Brd9 - bromodomain containing 9 Gene
Species: Mus musculus
Gene Type: protein coding
Gene ID: 105246
About Brd9
Chromosome 13: 74,085,930-74,109,014 forward strand.GRCm39:CM001006.3
This gene has 12 transcripts (splice variants), 203 orthologues, 2 paralogues and is associated with 20 phenotypes. Ubiquitous expression in CNS E14 (RPKM 2.2), CNS E18 (RPKM 19.3) and 28 other tissues.
Summary
Predicted to enable lysine-acetylated histone binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Part of SWI/SNF complex. Is expressed in female reproductive system and urinary system. Orthologous to human BRD9 (bromodomain containing 9). [provided by Alliance of Genome Resources, Apr 2022]
Brd9 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001378948.1 | NP_001365877.1 | bromodomain-containing protein 9 isoform 4 |
| NM_001308041.2 | NP_001294970.1 | bromodomain-containing protein 9 isoform 2 |
| NM_001378947.1 | NP_001365876.1 | bromodomain-containing protein 9 isoform 3 |
| NM_001024508.4 | NP_001019679.2 | bromodomain-containing protein 9 isoform 1 |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| part of SWI/SNF complex |
IDA
IDA: Inferred from direct assay
|
23644491 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
Brd9 Protein Structure
Bromo_brd7_like
Bromo_brd7_like: cd05513 (139 - 236)
DUF3512
DUF3512: pfam12024 (285 - 464)
- 0
- 100
- 200
- 300
- 400
- 500
- 597 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
bromodomain-containing protein 9 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(54)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-153367 | FHD-609 | Degrader | 98.95% | Unkown |
| HY-100351 | BI-7273 | Inhibitor | 99.75% | Unkown |
| HY-145925B | CFT8634 | Inhibitor | 98.10% | Unkown |
| HY-114322 | VZ185 | Inhibitor | 99.95% | Unkown |
| HY-100352 | BI-9564 | Inhibitor | 98.96% | Unkown |
| HY-117690 | dBRD9 | Degrader | 99.75% | Unkown |
| HY-110374 | NVS-CECR2-1 | Inhibitor | 99.40% | Unkown |
| HY-100517 | TP-472 | Inhibitor | 99.54% | Unkown |
| HY-149420 | BRD7-IN-2 | Inhibitor | 99.29% | Unkown |
| HY-156744 | DBr-1 | Degrader | 98.87% | Unkown |
| HY-148739 | dBRD 9-A | Degrader | 99.50% | Unkown |
| HY-103632 | PROTAC BRD9 Degrader-1 | Inhibitor | 99.16% | Unkown |
| HY-107477 | GSK8573 | 99.53% | Unkown | |
| HY-159579 | CW-3308 | 99.43% | Unkown | |
| HY-123621 | GNE-375 | Inhibitor | 99.93% | Unkown |
| HY-145403 | PROTAC BRD9 Degrader-4 | Degrader | 99.02% | Unkown |
| HY-155361 | PROTAC BRD9 Degrader-7 | Degrader | 99.29% | Unkown |
| HY-49393 | BRD9 ligand-6 | 97.51% | Unkown | |
| HY-101121 | NI-42 | Inhibitor | 99.53% | Unkown |
| HY-114205A | TP-238 hydrochloride | Inhibitor | ≥99.0% | Unkown |
| HY-116227 | (2S,3R)-LP99 | Inhibitor | 99.4% | Unkown |
| HY-117690A | dBRD9 dihydrochloride | Degrader | 99.91% | Unkown |
| HY-145947 | PROTAC BRD9 Degrader-5 | Degrader | / | Unkown |
| HY-111905A | BRD7-IN-1 free base | Inhibitor | / | Unkown |
| HY-182082 | XYD270 | / | Unkown | |
| HY-182766 | AMX-883 | Degrader | / | Unkown |
| HY-143270 | PROTAC BRD9-binding moiety 5 | / | Unkown | |
| HY-145925C | (S,R)-CFT8634 | Inhibitor | / | Unkown |
| HY-181951 | PROTAC BRD9 Degrader-11 | Degrader | / | Unkown |
| HY-153632 | PROTAC BRD9 Degrader-6 | Degrader | 98.19% | Unkown |
| HY-156401 | BRD9 Degrader-1 | Degrader | / | Unkown |
| HY-181949 | PROTAC BRD9 Degrader-10 | / | Unkown | |
| HY-184210 | XYD224 | Degrader | / | Unkown |
| HY-150797 | QA-68 | Inhibitor | / | Unkown |
| HY-114205 | TP-238 | Inhibitor | / | Unkown |
| HY-170314 | EA-89 | Degrader | / | Unkown |
| HY-163809 | BRD9 Degrader-2 | Degrader | / | Unkown |
| HY-159596 | Naphthyridin-Me-dimethoxybenzene-COOH | / | Unkown | |
| HY-181952 | BRD9 ligand-11 | Ligand | / | Unkown |
| HY-169988 | BRD9 ligand-5 | Inhibitor | / | Unkown |
| HY-178345 | ZZ7-23-022 | Degrader | / | Unkown |
| HY-168695 | BRD9 ligand-7 | Ligand | / | Unkown |
| HY-162651 | PROTAC BRD9 Degrader-8 | Degrader | / | Unkown |
| HY-150872 | BRD9 ligand-3 | Ligand | / | Unkown |
| HY-163811 | BRD9 Degrader-4 | Inhibitor | / | Unkown |
| HY-163810 | BRD9 Degrader-3 | Degrader | / | Unkown |
| HY-184211 | BRD9 ligand-14 | Ligand | / | Unkown |
| HY-177729 | PROTAC BRD9 Degrader-9 | Degrader | / | Unkown |
| HY-149806 | Bromodomain IN-2 | Inhibitor | / | Unkown |
| HY-123616 | BI 7271 | Degrader | / | Unkown |
| HY-182084 | BRD9 ligand-12 | Ligand | / | Unkown |
| HY-175915 | BRD9 ligand-13 | / | Unkown | |
| HY-181950 | BRD9 ligand-10 | Ligand | / | Unkown |
| HY-107446 | BI-7273 acid | Degrader | / | Unkown |
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