DSS30
DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid (Aβ) secretion by inhibiting amyloid precursor protein lyase 1 (BACEl) phosphorylation. DSS30 can be used in the study of neurodegenerative diseases such as Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 883027-32-5
- Formula: C16H14ClNO3S2
- Molecular Weight:367.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DSS30 (50 μM, 2 hours) inhibits the activity of the P25/CDK5 complex by up to 50% and the phosphorylation of BACE1 or Tau[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Expressed P25 PC12tet-off cell lines
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Concentration:50 μM
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Incubation Time:8 hours
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Result:Inhibited BACE1 phosphorylation by 12%.
Chemical Information
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CAS No. 883027-32-5
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Molecular Weight 367.87
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Formula C16H14ClNO3S2
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SMILES
CC1=C(S(NC2=CC=CC=C2OC)(=O)=O)SC(C=C3)=C1C=C3Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DSS30 Related Classifications
HY-147387 Related Classifications
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