ROCK/HDAC-IN-2
ROCK/HDAC-IN-2 (Compound C-9) is a ROCK/HDAC inhibitor, with IC50 values of 0.185 µM, 0.8 µM, and 0.7 µM for HDAC6, ROCK1, and ROCK2, respectively. ROCK/HDAC-IN-2 can induce apoptosis and changes in mitochondrial membrane potential in cancer cells, demonstrating significant antitumor activity. ROCK/HDAC-IN-2 can be used in the research of pancreatic ductal adenocarcinoma (PDAC) and triple-negative breast cancer (TNBC).
For research use only. We do not sell to patients.
- Formula: C22H32N4O4S
- Molecular Weight:448.58
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC6 0.185 μM (IC50) |
ROCK1 0.8 μM (IC50) |
ROCK2 0.7 μM (IC50) |
Chemical Information
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Molecular Weight 448.58
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Formula C22H32N4O4S
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SMILES
O=C(NO)CCCCCCCN1CCCN(CC1)S(=O)(C2=CC=CC3=C2C=CN=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ROCK/HDAC-IN-2 Related Classifications
HY-172177 Related Classifications
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