A-1592668
A-1592668 is a selective CDK9 inhibitor. A-1592668 induces Apoptosis. A-1592668 plus Venetoclax (HY-15531) co-treatment inhibits the growth of Jeko-1 tumors.
For research use only. We do not sell to patients.
- CAS No.: 1628314-13-5
- Formula: C26H27F2N3O3
- Molecular Weight:467.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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CDK9 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MV4-11 | IC50 |
138 nM
Compound: 63; A-1592668
|
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 24 hrs by Cell-Titer Glo assay
Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability incubated for 24 hrs by Cell-Titer Glo assay
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[PMID: 32866383] |
Chemical Information
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CAS No. 1628314-13-5
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Molecular Weight 467.51
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Formula C26H27F2N3O3
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SMILES
FC1=CN=C(NC(C2=CCN([C@@H]3CC[C@H](CC3)C(O)=O)CC2)=C4)C4=C1C5=C(C=CC(F)=C5)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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