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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
58 Results for "
H2O2-inducible
" in MedChemExpress (MCE) Product Catalog:
Products (58)
58 Results for "H2O2-inducible" in MCE Product Catalog:
20
Category:
Natural Products Neurological Disease Orchidaceae Extract Gastrodia elata Bl. Anti-aging Phenols Plants Disease Research Fields Inflammation/Immunology
Target:
15
15 Cited Publications
Synonyms: Luteolin 7-glucoside; Luteolin 7-O-β-D-glucoside
13
13 Cited Publications
Target:
Research Areas:
CORM-401 is an oxidant-sensitive CO-releasing molecule. CORM-401 induces NO increase in the regulation of endothelial calcium signalling. CORM-401 reduces TNF-α/CHX and H2O2-induced ROS production. CORM-401 uncouples mitochondrial respiration and inhibits glycolysis .
6
Category:
Flavonoids Monophenols Neurological Disease Flavones Phenols Plants Other Families Extract Disease Research Fields Inflammation/Immunology
Target:
4
4 Cited Publications
Cat. No.: HY-N0615
CAS No.: 80418-24-2
Synonyms: Sanchinoside R1; Sanqi glucoside R1
3
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H2O2-induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation .
2
2 Cited Publications
Cat. No.: HY-N0515
CAS No.: 945619-74-9
2
2 Cited Publications
Synonyms: Luteolin 7-glucoside (Standard); Luteolin 7-O-β-D-glucoside (Standard)
1
1
1 Cited Publications
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Research Areas:
IM-54 is a selective inhibitor of oxidative stress-induced necrosis. IM-54 shows potent inhibitory activity against H2O2-induced necrosis. IM-54 acts as a potential cardioprotective agent and biological tool for investigating the molecular mechanisms of cell death .
1
1 Cited Publications
Cat. No.: HY-N2565
CAS No.: 88515-58-6
Category:
Infection Triterpenes Terpenoids Rosaceae Extract Potentilla anserina Linn. Plants Disease Research Fields
Target:
Cat. No.: HY-N2410
CAS No.: 66648-43-9
Synonyms: N-feruloyltyramine; Moupinamide
Synonyms: EZM-K
Target:
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology Cancer
Ezetimibe ketone is an orall active Nrf2 activator and ROS inhibitor. Ezetimibe ketone attenuates H2O2-induced reactive oxygen species production and reduces H2O2-induced apoptosis in renal tubular epithelial cells. Ezetimibe ketone suppresses renal tubular injury and inflammation .
Cat. No.: HY-P5883
CAS No.: 2126166-03-6
Synonyms: tatM2NX
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Research Areas:
Cat. No.: HY-W423191
CAS No.: 534-42-9
Synonyms: 4-O-α-D-Glucopyranosyl-D-gluconic acid
Cat. No.: HY-164926
CAS No.: 2640677-68-3
Target:
Research Areas:
PARP1-IN-33 (Example 6) is a PARP1 inhibitor (IC50: 0.41 nM). PARP1-IN-33 has retinal cytoprotective effect, with an EC50 of 0.02 nM (inhibition on MTS activity of H2O2 induced human retinal pigment epithelial cell) .
Cat. No.: HY-N5021
CAS No.: 184840-84-4
Synonyms: AHSYB
Category:
Quinones Carthamus tinctorius L. Simple Phenylpropanols Phenols Polyphenols Benzene Quinones Phenylpropanoids Plants Compositae Extract
Target:
Cat. No.: HY-124834
CAS No.: 75483-04-4
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Research Areas:
Nrf2 activator-10 (Compound AI-1) is a PI3K-dependent inducer for antioxidant response element (ARE) (EC50 is 2.7 μM) and an activator for Nrf2. Nrf2 activator-10 modifies Keap1, blocks Cul3-Keap1 ubiquitin ligase complex, activates the transcription of Nrf2. Nrf2 activator-10 protects cells from H2O2-induced apoptosis.
Category:
Cat. No.: HY-N0515R
CAS No.: 945619-74-9
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
