DiPT-4
DiPT-4 is a dual TOP1/PARP1 inhibitor that induces massive DNA double-strand breaks (DSBs), cell cycle arrest, and apoptosis in cancer cells. DiPT-4 has the potential to overcome cancer drug resistance.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3052259-89-6
- 分子式: C32H22FN5O4S
- 分子量:591.61
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Topoisomerase アイソフォーム固有の製品をすべて表示
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生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
4 μM
Compound: DiPT-4
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Cytotoxicity against human HCT-116 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human HCT-116 cells incubated for 72 hrs by MTT assay
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[PMID: 37406384] |
| MIA PaCa-2 | IC50 |
4.5 μM
Compound: DiPT-4
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Cytotoxicity against human MIA PaCa-2 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human MIA PaCa-2 cells incubated for 72 hrs by MTT assay
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[PMID: 37406384] |
| PANC-1 | IC50 |
4 μM
Compound: DiPT-4
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Cytotoxicity against human PANC-1 cells incubated for 72 hrs by MTT assay
Cytotoxicity against human PANC-1 cells incubated for 72 hrs by MTT assay
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[PMID: 37406384] |
化学情報
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CAS 番号 3052259-89-6
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分子量 591.61
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分子式 C32H22FN5O4S
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SMILES
O=C1N(CC2=NN=C(SCCN3C(C4=CC=CC5=CC=CC(C3=O)=C45)=O)O2)N=C(CC6=CC=C(F)C=C6)C7=C1C=CC=C7
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DiPT-4 関連分類
HY-149348 関連分類
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