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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
enteric infection
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "enteric infection" in MCE Product Catalog:
4
4 Cited Publications
CP-724714 is an orally active and selective HER2 tyrosine kinase inhibitor with an IC50 of 10 nM. CP-724714 inhibits HER2 receptor autophosphorylation and blocks the downstream Ras-Raf-Mek-Erk signaling pathway, thereby inducing cell cycle arrest and apoptosis in tumor cells. CP-724714 exhibits antiviral activity and inhibits various porcine diarrheal coronaviruses, including SADS-CoV (IC50 of 0.91 μM). CP-724714 is an inhibitor of the hepatic transport receptors OATP1B1/MDR1/BSEP, and can enter hepatocytes via active uptake and trigger the accumulation of drugs and bile acids within hepatocytes. CP-724714 can be used in research related to HER2-overexpressing breast cancer and porcine diarrheal coronavirus infection .
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Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery .
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Cardiovascular Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-N12323
CAS No.: 32581-31-0
Target:
Cat. No.: HY-P99146
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
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Sulfaguanidine (Standard) is the analytical standard of Sulfaguanidine. This product is intended for research and analytical applications. Sulfaguanidine is an orally active antimicrobial agent/antibiotic of sulfonamide class. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery .
Cat. No.: HY-B1267S1
Cat. No.: HY-W071746R
CAS No.: 506-21-8
Synonyms: Linoelaidic acid (Standard)
Cat. No.: HY-P10980
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Research Areas:
Cat. No.: HY-171983
CAS No.: 2724259-07-6
RSV-IN-13 (compound 24) is a selective RSV fusion protein inhibitor with antiviral activity. RSV-IN-13 has an EC50 of 444.2 nM against RSV A2 strain and a CC90 of 23.7 μM in HepG2 cells. RSV-IN-13 can block the virus from entering host cells. RSV-IN-13 can be used to study RSV infection .
Cat. No.: HY-126770
CAS No.: 114301-25-6
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Target:
Rhizocticin A is a natural antifungal phosphonate oligopeptide produced by Bacillus subtilis ATCC 6633 that targets threonine synthase (TS). Rhizocticin A enters sensitive fungal cells via oligopeptide transport systems and releases its active (S,Z)-APPA moiety through hydrolysis by intracellular peptidases. Rhizocticin A exhibits antifungal activity against yeasts and filamentous fungi, with a MIC of 0.35 μg/mL against Saccharomyces cerevisiae, Saccharomycopsis lipolytica and Schizosaccharomyces pombe. Rhizocticin A can be used in studies related to fungal infections, oligopeptide transport and threonine biosynthesis .
Cat. No.: HY-169977
CKP-25 is an inhibitor for the interaction between Spike RBD-ACE2, that prevents the virus from entering the host cell, thereby reducing the replication and virus infection. CKP-25 inhibits SARS-CoV-2 with IC50 of 3.5 μM in Vero E6 cell .
Cat. No.: HY-P10970
CAS No.: 1539295-33-4
Cat. No.: HY-L002
4,884 compounds
An infection occurs when another organism enters a person’s body and causes disease. The organisms that cause infections are very diverse and can include things like viruses, bacteria, fungi, and parasites. The immune system is an effective barrier against infectious agents.
MCE provides a unique collection of 4,884 anti-infective compounds with anti-bacterial, anti-viral, anti-fungal and anti-parasite activities that can be used for drug screening and other research in anti-microbial area.
Cat. No.: HY-182816
CAS No.: 3080330-34-0
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Topoisomerase I-IN-22 is an inhibitor of MRSA DNA Topoisomerase I with an IC50 of 0.85 μg/mL. Topoisomerase I-IN-22 can specifically disrupt the cell membrane structure of MRSA, enter the interior of bacteria and inhibit the activity of DNA Topoisomerase I, thereby interfering with the processes of DNA replication and transcription. Topoisomerase I-IN-22 can be used for the research of MRSA infection .
Cat. No.: HY-14674A
CAS No.: 543681-31-8
CP-724714 succinate is an orally active and selective HER2 tyrosine kinase inhibitor with an IC50 of 10 nM. CP-724714 succinate inhibits HER2 receptor autophosphorylation and blocks the downstream Ras-Raf-Mek-Erk signaling pathway, thereby inducing cell cycle arrest and apoptosis in tumor cells. CP-724714 succinate exhibits antiviral activity and inhibits various porcine diarrheal coronaviruses, including SADS-CoV (IC50 of 0.91 μM). CP-724714 succinate is an inhibitor of the hepatic transport receptors OATP1B1/MDR1/BSEP, and can enter hepatocytes via active uptake and trigger the accumulation of drugs and bile acids within hepatocytes. CP-724714 succinate can be used in research related to HER2-overexpressing breast cancer and porcine diarrheal coronavirus infection .
Cat. No.: HY-L181
30,147 compounds
Bioactive small molecules are important sources of lead compounds and effective tools for drug screening. Because the target of active small molecules is clear, it is conducive to the study of mechanism. In addition, due to the large structural differences between the individual active molecules, it is easier to obtain a greater variety of lead compounds.
MCE integrates the Bioactive Compound Library (HY-L001) and Novel Bioactive Compound Library (HY-L111) to form the Bioactive Compound Library Max. Bioactive Compound Library Max contains novel active small molecules, molecules that have entered the clinical stage and the market, and small molecules that have been verified by cell experiments or biochemical experiments, which fundamentally expands the number of compound libraries in the library and improves the structural diversity, and is an effective tool to start drug screening and mechanism research.
MCE can provide a library of 30,147 mitophagy compounds, which can be used for drug development and mechanism research in cancer, immunity, infection and other hot research fields.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
