DSS30
DSS30 is a P25/CDK5 inhibitor that reduces β-amyloid (Aβ) secretion by inhibiting amyloid precursor protein lyase 1 (BACEl) phosphorylation. DSS30 can be used in the study of neurodegenerative diseases such as Alzheimer's disease.
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- CAS No.: 883027-32-5
- 화학식: C16H14ClNO3S2
- 분자량:367.87
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocol
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
DSS30 (50 μM, 2 hours) inhibits the activity of the P25/CDK5 complex by up to 50% and the phosphorylation of BACE1 or Tau[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Expressed P25 PC12tet-off cell lines
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Concentration:50 μM
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Incubation Time:8 hours
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Result:Inhibited BACE1 phosphorylation by 12%.
Chemical Information
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CAS No. 883027-32-5
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분자량 367.87
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화학식 C16H14ClNO3S2
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SMILES
CC1=C(S(NC2=CC=CC=C2OC)(=O)=O)SC(C=C3)=C1C=C3Cl
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DSS30 Related Classifications
HY-147387 Related Classifications
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