country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-129694

Copy Link Print Information

Lenoremycin

(Synonyms: Ro 21-6150; Antibiotic A-130-A)

Lenoremycin (Ro 21-6150) is a microbial metabolite. Lenoremycin decreases β-catenin and cyclin D1 proteins levels. Lenoremycin decreases cancer stem cells (CSCs) populations via inducing reactive oxygen species production.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 51257-84-2
Fòrmula: C₄₇H₇₈O₁₃
Peso molecular:851.11

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Lenoremycin Chemical Structure

No. CAS: 51257-84-2

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

Ver todos los productos específicos de isoformas CDK :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	1.2 μM Compound: 9	Cytotoxicity against human A549 cells assessed as decrease in cell viability after 48 hrs by resazurin assay Cytotoxicity against human A549 cells assessed as decrease in cell viability after 48 hrs by resazurin assay	[PMID: 28029795]
HEK293	EC₅₀	38 nM Compound: 9	Modulation of unfolded protein response in tunicamycin-treated HEK293 cells after 48 hrs by ASGR-Cluc secretion assay Modulation of unfolded protein response in tunicamycin-treated HEK293 cells after 48 hrs by ASGR-Cluc secretion assay	[PMID: 28029795]

Chemical Information

No. CAS 51257-84-2
Peso molecular 851.11
Fòrmula C₄₇H₇₈O₁₃
SMILES

C[C@H]1[C@]2(O[C@](C[C@H]1O[C@@H]3O[C@@H]([C@H](CC3)OC)C)([H])[C@@H](C)/C=C(C)/C([C@H](C)C[C@H](C)C(O)=O)=O)O[C@@](CC2)([C@]4([H])O[C@@]5([C@@H](CC4)C)O[C@]([C@@]6([H])O[C@](O)([C@@H](C[C@@H]6C)C)CO)([H])C[C@@H]5C)C
Synonyms

Ro 21-6150; Antibiotic A-130-A
Structure Classification
- Antibiotics
- Other Antibiotics
Initial Source
- Microorganisms
Streptomyces hygroscopicus
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ikeda H, et al. Identification of the polyether ionophore lenoremycin through a new screening strategy for targeting cancer stem cells. J Antibiot (Tokyo). 2022 Dec;75(12):671-678. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto

Amount: USD 0.00

Actividad biológica
- Descripciòn
Chemical Information
Pureza y Documentación
Referencias

Nombre del producto:
Referencia número:
Cantidad:
MCE Japan Authorized Agent:

Nombre del producto:
No. CAS:
Species:
Pureza:
Cantidad:

Lenoremycin

Ver todos los productos específicos de isoformas CDK

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Lenoremycin Related Classifications

HY-129694 Related Classifications