Hdac11 - histone deacetylase 11 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 297453

About Hdac11

Primary_assembly 4: 123,650,157-123,667,405 forward strand.mRatBN7.2:CM026977.1

This gene has 2 transcripts (splice variants), 198 orthologues and 12 paralogues. Biased expression in Brain (RPKM 355.), Kidney (RPKM 92.9) and 5 other tissues.

Summary

Predicted to enable histone deacetylase activity. Involved in oligodendrocyte development. Located in nucleus. Orthologous to human HDAC11 (histone deacetylase 11). [provided by Alliance of Genome Resources, Apr 2022]

Hdac11 Products (1)

mRNA Protein Name
NM_001106610.2 NP_001100080.2 histone deacetylase 11

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in oligodendrocyte development IMP
IMP: Inferred from mutant phenotype
18627006 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Hdac11 Protein Structure

HDAC_classIV

HDAC_classIV: cd09993 (34 - 318)

  • 0
  • 100
  • 200
  • 300
  • 347 a.a.
Protein Preferred Names Protein Names

histone deacetylase 11

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10221 Vorinostat Inhibitor 99.96% Yes
HY-109015 Tucidinostat Inhibitor 98.74% Unkown
HY-12164 Mocetinostat Inhibitor 99.68% Yes
HY-14842 Givinostat Inhibitor 98.67% Yes
HY-13322 Pracinostat Inhibitor 99.80% Yes
HY-14842B Givinostat hydrochloride monohydrate Inhibitor 99.63% Yes
HY-14842A Givinostat hydrochloride Inhibitor 98.06% Yes

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-150109 Purinostat mesylate Inhibitor 99.45% Phase 3
HY-15433 Quisinostat Inhibitor 99.71% Phase 2
HY-13522 Fimepinostat Inhibitor 99.95% Phase 2
HY-16012 Domatinostat tosylate Inhibitor 99.66% Phase 2

Pre-clinical Phase

Bioactive Molecules (59)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13428 Tubacin Inhibitor 98.71% Unkown
HY-18998 LMK-235 Inhibitor 99.61% Unkown
HY-112285 FT895 Inhibitor 99.84% Unkown
HY-128918 SIS17 Inhibitor 99.43% Unkown
HY-16699 Nexturastat A Inhibitor 98.69% Unkown
HY-145757 Elevenostat Inhibitor 95.07% Unkown
HY-15433A Quisinostat dihydrochloride Inhibitor 99.05% Unkown
HY-16012A Domatinostat Inhibitor 99.34% Unkown
HY-115475 SW-100 Inhibitor 99.93% Unkown
HY-126330 SS-208 Inhibitor 99.00% Unkown
HY-135714 Bavarostat Inhibitor 99.51% Unkown
HY-172157 HDAC11-IN-2 Inhibitor 99.52% Unkown
HY-176542 TD034 Inhibitor 99.77% Unkown
HY-143412 MIR002 Inhibitor 99.0% Unkown
HY-114483 AES-135 Inhibitor 98.68% Unkown
HY-143411 GEM144 Inhibitor / Unkown
HY-173444 HDAC11-IN-3 Inhibitor 99.70% Unkown
HY-110280 MC1742 Inhibitor 98.95% Unkown
HY-182019 HDAC11-IN-5 Inhibitor 98.25% Unkown
HY-138831 AES-350 Inhibitor 99.30% Unkown
HY-157740 XSJ-10 Inhibitor 95.16% Unkown
HY-178970 HDAC11-IN-4 Inhibitor 95.0% Unkown
HY-146684 HDAC-IN-36 Inhibitor / Unkown
HY-176868 Rodin-C Inhibitor / Unkown
HY-173076 HDAC11-IN-1 Inhibitor / Unkown
HY-161778 ZG-126 Inhibitor / Unkown
HY-157481 HDAC1-IN-6 Inhibitor / Unkown
HY-179019 HDAC-IN-94 Inhibitor / Unkown
HY-15144B (S)-Trichostatin A Inhibitor / Unkown
HY-151263 G4/HDAC-IN-1 Inhibitor / Unkown
HY-152226 MC2590 Inhibitor 98.71% Unkown
HY-152225 MC2625 Inhibitor / Unkown
HY-180811 ALK/HDAC-IN-2 Inhibitor / Unkown
HY-143877 NN-390 Inhibitor / Unkown
HY-159171 sEH/HDAC6-IN-2 Inhibitor / Unkown
HY-184203 SM-06-09 Inhibitor / Unkown
HY-181579 HDAC6-IN-74 Inhibitor / Unkown
HY-157889 ZINC000028464438 Inhibitor / Unkown
HY-181009 HDAC-IN-98 Inhibitor 98.36% Unkown
HY-163207 sEH/HDAC6-IN-1 Inhibitor / Unkown
HY-152173 HDAC-IN-51 Inhibitor / Unkown
HY-170379 HDAC-IN-84 Inhibitor / Unkown
HY-149283 JAK/HDAC-IN-2 Inhibitor / Unkown
HY-183560 HDAC6-IN-82 Inhibitor / Unkown
HY-182717 FT234 Inhibitor / Unkown
HY-161350 ALK/HDAC-IN-1 Inhibitor / Unkown
HY-162630 HDAC6-IN-44 Inhibitor / Unkown
HY-150772 Tubulin/HDAC-IN-1 Inhibitor / Unkown
HY-180214 HDAC6-IN-69 Inhibitor / Unkown
HY-147966 HDAC-IN-43 Inhibitor / Unkown
HY-184574 HDAC-IN-104 Inhibitor / Unkown
HY-162658 Leuxinostat Inhibitor / Unkown
HY-150595 HDAC6-IN-10 Inhibitor / Unkown
HY-174302 PIM-1/HDAC-IN-2 Inhibitor / Unkown
HY-179272 Wee1/HDAC-IN-1 Inhibitor / Unkown
HY-163803 CM-444 Inhibitor / Unkown
HY-169400 HDACs/EZH2-IN-1 Inhibitor / Unkown
HY-15433B Quisinostat hydrochloride Inhibitor / Unkown
HY-175030 TNI-97 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hdac11 NCBI NCBI:79885