SLM6
SLM6 is a sangivamycin-like molecule. SLM6 is a CDK9 inhibitor. SLM6 inhibits CDK9/cyclin K and CDK9/cyclin T1 kinase activity with IC50s of 280 nM and 133 nM, respectively. SLM6 also inhibits CDK1/cyclin B and CDK2/ cyclin A with IC50s of less than 300 nM. SLM6 induces apoptosis in multiple myeloma (MM) cells.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 22242-91-7
- 화학식: C12H17N7O4
- 분자량:323.31
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CDK9/cyclinT1 133 nM (IC50) |
Chemical Information
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CAS No. 22242-91-7
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분자량 323.31
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화학식 C12H17N7O4
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SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=C(C(NN)=N)C3=C(N)N=CN=C32)O1
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)