CSF1R - colony stimulating factor 1 receptor Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 489188

About CSF1R

Primary_assembly 4: 59,444,535-59,544,925 forward strand.ROS_Cfam_1.0:CM025103.1

This gene has 3 transcripts (splice variants), 273 orthologues and 54 paralogues.

CSF1R Products (1)

mRNA Protein Name
XM_038663657.1 XP_038519585.1 macrophage colony-stimulating factor 1 receptor

CSF1R Protein Structure

Ig_3

Ig_3: pfam13927 (20 - 84)

Ig

Ig: cd00096 (37 - 41)

Ig

Ig: cd00096 (54 - 57)

Ig

Ig: cd00096 (65 - 70)

Ig

Ig: cd00096 (80 - 85)

Ig

Ig: cd00096 (93 - 96)

IG_like

IG_like: smart00410 (112 - 194)

Ig

Ig: cl11960 (202 - 294)

Ig

Ig: cd00096 (219 - 223)

Ig

Ig: cd00096 (233 - 237)

Ig

Ig: cd00096 (258 - 262)

Ig

Ig: cd00096 (274 - 279)

Ig

Ig: cd00096 (287 - 290)

Ig

Ig: cl11960 (298 - 397)

Ig

Ig: cd00096 (318 - 322)

Ig

Ig: cd00096 (332 - 336)

Ig

Ig: cd00096 (361 - 365)

Ig

Ig: cd00096 (375 - 380)

Ig

Ig: cd00096 (388 - 391)

Ig_3

Ig_3: pfam13927 (398 - 485)

Ig

Ig: cd00096 (425 - 429)

Ig

Ig: cd00096 (460 - 464)

Ig

Ig: cd00096 (478 - 483)

PKc_like

PKc_like: cl21453 (539 - 911)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 967 a.a.
Protein Preferred Names Protein Names

macrophage colony-stimulating factor 1 receptor

  • colony stimulating factor 1 receptor, formerly McDonough feline sarcoma viral (v-fms) oncogene homolog

Recombinant CSF1R Proteins

Cat. No. Product Name Accession Purity
HY-P78637 CSF1R Protein, Canine (HEK293, His) E2RJV2 (V20-P510) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16749 Pexidartinib 99.64% Yes
HY-16749A Pexidartinib hydrochloride 99.82% Yes

Clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Phase
HY-132166 Velzatinib Inhibitor 99.40% Phase 3
HY-109190 Seralutinib Inhibitor 99.94% Phase 3
HY-145601 Tinengotinib Inhibitor 99.57% Phase 3
HY-124526 Chiauranib Inhibitor 98.97% Phase 3
HY-153920A Pimicotinib hydrochloride Inhibitor / Phase 3
HY-12768 Sotuletinib Inhibitor 99.97% Phase 2
HY-109086 Edicotinib Inhibitor 99.68% Phase 2
HY-19772 GSK3117391 Inhibitor 99.40% Phase 2
HY-159838 Enrupatinib Inhibitor 98.90% Phase 2
HY-161025 SYHA1813 Inhibitor 99.46% Phase 2
HY-136362 ARRY-382 Inhibitor 99.95% Phase 2
HY-159503A Segigratinib hydrochloride Inhibitor / Phase 2
HY-114153A PLX5622 hemifumarate Inhibitor 99.93% Phase 1
HY-100491 H3B-6527 Inhibitor 98.0% Phase 1
HY-111787 Elzovantinib Inhibitor 99.93% Phase 1
HY-101768 PRN1371 Inhibitor 99.78% Phase 1
HY-10204 OSI-930 98.33% Phase 1
Inhibitory Antibodies (6)
Cat. No. Product Name Effect
Purity Phase
HY-P99245 Emactuzumab Inhibitor 97.60% Phase 3
HY-P990043 Iluzanebart 98.63% Phase 2
HY-P99452 Axatilimab Inhibitor 99.59% Phase 2
HY-P99259 Cabiralizumab Inhibitor 99.73% Phase 2
HY-P99368 Lacnotuzumab Inhibitor 99.9% Phase 2
HY-P991048 AMG-820 Inhibitor 98% Phase 2

Pre-clinical Phase

Bioactive Molecules (65)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-114153 PLX5622 Inhibitor 99.95% Unkown
HY-114153C PLX5622 in AIN-76A Diet (1200 ppm) Inhibitor / Unkown
HY-50905 Dovitinib Inhibitor 99.88% Yes
HY-12768A Sotuletinib hydrochloride Inhibitor 99.43% Unkown
HY-153920 Pimicotinib Inhibitor 99.92% Unkown
HY-10408 Ki20227 Inhibitor 99.51% Unkown
HY-101774 CSF1R-IN-1 Inhibitor 98.04% Unkown
HY-159108 AZ683 Inhibitor 98.57% Unkown
HY-117244 AZD7507 Inhibitor 99.57% Unkown
HY-147615 CSF1R-IN-12 98.75% Unkown
HY-122906 JTE-952 Inhibitor 99.86% Unkown
HY-152830 Adrixetinib 99.55% Unkown
HY-126297 c-Fms-IN-10 Inhibitor 98.63% Unkown
HY-139990 CSF1R-IN-3 Inhibitor 98.10% Unkown
HY-112451 cFMS Receptor Inhibitor II Inhibitor 99.88% Unkown
HY-132935 BPR1R024 Inhibitor 98.50% Unkown
HY-160842 CSF1R-IN-24 Inhibitor 98.10% Unkown
HY-117273 AZ304 Inhibitor 99.77% Unkown
HY-119942 c-Fms-IN-8 Inhibitor 99.50% Unkown
HY-152830A Adrixetinib TFA 99.82% Unkown
HY-101526 GENZ-882706 Inhibitor / Unkown
HY-13075 c-Fms-IN-3 Inhibitor 98.83% Unkown
HY-132935A BPR1R024 mesylate Inhibitor / Unkown
HY-RS03228 CSF1R Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-13493 AC710 Inhibitor 99.57% Unkown
HY-13496 JNJ-28312141 Inhibitor / Unkown
HY-101034 CHMFL-ABL/KIT-155 / Unkown
HY-12768B Sotuletinib dihydrochloride Inhibitor / Unkown
HY-174366 JMC14 Inhibitor / Unkown
HY-109086A Edicotinib hydrochloride Inhibitor / Unkown
HY-13496A JNJ-28312141 hydrochloride Inhibitor / Unkown
HY-144040 CSF1R-IN-4 / Unkown
HY-144041 CSF1R-IN-5 Inhibitor / Unkown
HY-144042 CSF1R-IN-6 / Unkown
HY-147608 CSF1R-IN-7 Inhibitor / Unkown
HY-147609 CSF1R-IN-8 Inhibitor / Unkown
HY-147610 CSF1R-IN-9 Inhibitor / Unkown
HY-147611 CSF1R-IN-10 Inhibitor / Unkown
HY-147616 CSF1R-IN-13 / Unkown
HY-147617 CSF1R-IN-14 / Unkown
HY-153012 Axl/Mer/CSF1R-IN-1 Inhibitor / Unkown
HY-153243 IACS-9439 Inhibitor / Unkown
HY-153277 Axl/Mer/CSF1R-IN-2 Inhibitor / Unkown
HY-155001 CSF1R-IN-15 Inhibitor / Unkown
HY-155550 CSF1R-IN-17 Antagonist / Unkown
HY-157422 CSF1R-IN-19 Inhibitor / Unkown
HY-157996 CSF1R-IN-21 Inhibitor / Unkown
HY-158050 PXB17 Inhibitor / Unkown
HY-158148 CSF1R-IN-23 Inhibitor / Unkown
HY-158363 CSF1R-IN-25 Inhibitor / Unkown
HY-161084 CSF1R-IN-18 Inhibitor / Unkown
HY-162309 CSF1R-IN-20 Inhibitor / Unkown
HY-162415 CSF1R-IN-22 / Unkown
HY-168954 CSF1R-IN-26 / Unkown
HY-176194 Antifibrotic agent 1 / Unkown
HY-183569 CSF1R-IN-27 Inhibitor / Unkown
HY-183931 NPA101.3 Inhibitor / Unkown
HY-187340 CSF1R/c-Kit-IN-1 Inhibitor / Unkown
HY-187341 CSF1R/c-Kit-IN-2 Inhibitor / Unkown
HY-187462 Kit-IN-1 Inhibitor / Unkown
HY-RS03229 Csf1r Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03230 Csf1r Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-13493A AC710 Mesylate Inhibitor / Unkown
HY-164529 SJ-C1044 Inhibitor 98.63% Unkown
HY-174606 Human IL34 mRNA / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990125 Anti-Mouse CSF1R/CD115 Antibody (AFS98) 99.38% Unkown
HY-P990849 Anti-CSF1R/CD115 Antibody (2-4A5-4) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CSF1R NCBI NCBI:1436