DSS30
DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid (Aβ) secretion by inhibiting amyloid precursor protein lyase 1 (BACEl) phosphorylation. DSS30 can be used in the study of neurodegenerative diseases such as Alzheimer's disease.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 883027-32-5
- 分子式: C16H14ClNO3S2
- 分子量:367.87
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
DSS30 (50 μM, 2 hours) inhibits the activity of the P25/CDK5 complex by up to 50% and the phosphorylation of BACE1 or Tau[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Expressed P25 PC12tet-off cell lines
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Concentration:50 μM
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Incubation Time:8 hours
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Result:Inhibited BACE1 phosphorylation by 12%.
化学情報
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CAS 番号 883027-32-5
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分子量 367.87
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分子式 C16H14ClNO3S2
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SMILES
CC1=C(S(NC2=CC=CC=C2OC)(=O)=O)SC(C=C3)=C1C=C3Cl
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DSS30 関連分類
HY-147387 関連分類
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