MIA - MIA SH3 domain containing Gene

Also Known as CD-RAP

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8190

About MIA

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:40,775,160-40,777,490 (from NCBI)

This gene has 7 transcripts (splice variants), 163 orthologues and 10 paralogues. Biased expression in stomach (RPKM 20.5), salivary gland (RPKM 4.7) and 2 other tissues.

Summary

Predicted to enable growth factor activity. Predicted to be involved in extracellular matrix organization. Predicted to act upstream of or within cell-matrix adhesion. Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

MIA Products (2)

mRNA Protein Name
NM_001202553.2 NP_001189482.1 melanoma-derived growth regulatory protein precursor
NM_006533.4 NP_006524.1 melanoma-derived growth regulatory protein precursor

MIA Protein Structure

SH3_2

SH3_2: Variant SH3 domain (48 - 110)

  • 0
  • 100
  • 131 a.a.
Protein Preferred Names Protein Names

melanoma-derived growth regulatory protein

  • melanoma inhibitory activity

Recombinant MIA Proteins

Cat. No. Product Name Accession Purity
HY-P70846 MIA Protein, Human (His) Q16674 (G25-Q131) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P70846A MIA Protein, Human (N-His) Q16674 (G25-Q131) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Melanoma

  • Malignant Melanoma

  • Cutaneous Melanoma

  • Naevocarcinoma

  • Malignant Melanomas
Familial Isolated Hypoparathyroidism

  • Fih
Melanoma, Uveal

  • Uveal Melanoma

  • Choroidal Melanoma

  • Melanoma Of Uvea

  • Iris Melanoma

  • Malignant Melanoma Of Choroid

  • Malignant Melanoma Of Iris
Melanoma, Cutaneous Malignant 1

  • Familial Melanoma

  • Melanoma, Cutaneous Malignant, Susceptibility To, 1

  • Melanoma, Malignant

  • CMM1

  • Melanoma, Cutaneous Malignant

  • Cmm

  • Familial Atypical Mole-Malignant Melanoma Syndrome

  • Fammm

  • Melanoma, Familial

  • Mlm

  • Dysplastic Nevus Syndrome, Hereditary

  • Dns

  • B-K Mole Syndrome

  • Melanoma, Cutaneous Malignant, 1

  • Malignant Melanoma, Cutaneous

  • Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1

  • Dysplastic Nevus Syndrome

  • Cutaneous Melanoma

  • Familial Atypical Mole Melanoma Syndrome

  • Hereditary Melanoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-130149 Adagrasib Inhibitor 99.96% Unkown

Clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Phase
HY-13594 Chlorin e6 99.51% Phase 3
HY-112089 Naporafenib Inhibitor 99.92% Phase 3
HY-160023 Elisrasib 99.68% Phase 2
HY-17617 Nastorazepide 99.95% Phase 2
HY-145622 Mecbotamab vedotin Inhibitor 99.11% Phase 2
HY-13323 CX-5461 Inhibitor 99.67% Phase 1
HY-145926 MRTX0902 Inhibitor 99.67% Phase 1
HY-148012 SOP1812 98.46% Phase 1

Pre-clinical Phase

Bioactive Molecules (133)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13323A CX-5461 dihydrochloride Inhibitor 99.41% Unkown
HY-100367 ES 936 Inhibitor 98.66% Unkown
HY-33878 2-PPA Inhibitor 99.98% Unkown
HY-164899 2A3 99.92% Unkown
HY-N0841 Bruceine A 99.89% Unkown
HY-145321 TMX-4100 Inhibitor 98.26% Unkown
HY-156716 MASTL-IN-2 Inhibitor 98.89% Unkown
HY-112776A BN82002 hydrochloride Inhibitor 99.36% Unkown
HY-128522 ARS-1323-alkyne Inhibitor 99.59% Unkown
HY-114189 GW284543 Inhibitor 99.94% Unkown
HY-165245 SBI-183 Inhibitor 99.8% Unkown
HY-W115529 Geranic acid Inhibitor 90.0% Unkown
HY-144310 DX3-213B Inhibitor 99.68% Unkown
HY-155874 ZNL-05-044 Inhibitor 99.11% Unkown
HY-177106 ADT-1004 Inhibitor 98.16% Unkown
HY-141477 RM-018 Inhibitor 95.95% Unkown
HY-146459 Akt1-IN-1 Inhibitor 99.77% Unkown
HY-155356 YN14 Degrader 99.08% Unkown
HY-157762 GPX4-IN-9 99.18% Unkown
HY-162014 WDR5 degrader-1 Degrader 98.00% Unkown
HY-154313 Spiclomazine Inhibitor 99.56% Unkown
HY-162629 LDHA-IN-7 Inhibitor 99.59% Unkown
HY-163299 pan-KRAS-IN-5 96.70% Unkown
HY-178194 SHY-855 Inhibitor 98.54% Unkown
HY-N8284 Tomentosin 98.95% Unkown
HY-W140346 Copper(II) pyrithione Inhibitor 97.62% Unkown
HY-112776 BN82002 Inhibitor / Unkown
HY-137046 Nek2-IN-4 / Unkown
HY-153090 Transketolase-IN-4 Inhibitor 99.29% Unkown
HY-161618 MJ04 Inhibitor 98.08% Unkown
HY-161767 JWJ-01-306 Inhibitor / Unkown
HY-176798 NCI-006 98.73% Unkown
HY-178211 SHY-867 Inhibitor 99.66% Unkown
HY-P11781B Cys-HW12 TFA 87.29% Unkown
HY-146544 KRAS inhibitor-14 Inhibitor / Unkown
HY-146546 KRAS inhibitor-16 Inhibitor / Unkown
HY-108436 Deltazinone 1 Inhibitor 98.79% Unkown
HY-111033 RO5068760 / Unkown
HY-114189A GW284543 hydrochloride Inhibitor / Unkown
HY-120825 QD 232 / Unkown
HY-120966 NCX 2121 Inhibitor / Unkown
HY-122152 Spiclomazine hydrochloride Inhibitor / Unkown
HY-123009 KCN1 / Unkown
HY-123597 NSC 109555 / Unkown
HY-125472 LC-1028 Inhibitor / Unkown
HY-142946 KRAS G12C inhibitor 44 Inhibitor / Unkown
HY-144311 OXPHOS-IN-1 Inhibitor / Unkown
HY-146475 KRAS inhibitor-17 Inhibitor / Unkown
HY-146476 KRAS inhibitor-18 Inhibitor / Unkown
HY-146533 KRAS inhibitor-12 Inhibitor / Unkown
HY-146537 KRAS G12C inhibitor 47 Inhibitor / Unkown
HY-146543 KRAS inhibitor-13 Inhibitor / Unkown
HY-146545 KRAS inhibitor-15 Inhibitor / Unkown
HY-147838 Nampt-IN-9 Inhibitor / Unkown
HY-149076 hGAPDH-IN-1 / Unkown
HY-149510 MET/PDGFRA-IN-1 / Unkown
HY-149511 MET/PDGFRA-IN-2 / Unkown
HY-149607 SHP2-IN-22 Inhibitor / Unkown
HY-150400 XF056-132 free base Degrader / Unkown
HY-150400A XF056-132 Degrader / Unkown
HY-151968 KRAS G12C inhibitor 57 Inhibitor / Unkown
HY-153505 ADAMTS-4/5-IN-1 Inhibitor / Unkown
HY-155065 SB-1295 / Unkown
HY-155356A YN14 (mixture of diastereomers) / Unkown
HY-156549 KRAS G12C inhibitor 61 Inhibitor / Unkown
HY-159511 Hedgehog IN-7 Inhibitor / Unkown
HY-159570 XD2-149 / Unkown
HY-159577 Nic-15 Modulator / Unkown
HY-161320 EGFR-IN-105 / Unkown
HY-161425 Antitumor agent-149 Inducer / Unkown
HY-161858 EpskA21 / Unkown
HY-162281 PROTAC SOS1 degrader-6 / Unkown
HY-162627 LDHA-IN-6 Inhibitor / Unkown
HY-162763 FLQY2 Inducer / Unkown
HY-162873 MEK/RAF-IN-1 Inhibitor / Unkown
HY-164445 STAT3-IN-32 Inhibitor / Unkown
HY-168577 KRAS G12D inhibitor 25 / Unkown
HY-168716 SOS1-IN-17 Inhibitor / Unkown
HY-170550 KRAS G12C inhibitor 69 Inhibitor / Unkown
HY-170958 Scr-IN-1 / Unkown
HY-170965 Anticancer agent 264 Inhibitor / Unkown
HY-171745 ATR-IN-32 Inhibitor / Unkown
HY-172210 DDO-8958 Inducer / Unkown
HY-172259 Toyaburgine Inhibitor / Unkown
HY-173047 KRASG12C IN-15 Inhibitor / Unkown
HY-173145 CD13-IN-1 Inhibitor / Unkown
HY-173250 YN14-H / Unkown
HY-173253 E3 Ligase Ligand-linker Conjugate 173 / Unkown
HY-173477 JR5-26B Inducer / Unkown
HY-175230 ZG-2492 / Unkown
HY-175326 SOS1-IN-21 Inhibitor / Unkown
HY-179119 AB19 Inhibitor / Unkown
HY-179157 MA203 / Unkown
HY-179158 CHK1-IN-15 Ligand / Unkown
HY-179577 PIN1 degrader-3 Degrader / Unkown
HY-181071 POLRMT-IN-3 / Unkown
HY-181072 POLRMT-IN-4 Inhibitor / Unkown
HY-181913 KRAS G12C-IN-76 Inhibitor / Unkown
HY-181965 KRAS G12C-IN-78 Inhibitor / Unkown
HY-182044 MRTX849-amide-C4-(o)-carborane / Unkown
HY-183257 ATI-1 / Unkown
HY-183674 MEK-IN-10 / Unkown
HY-183786 Anticancer agent 327 / Unkown
HY-183984 G-quadruplex ligand 6 Ligand / Unkown
HY-184148 PFKFB3-IN-3 Inhibitor / Unkown
HY-184245 Hsp90-IN-48 Inhibitor / Unkown
HY-184708 Les-6666 / Unkown
HY-184984 SN-38-A2 Degrader / Unkown
HY-D2380 H2S probe 1 / Unkown
HY-DY1092 Chlorin e6 (solution) / Unkown
HY-N17236 Forsyshiyanine A Inhibitor / Unkown
HY-N19463 Dicatenarin / Unkown
HY-P10783 BGC0222 Modulator / Unkown
HY-P11781 HW12 Control / Unkown
HY-P11781A Cys-HW12 / Unkown
HY-P2698 1-Alaninechlamydocin / Unkown
HY-RS08419 MIA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08420 MIA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08421 MIA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W100150 N-((6-Methylpyridin-2-yl)carbamothioyl)benzamide / Unkown
HY-141652 N-2-Azidoethyl betulonamide / Unkown
HY-160121 Patrinoside aglucone Inhibitor / Unkown
HY-164039 Talorasib / Unkown
HY-170527 Anticancer agent 260 / Unkown
HY-181250 SHP2-IN-46 Inhibitor / Unkown
HY-183400 BIM-46174 / Unkown
HY-184378 MDB5 / Unkown
HY-50693 5-CITEP / Unkown
HY-RS16950 Mia Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19362 Otor Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21376 Mia2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23393 Mia Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27895 Mia2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MIA RGD RGD:620883
Mus musculus MIA MGD MGI:109615
Others MIA NCBI