369 mL | 1.0739 mL | 2.6847 mL | |
| 20 mM | 0.0805 mL | 0.4027 mL | 0.8054 mL | 2.0135 mL | |
| 25 mM | 0.0644 mL | 0.3222 mL | 0.6443 mL | 1.6108 mL | |
| 30 mM | 0.0537 mL | 0.2685 mL | 0.5369 mL | 1.3423 mL | |
| 40 mM | 0.0403 mL | 0.2013 mL | 0.4027 mL | 1.0067 mL | |
| 50 mM | 0.0322 mL | 0.1611 mL | 0.3222 mL | 0.8054 mL | |
| 60 mM | 0.0268 mL | 0.1342 mL | 0.2685 mL | 0.6712 mL | |
| 80 mM | 0.0201 mL | 0.1007 mL | 0.2013 mL | 0.5034 mL | |
| 100 mM | 0.0161 mL | 0.0805 mL | 0.1611 mL | 0.4027 mL |
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