Cdc7-IN-1
Based on 1 publication(s) in Google Scholar
Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death.
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- 純度: 99.32%
- CAS 番号: 1402055-25-7
- 分子式: C21H16ClN3O4
- 分子量:409.82
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Cdc7-IN-1
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生物活性
IC50: 0.6 nM (Cdc7, at 1 mM ATP)[1]
化学情報
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CAS 番号 1402055-25-7
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性状 Solid
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分子量 409.82
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分子式 C21H16ClN3O4
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Color Light yellow to yellow
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SMILES
O=C1C(C(OCC)=O)=C(NC2=C(Cl)C=CC=C2)O/C1=C\C3=CNC4=C3C=CC=N4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Publications (1)
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Journal Impact Factor
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Most Recent
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Vet Microbiol
Phosphorylation of T425 and methylation of R426 synergistically regulate IBDV VP1 function and viral replication. [Abstract]2026 Feb:313:110871. PMID: 41506171
溶剤 & 溶解度
DMSO : 5.2 mg/mL (12.69 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4401 mL | 12.2005 mL | 24.4010 mL | 61.0024 mL |
| 5 mM | 0.4880 mL | 2.4401 mL | 4.8802 mL | 12.2005 mL | |
| 10 mM | 0.2440 mL | 1.2200 mL | 2.4401 mL | 6.1002 mL |
Cdc7-IN-1 関連分類
HY-101523 関連分類
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