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Cat. No.: HY-14541S3

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Olanzapine-d₁₅

(Synonyms: LY170053-d₁₅)

Olanzapine-d₁₅ (LY170053-d₁₅) is the deuterium labeled Olanzapine (HY-14541). Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (K_i = 7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (K_i = 11 to 31 nM), muscarinic M1-5 (K_i = 1.9-25 nM), and adrenergic α1 receptor (K_i = 19 nM). Olanzapine is an atypical antipsychotic.

For research use only. We do not sell to patients.

CAS No.: 1252611-25-8
Formula: C₁₇H₅D₁₅N₄S
Molecular Weight:327.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Olanzapine-d₁₅ Chemical Structure

CAS No.: 1252611-25-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All mAChR Isoforms :

All Dopamine Receptor Isoforms :

All 5-HT Receptor Isoforms :

All Adrenergic Receptor Isoforms :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1252611-25-8
Unlabeled Cas 132539-06-1
Molecular Weight 327.52
Formula C₁₇H₅D₁₅N₄S
SMILES

CC1=CC2=C(S1)NC3=C([2H])C([2H])=C([2H])C([2H])=C3N=C2N4C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C4([2H])[2H])C([2H])([2H])[2H]
Synonyms

LY170053-d₁₅
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.