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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3667 Results for "
anticancer activity
" in MedChemExpress (MCE) Product Catalog:
Products (3667)
3667 Results for "anticancer activity" in MCE Product Catalog:
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20 Cited Publications
Synonyms: GSK2126458; GSK458
Omipalisib (GSK2126458) is an orally active and highly selective inhibitor of PI3K with Kis of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM for p110α/β/δ/γ, mTORC1/2, respectively. Omipalisib has anti-cancer activity .
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Halofuginone hydrochloride (RU-19110 hydrochloride), a Febrifugine derivative, is a competitive prolyl-tRNA synthetase inhibitor with a Ki of 18.3 nM . Halofuginone hydrochloride is a specific inhibitor of type-I collagen synthesis and attenuates osteoarthritis (OA) by inhibition of TGF-β activity . Halofuginone hydrochloride is also a potent pulmonary vasodilator by activating Kv channels and blocking voltage-gated, receptor-operated and store-operated Ca 2+ channels. Halofuginone hydrochloride has anti-malaria, anti-inflammatory, anti-cancer, anti-fibrosis effects .
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19 Cited Publications
Synonyms: Astragaline; 3-Glucosylkaempferol; Kaempferol 3-β-D-glucopyranoside
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19 Cited Publications
Art. -Nr.: HY-N0279
CAS. Nr.: 18956-16-6
Synonyms: Cardamomin; Alpinetin chalcone
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19 Cited Publications
Synonyms: L-6-Diazo-5-oxonorleucine; DON
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine; DON) is a glutamine antagonist that irreversibly inhibits the catabolic effect of glutamine. 6-Diazo-5-oxo-L-nor-Leucine shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. 6-Diazo-5-oxo-L-nor-Leucine also possesses antibacterial and antiviral activity .
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17 Cited Publications
Target:
Forschungsgebiete:
CB-6644 is a selective inhibitor of RUVBL1/2 complex with anti-cancer activity. CB-6644 blocks the ATPase activity of RUVBL1/2 with an IC50 of 15 nM .
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17 Cited Publications
Target:
Forschungsgebiete:
XMD8-92 is a potent ERK5 (BMK1)/BRD4 inhibitor with Kds of 80 and 190 nM, respectively. XMD8-92 inhibits DCAMKL2, PLK4 and TNK1 with Kds of 190, 600 and 890 nM, respectively. Anti-cancer activity .
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16 Cited Publications
Gamitrinib TPP hexafluorophosphate is a Gamitrinib (GA) mitochondrial matrix inhibitor. Gamitrinib TPP hexafluorophosphate is a mitochondrial targeted HSP90 inhibitor with anti-cancer activity.
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16 Cited Publications
Synonyms: (S)-(+)-[6]Gingerol
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Category:
Xanthones Phenols Polyphenols Anemarrhena asphodeloides Bunge Plants Liliaceae Extract Disease Research Fields Cancer
Target:
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Category:
Infection Flavonoids Chalcones Humulus lupulus L. Moraceae Extract Phenols Polyphenols Plants Disease Research Fields
Target:
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16 Cited Publications
Synonyms: 5,7-Dihydroxy-4'-methoxyflavone
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16 Cited Publications
PI3K/AKT-IN-1 is an effective PI3K/AKT dual inhibitor (IC50 of 6.99, 4.01 and 3.36 μM for PI3Kγ, PI3Kδ and AKT, respectively). PI3K/AKT-IN-1 has anticancer activity and acts by inhibiting PI3K/AKT axis and inducing caspase 3 dependent apoptosis .
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15 Cited Publications
Target:
Forschungsgebiete:
BMH-21 is a first-in-class DNA intercalator which inhibits RNA polymerase I (Pol I) transcription. BMH-21 possesses anticancer activity .
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15 Cited Publications
Art. -Nr.: HY-N0720
CAS. Nr.: 41060-15-5
Category:
Flavonoids Phenols Polyphenols Leguminosae Extract Psoralea corylifolia L. Plants Disease Research Fields Cancer Isoflavones
Target:
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15 Cited Publications
Synonyms: Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
