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sulfate

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17565

Bleomycin sulfate Maximum Cited Publications 191 Publications Verification Bleomycin sulfate	DNA/RNA Synthesis Antibiotic	Cancer
Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic .

HY-B1370

Hydroxychloroquine sulfate 85+ Cited Publications HCQ sulfate	Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection Cancer
Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro .

HY-13780

Vinblastine sulfate 15+ Cited Publications Vincaleukoblastine sulfate salt	Microtubule/Tubulin nAChR Autophagy	Cancer
Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC₅₀ of 8.9 μM.

HY-Y1878

Copper(Ⅱ) sulfate 3 Publications Verification Cupric sulfate	Environmental Pollutants Biochemical Assay Reagents	Others
Copper(Ⅱ) sulfate (Cupric sulfate) is an inorganic compound that is a source of copper ions. Copper(Ⅱ) sulfate forms coordination compounds through the coordination of copper ions with ligands. Copper(Ⅱ) sulfate can be used for various enzymatic studies and material synthesis .

HY-111431

p-Cresyl sulfate 5+ Cited Publications p-Tolyl sulfate	JNK p38 MAPK Reactive Oxygen Species (ROS)	Metabolic Disease
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate shows antiproliferation activity. p-Cresyl sulfate increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate activates the JNK and p38 MAPK signaling pathways .

HY-N0716B

Berberine sulfate 75+ Cited Publications Natural Yellow 18 sulfate	Antibiotic Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Parasite Apoptosis PI3K Akt Caspase JNK AP-1 NF-κB	Infection Cardiovascular Disease Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability .

HY-113416

Dehydroepiandrosterone sulfate 5 Publications Verification DHEA sulfate; Prasterone sulfate	GABA Receptor Sigma Receptor iGluR PPAR NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABA_A receptor and agonist activity of σ₁ receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABA_A receptor-mediated chloride influx, enhance NMDA receptor activity through σ₁ receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .

HY-111431A

*p-Cresyl sulfate* potassium** 5+ Cited Publications p-Tolyl sulfate potassium	Endogenous Metabolite JNK p38 MAPK	Metabolic Disease Inflammation/Immunology
p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity .

HY-B1241

Dihydrostreptomycin sulfate DHSM sulfate	Antibiotic Bacterial	Infection
Dihydrostreptomycin sulfate (DHSM sulfate) is the sulfate salt form of Dihydrostreptomycin (HY-B1241A). Dihydrostreptomycin sulfate is an aminoglycoside antibiotic with antibacterial effect against Gram-negative bacteria. Dihydrostreptomycin sulfate exhibits ototoxicity that causes irreversible damage in inner ear hair cells, leading to hearing loss .

HY-B0765

*Dehydroepiandrosterone sulfate* sodium** 5 Publications Verification DHEA sulfate sodium; Prasterone sulfate sodium	GABA Receptor Sigma Receptor iGluR PPAR NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABA_A receptor and agonist activity of σ₁ receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABA_A receptor-mediated chloride influx, enhance NMDA receptor activity through σ₁ receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .

HY-B1228

Ribostamycin sulfate 1 Publications Verification Vistamycin sulfate	Antibiotic PDI	Infection
Ribostamycin sulfate (Vistamycin sulfate) is a broad-spectrum aminoglycoside Antibiotic with bactericidal activity against Gram-positive cocci, Gram-negative cocci, bacilli, and drug-resistant strains. Ribostamycin sulfate also acts as an inhibitor of protein disulfide isomerase (PDI), with a binding constant K_D of 319 μM for bovine PDI. Ribostamycin sulfate targets bacterial 16S ribosomal RNA and the 30S ribosomal subunit, causing translational misreading and thereby inhibiting bacterial protein synthesis. Ribostamycin sulfate disrupts the integrity of bacterial cell membranes, induces membrane pore formation, and leads to bacterial death. Ribostamycin sulfate can be used in studies related to bacterial infections .

HY-17423A

Abacavir sulfate 5 Publications Verification Abacavir Hemisulfate; ABC sulfate	Reverse Transcriptase HIV Telomerase Apoptosis	Infection Cancer
Abacavir sulfate (Abacavir Hemisulfate) is a competitive, orally active nucleoside reverse transcriptase inhibitor. Abacavir sulfate can inhibits the replication of HIV. Abacavir sulfate shows anticancer activity in prostate cancer cell lines. Abacavir sulfate can trespass the blood-brain-barrier and suppresses telomerase activity .

HY-W094475C

*Magnesium sulfate* heptahydrate, for cell culture** Epsom salts, for cell culture	Environmental Pollutants Biochemical Assay Reagents	Others
Magnesium sulfate heptahydrate, for cell culture (Epsom salts, for cell culture) is a hydrate of Magnesium sulfate (HY-Y1267), suitable for cell culture .

HY-113074

Glycolithocholic acid 3-sulfate Glycolithocholate sulfate; Sulfolithocholylglycine; SLCG	HIV Endogenous Metabolite	Infection Inflammation/Immunology
Glycolithocholic acid 3-sulfate (SLCG) is a cholic acid derivative and a metabolite of glycolithocholic acid. Glycolithocholic acid 3-sulfate inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate can be used for the research of HIV infection and gallbladder disease .

HY-17624A

Framycetin sulfate 1 Publications Verification Neomycin B sulfate; Fradiomycin B sulfate	Antibiotic Bacterial	Infection
Framycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a K_i of 35 μM. Framycetin sulfate competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin sulfate inhibits hammerhead ribozyme with a K_i of 13.5 μM. Framycetin sulfate, a 5″-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections .

HY-12866A

Larotrectinib sulfate 15+ Cited Publications LOXO-101 sulfate; ARRY-470 sulfate	Trk Receptor Apoptosis	Cancer
Larotrectinib sulfate (LOXO-101 sulfate; ARRY-470 sulfate) is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors, with low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C).

HY-107813

Amikacin sulfate 25+ Cited Publications BAY 41-6551 sulfate	Bacterial Antibiotic	Infection Cancer
Amikacin sulfate (BAY 41-6551 sulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin sulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin sulfate is very active against most Gram-negative bacteria including gentamicin- and tobramycin-resistant strains. Amikacin sulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria .

HY-W051140

Silver sulfate Disilver sulfate, 99%	Environmental Pollutants Biochemical Assay Reagents	Others
Silver sulfate acts as an ethylene inhibitor and a shoot regeneration promoter. Silver sulfate promotes shoot proliferation in explants of the cherry rootstock CAB-6P. Silver sulfate is applicable to studies on the optimization of micropropagation for cherry rootstocks .

HY-50706A

Selumetinib sulfate 85+ Cited Publications AZD6244 sulfate; ARRY-142886 sulfate	MEK Apoptosis	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Selumetinib (AZD6244) sulfate is selective, non-ATP-competitive oral MEK1/2 inhibitor, with an IC₅₀ of 14 nM for MEK1. Selumetinib (AZD6244) sulfate inhibits ERK1/2 phosphorylation. Selumetinib sulfate can penetrate the blood brain barrier (BBB) .

HY-141672

*17β-Estradiol sulfate* sodium** 1 Publications Verification 17β-Estradiol 3-sulfate sodium	GABA Receptor	Neurological Disease
17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .

HY-129040A

m-Iodobenzylguanidine sulfate 1 Publications Verification MIBG sulfate; Iobenguane sulfate	Adrenergic Receptor	Cancer
m-Iodobenzylguanidine sulfate (MIBG sulfate) is an analogue of the neurotransmitter norepinephrine with antitumor activity. Radioiodinated m-Iodobenzylguanidine sulfate is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. m-Iodobenzylguanidine sulfate is a high-affinity substrate for cholera toxin that interferes with cellular mono(ADP-ribosylation) .

HY-116282M

*Dextran sulfate, low sulfate* (MW 40000)**	Bacterial	Inflammation/Immunology
Dextran sulfate, low sulfate (MW 40000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 40000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .

HY-W009439

Glucosamine 6-sulfate GlcN6P; D-Glucosamine-6-sulfate	Biochemical Assay Reagents	Others
Glucosamine 6-sulfate (GlcN6P) is an organic cofactor that splits phosphodiester bonds. Glucosamine 6-sulfate plays a variety of catalytic roles in glmS ribozymes .

HY-17657

*Androst-5-enediol sulfate* sodium** 5-Androstenediol 3-sulfate sodium	Drug Intermediate	Metabolic Disease
Androst-5-enediol sulfate (5-Androstenediol 3-sulfate) sodium salt is an adrenal Δ5-steroid sulfate that synthesized by zona reticularis of adrenal depending on the lyase and Cytochrome b5 type A (CYB5A) activity. Androst-5-enediol sulfate sodium salt is a precursor hormone and can be desulfated to produce more potent androgens, including testosterone, in peripheral tissues like skin and liver. The serum level of Androst-5-enediol sulfate sodium salt has an age-related increase .

HY-156836

Tyramine O-sulfate Tyramine sulfate	Drug Metabolite	Neurological Disease
Tyramine O-sulfate (Tyramine sulfate) is a metabolite of Tyramine (HY-W007606) formed via sulfation, which serves as a biomarker for depression. Tyramine O-sulfate can be used in the research of depression .

HY-147323

Ferulic acid 4-O-sulfate Ferulic acid 4-sulfate	Drug Metabolite	Cardiovascular Disease
Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid (HY-N0060). Ferulic acid 4-O-sulfate relaxes arteries and lowers blood pressure in mice .

HY-B1370R

*Hydroxychloroquine sulfate* (Standard)** 40+ Cited Publications HCQ sulfate (Standard)	Reference Standards Parasite Toll-like Receptor (TLR) SARS-CoV Autophagy	Infection Cancer
Hydroxychloroquine (sulfate) (Standard) is the analytical standard of Hydroxychloroquine (sulfate). This product is intended for research and analytical applications. Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro .

HY-128442

Phenyl sulfate Phenyl hydrogen sulfate	Endogenous Metabolite	Metabolic Disease
Phenyl sulfate is an orally active gut microbiota-derived metabolite. Phenyl sulfate induces albuminuria and podocyte damage in experimental models of diabetes. Phenyl sulfate can be used as a disease marker in diabetic kidney disease .

HY-100589

Isepamicin sulfate 1 Publications Verification Sch 21420 sulfate	Antibiotic Bacterial	Infection Cardiovascular Disease Neurological Disease Metabolic Disease
Isepamicin sulfate (Sch 21420 sulfate) is a broad-spectrum aminoglycoside antibiotic. Isepamicin sulfate has considerable antimicrobial activity against some Gram-negative non-fermenting bacteria that are highly resistant to antibiotics. Isepamicin sulfate inhibits writhing reactions induced by Acetic acid (HY-Y0319), regulates vascular blood flow and blood pressure, and inhibits spontaneous uterine movements. Isepamicin sulfate has antidiuretic and blood sugar-raising effects. Isepamicin sulfate can be used in seizure research .

HY-13780R

*Vinblastine sulfate* (Standard)** Vincaleukoblastine sulfate salt (Standard)	Reference Standards Microtubule/Tubulin Autophagy nAChR	Cancer
Vinblastine (sulfate) (Standard) is the analytical standard of Vinblastine (sulfate). This product is intended for research and analytical applications. Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC₅₀ of 8.9 μM.

HY-D1213

*4-Nitrocatechol sulfate* dipotassium salt** Dipotassium nitrocatechol sulfate	Biochemical Assay Reagents	Others
4-Nitrocatechol sulfate potassium salt (Dipotassium nitrocatechol sulfate) is an aromatic sulfate that can serve as a chromogenic substrate for sulfatase. 4-Nitrocatechol sulfate potassium salt can be used to determine the activities of glycosaminoglycan (GAG) degrading enzymes aryl sulfatase B and exonucleosidase .

HY-W115752

*Hydrazine sulfate* (99%)** Diamine sulfate (99%)	PEPCK Aldehyde Dehydrogenase (ALDH)	Neurological Disease Metabolic Disease Cancer
Hydrazine sulfate is an orally active PEPCK inhibitor. Hydrazine sulfate inhibits PEPCK and low-K_m ALDH. Hydrazine sulfate impairs gluconeogenesis and enhances the protective effect of energy substrates against MPP ⁺ toxicity. Hydrazine sulfate exacerbates liver damage in rats when combined with Ethanol. Hydrazine sulfate can be used in the research of shock, non-small cell lung cancer, colorectal cancer and Parkinson's disease .

HY-111431AS

*p-Cresol sulfate-d7 potassium* p-Tolyl sulfate-d7 potassium	Endogenous Metabolite	Metabolic Disease
p-Cresol sulfate-d₇ (potassium) is the deuterium labeled p-Cresyl sulfate potassium. p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin[1][2].

HY-W009454

Potassium p-nitrophenyl sulfate 4-Nitopheyl sulfate potassium	Fluorescent Dye	Others
Potassium p-nitrophenyl sulfate (4-Nitophenyl Sulfate potassium) serves as a chromogenic substrate for arylsulfatases. Potassium p-nitrophenyl sulfate releases nitrophenol under the cleavage action of arylsulfatases, and the activity of arylsulfatases can be quantitatively determined via colorimetric detection at 400 nm. Potassium p-nitrophenyl sulfate is commonly used in enzyme inhibition assays and metabolite analog-related studies .

HY-141921S

*Dehydroepiandrosterone sulfate* sodium-d6** DHEA sulfate sodium-d6; Prasterone sulfate sodium-d6	Isotope-Labeled Compounds GABA Receptor Sigma Receptor iGluR PPAR NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology
Dehydroepiandrosterone sulfate sodium salt-d₆ (DHEA sulfate sodium salt-d₆; Prasterone sulfate sodium salt-d₆) is the deuterium labeled Dehydroepiandrosterone sulfate sodium salt (HY-B0765). Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABA_A receptor and agonist activity of σ₁ receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABA_A receptor-mediated chloride influx, enhance NMDA receptor activity through σ₁ receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .

HY-N8460A

*Cortisol sulfate* sodium** 1 Publications Verification Cortisol 21-sulfate sodium	Endogenous Metabolite	Endocrinology
Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin .

HY-N0471A

L-Hyoscyamine sulfate 2 Publications Verification Daturine sulfate	mAChR	Neurological Disease
L-Hyoscyamine sulfate (Daturine sulfate), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine sulfate is a levo-isomer to Atropine (HY-B1205) .

HY-W276164

Sodium octadecyl sulfate Sodium stearyl sulfate	Biochemical Assay Reagents	Others
Sodium octadecyl sulfate (Sodium stearyl sulfate) is a long-chain alkyl sodium sulfate that functions as an emulsifier, crosslinking agent, and regulator. Sodium octadecyl sulfate has high safety, with a LD₅₀ greater than 3.00 Gm./Kg for both intraperitoneal injection in mice and oral administration in rats. Sodium octadecyl sulfate enhances continuous contraction of the gastrocnemius muscle in frogs and boosts intestinal smooth muscle activity in albino rats. However, Sodium octadecyl sulfate exerts no significant effect on isolated tortoise myocardium and does not alter the conduction function of frog sciatic nerves. Sodium octadecyl sulfate can also be used to coat the surface of starch aggregates, promote crosslinking and increase aggregate size through hydrophobic and electrostatic interactions, and further form a coexistent B-V type crystalline structure with acid-hydrolyzed gelatinized starch, thereby effectively modifying the structure and surface properties of high-starch systems .

HY-W096997A

*Sodium octyl sulfate* (SOS), 95%** Sodium capryl sulfate, 95%	Biochemical Assay Reagents	Others
Sodium octyl sulfate (SOS), 95% (Sodium capryl sulfate, 95%) is an anionic detergent and ion-pairing agent.

HY-116282P

*Dextran sulfate, high sulfate* (MW 5000)**	Bacterial	Infection Inflammation/Immunology
Dextran sulfate, high sulfate (MW 5000) is a type of dextran sulfate with a high degree of sulfation. Dextran sulfate sodium can be used to induce ulcerative colitis models, and the greater the total number of sulfur atoms, the stronger the induced toxic effect. Dextran sulfate has certain antibacterial activity, and can form the ionic cross-linking core of nanoparticles together with chitosan, serving as a highly efficient dressing material to accelerate wound healing .

HY-N8460

Cortisol sulfate Cortisol 21-sulfate	Endogenous Metabolite	Endocrinology
Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate is a specific ligand for intracellular transcortin .

HY-156836A

*Tyramine O-sulfate* sodium** Tyramine sulfate sodium	Drug Metabolite	Neurological Disease
Tyramine O-sulfate (Tyramine sulfate) sodium is a metabolite of Tyramine (HY-W007606) formed via sulfation, which serves as a biomarker for depression. Tyramine O-sulfate sodium can be used in the research of depression .

HY-116282J

*Dextran sulfate, low sulfate* (MW 5000)**	Bacterial	Inflammation/Immunology
Dextran sulfate, low sulfate (MW 5000), a biopolymer, is a sulfated polysaccharide. Dextran sulfate, low sulfate (MW 5000) has antiviral, antibacterial, anti-inflammatory, antifibrotic, and wound-healing properties. Dextran sulfate can be used as an additive in cell culture media for preventing cell aggregation and in cosmetics as a gel-forming agent .

HY-113416R

*Dehydroepiandrosterone sulfate* (Standard)** 1 Publications Verification DHEA sulfate (Standard); Prasterone sulfate (Standard)	Reference Standards GABA Receptor Sigma Receptor iGluR PPAR NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) (Standard) is the analytical standard of Dehydroepiandrosterone sulfate (HY-113416). This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABA_A receptor and agonist activity of σ₁ receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABA_A receptor-mediated chloride influx, enhance NMDA receptor activity through σ₁ receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .

HY-113323A

3-Methoxy-4-hydroxyphenylglycol sulfate HMPG sulfate; MHPG sulfate; MOPEG sulfate	Endogenous Metabolite	Neurological Disease
3-Methoxy-4-hydroxyphenylglycol sulfate (HMPG sulfate) is a metabolite of norepinephrine degradation in the brain. 3-Methoxy-4-hydroxyphenylglycol sulfate is an indicators of central nervous system noradrenergic activity. 3-Methoxy-4-hydroxyphenylglycol sulfate can be used for research of depression, chronic schizophrenia, etc .

HY-B1134A

Imazalil sulfate 1 Publications Verification Enilconazolel sulfate	Environmental Pollutants Fungal Pregnane X Receptor (PXR)	Infection
Imazalil (Enilconazole) sulfate is a fungicide. Imazalil sulfate has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil sulfate is commonly used to protect various agricultural crops against fungal attack. Imazalil sulfate induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder .

HY-113360

Chenodeoxycholic acid 3-sulfate	Endogenous Metabolite	Inflammation/Immunology
Chenodeoxycholic acid 3-sulfate is a bile acid. Chenodeoxycholic acid 3-sulfate level corresponds closely with the extent of hepatic dysfunction .

HY-B0402B

Amantadine sulfate 1-Adamantanamine sulfate; 1-Aminoadamantane sulfate	Influenza Virus Orthopoxvirus SARS-CoV Apoptosis CDK Bcl-2 Family	Infection Neurological Disease Cancer
Amantadine (1-Adamantanamine) sulfate is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine sulfate inhibits several ion channels such as NMDA and M2, and also inhibits Coronavirus ion channels. Amantadine sulfate also has anti-orthopoxvirus and anticancer activity. Amantadine sulfate can be used for Parkinson's disease, postoperative cognitive dysfunction (POCD) and COVID-19 research .

HY-Y0316S

*Sodium-dodecyl sulfate-d25* Sodium lauryl sulfate-d25; Laurylsulfuric acid-d25 sodium salt	Isotope-Labeled Compounds	Others
Sodium-dodecyl sulfate-d₂₅ is a deuterium labeled Sodium dodecyl sulfate. Sodium dodecyl sulfate is the most widely used of the anionic alkyl sulfate surfactants .

HY-W094477D

*Magnesium sulfate* heptahydrate, for molecular biology** Epsom salts, for molecular biology	Biochemical Assay Reagents	Others Cancer
Magnesium sulfate heptahydrate, for molecular biology is a biochemical assay reagent and is suitable fo molecular biology.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-17565

Bleomycin sulfate Maximum Cited Publications 191 Publications Verification Bleomycin sulfate	Microorganisms Classification of Application Fields Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Anticancer Disease Research Fields Other Antibiotics Source Classification Cancer	DNA/RNA Synthesis Antibiotic
Bleomycin sulfate is a DNA synthesis inhibitor. Bleomycin hydrochloride is a DNA damaging agent. Bleomycin sulfate is an antitumor antibiotic .

HY-B0470

Neomycin sulfate 65+ Cited Publications	Structural Classification Classification of Application Fields Antibacterial Disease Research Other Antibiotics Infection Microorganisms Antibiotics Animal Husbandry Mammalian Cell Culture Anticancer Disease Research Fields Source Classification	Environmental Pollutants Antibiotic Phospholipase Bacterial
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both the nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis. Neomycin sulfate inhibits IP3-mediated Ca ²⁺ release, MgATP-dependent Ca ²⁺ uptake, and electrical excitation-evoked skeletal muscle Ca ²⁺ transients. Neomycin sulfate depletes gut microbiota in specific mouse models, causes hearing impairment, and kidney damage with prolonged exposure. Neomycin sulfate can be used for the research of cancer .

HY-N0488

Vincristine sulfate 70+ Cited Publications Leurocristine sulfate; NSC-67574 sulfate; 22-Oxovincaleukoblastine sulfate	Apocynaceae Alkaloids Structural Classification Classification of Application Fields Anti-aging Plants Disease Research Fields Alkaloid Dimers Catharanthus roseus (L.) G. Don Source Classification Cancer	Apoptosis Microtubule/Tubulin Mitosis
Vincristine (Leurocristine; NSC-67574; 22-Oxovincaleukoblastine) sulfate is a microtubule inhibitor that disrupts microtubule polymerization by binding to β-tubulin (with a K_i of 85 nM in bovine), arrests the cell cycle and induces apoptosis. Vincristine sulfate inhibits cell replication, tumor blood flow and the proliferation of various cancer cells, while triggering effects such as oxidative stress, inflammation, calcium overload, epithelial-mesenchymal transition and peripheral neuropathic pain. Vincristine sulfate upregulates the expression of various transporters and nuclear receptors, and enriches gastric cancer stem-like cells. Vincristine sulfate is used in research related to various tumors including acute lymphoblastic leukemia, lymphoma, melanoma, gastric cancer, solid tumors and sarcomas .

HY-A0276

Gentamicin sulfate 60+ Cited Publications	Structural Classification Classification of Application Fields Antibacterial Disease Research Other Antibiotics Plant agriculture research Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Animal Husbandry Mammalian Cell Culture Disease Research Fields Source Classification	Environmental Pollutants Antibiotic Bacterial
Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. Gentamicin sulfate inhibits DNase I with an IC₅₀ of 0.57 mM .

HY-13780

Vinblastine sulfate 15+ Cited Publications Vincaleukoblastine sulfate salt	Apocynaceae Alkaloids Classification of Application Fields Plants Disease Research Fields Alkaloid Dimers Catharanthus roseus (L.) G. Don Source Classification Cancer	Microtubule/Tubulin nAChR Autophagy
Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC₅₀ of 8.9 μM.

HY-A0248

Polymyxin B Sulfate 20+ Cited Publications	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Polymyxin B Sulfate is an antibiotic. Polymyxin B Sulfate inhibits Gram-negative infections by binding to the LPS of the bacterial wall with high affinity. Polymyxin B Sulfate neutralizes the effect of endotoxin. Polymyxin B Sulfate induces bacterial death by increasing its permeability. Polymyxin B Sulfate is used in endotoxemia research .

HY-101916

Heparan Sulfate 15+ Cited Publications	Polysaccharides Neurological Disease Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides Source Classification	FGFR Wnt Endogenous Metabolite
Heparan sulfate, a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on the cell surface and in the extracellular matrix.

HY-16566A

Kanamycin sulfate 25+ Cited Publications Kanamycin A sulfate	Anti-inflammation/Immunoregulatory Classification of Application Fields Antibacterial Disease Research Other Antibiotics Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Fields Source Classification	Bacterial Antibiotic
Kanamycin (Kanamycin A) sulfate is an orally active antibacterial (gram-negative/positive bacteria) agent, inhibits translocation and causes misencoding by binding to the 70 S ribosomal subunit. Kanamycin sulfate shows good inhibitory activity to both M. tuberculosis (sensitive and drug-resistant ) and K. pneumonia, which can be used in studies of tuberculosis and pneumonia .

HY-B1329

Apramycin sulfate 4 Publications Verification Nebramycin II sulfate	Microorganisms Classification of Application Fields Antibiotics Animal Husbandry Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification Cancer	Bacterial Antibiotic
Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic .

HY-111431

p-Cresyl sulfate 5+ Cited Publications p-Tolyl sulfate	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	JNK p38 MAPK Reactive Oxygen Species (ROS)
p-Cresyl sulfate (p-Tolyl sulfate) is a uremic toxin, that can cause renal damage and dysfunction. p-Cresyl sulfate shows antiproliferation activity. p-Cresyl sulfate increases the protein expression of HIF-1α and VHL, decreases the protein expression of HIF-2α. p-Cresyl sulfate induces epithelial-mesenchymal transition (EMT). p-Cresyl sulfate activates the JNK and p38 MAPK signaling pathways .

HY-N0716B

Berberine sulfate 75+ Cited Publications Natural Yellow 18 sulfate	Alkaloids Classification of Application Fields Coptis chinensis Franch. Ranunculaceae Plants Isoquinoline Alkaloids Inflammation/Immunology Disease Research Fields Source Classification	Antibiotic Topoisomerase Autophagy Bacterial Reactive Oxygen Species (ROS) Parasite Apoptosis PI3K Akt Caspase JNK AP-1 NF-κB
Berberine sulfate is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine sulfate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Berberine sulfate has antineoplastic properties. The sulfate form improves bioavailability .

HY-113293B

*Estrone sulfate* sodium** 3 Publications Verification	Structural Classification Classification of Application Fields Endogenous metabolite Disease Research Fields Steroids Source Classification Cancer	Endogenous Metabolite Estrogen Receptor/ERR
Estrone sulfate sodium is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate sodium is also a substrate of the OATP1B3 transporter. Estrone sulfate sodium can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate sodium stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate sodium is applicable to breast cancer-related research .

HY-B0472

Streptomycin sulfate 45+ Cited Publications	Structural Classification Classification of Application Fields Antibacterial Disease Research Other Antibiotics Plant agriculture research Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Disease Research Fields Source Classification	Environmental Pollutants Antibiotic Bacterial
Streptomycin sulfate is an aminoglycoside antibiotic, that inhibits protein synthesis.

HY-113416

Dehydroepiandrosterone sulfate 5 Publications Verification DHEA sulfate; Prasterone sulfate	Human Gut Microbiota Metabolites Microorganisms Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	GABA Receptor Sigma Receptor iGluR PPAR NF-κB
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABA_A receptor and agonist activity of σ₁ receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABA_A receptor-mediated chloride influx, enhance NMDA receptor activity through σ₁ receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .

HY-111431A

*p-Cresyl sulfate* potassium** 5+ Cited Publications p-Tolyl sulfate potassium	Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Metabolic Disease Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite JNK p38 MAPK
p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity .

HY-B0956

Paromomycin sulfate 4 Publications Verification Aminosidine sulfate	Classification of Application Fields Anti-parasitic Antibacterial Disease Research Other Antibiotics Infection Plant Cell Culture Microorganisms Antibiotics Resistance Selection Mammalian Cell Culture Disease Research Fields Source Classification	Antibiotic Parasite Bacterial
Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections .

HY-B1222

Sisomicin sulfate 5 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria.

HY-111355B

*Cholesteryl sulfate* sodium**	Structural Classification Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Sirtuin Endogenous Metabolite PKC AMPK DOCK
Cholesterol sulfate sodium is a naturally occurring, orally active cholesterol derivative that is widely distributed in various tissues and body fluids. Cholesterol sulfate sodium acts as a DOCK2 inhibitor, with IC₅₀ values of 2 μM and 2.9 μM against mouse and human targets, respectively. Cholesterol sulfate sodium restricts excessive neutrophil infiltration and alleviates intestinal inflammation and damage. Cholesterol sulfate sodium serves as an activator of protein kinase C (PKC), which promotes squamous cell differentiation and inhibits skin carcinogenesis. Cholesterol sulfate sodium regulates cholesterol homeostasis and cellular metabolism by activating the AMPK-Sirt1 pathway. Cholesterol sulfate sodium can be used in research related to actinic keratitis, ulcerative colitis, skin cancer, and other conditions .

HY-17566

Capreomycin sulfate 5 Publications Verification	Infection Microorganisms Classification of Application Fields Antibiotics Mammalian Cell Culture Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. Capreomycin sulfate has anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting the occurrence of amyloid fibrillation. Capreomycin sulfate can be used in the study of multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease and Parkinson's disease .

HY-B0765

*Dehydroepiandrosterone sulfate* sodium** 5 Publications Verification DHEA sulfate sodium; Prasterone sulfate sodium	Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	GABA Receptor Sigma Receptor iGluR PPAR NF-κB
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABA_A receptor and agonist activity of σ₁ receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABA_A receptor-mediated chloride influx, enhance NMDA receptor activity through σ₁ receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .

HY-B1228

Ribostamycin sulfate 1 Publications Verification Vistamycin sulfate	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Resistance Selection Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Antibiotic PDI
Ribostamycin sulfate (Vistamycin sulfate) is a broad-spectrum aminoglycoside Antibiotic with bactericidal activity against Gram-positive cocci, Gram-negative cocci, bacilli, and drug-resistant strains. Ribostamycin sulfate also acts as an inhibitor of protein disulfide isomerase (PDI), with a binding constant K_D of 319 μM for bovine PDI. Ribostamycin sulfate targets bacterial 16S ribosomal RNA and the 30S ribosomal subunit, causing translational misreading and thereby inhibiting bacterial protein synthesis. Ribostamycin sulfate disrupts the integrity of bacterial cell membranes, induces membrane pore formation, and leads to bacterial death. Ribostamycin sulfate can be used in studies related to bacterial infections .

HY-129071

Vindesine sulfate	Apocynaceae Structural Classification Piperidine Alkaloids Pyrrole Alkaloids Plants Disease Research Fields Indole Alkaloids Catharanthus roseus (L.) G. Don Source Classification Cancer	Microtubule/Tubulin
Vindesine sulfate is a potent tubulin inhibitor with an K_i of 0.110 μM. Vindesine sulfate shows anti-proliferation effect in vitro. Vindesine sulfate shows antitumor effect in vivo .

HY-113074

Glycolithocholic acid 3-sulfate Glycolithocholate sulfate; Sulfolithocholylglycine; SLCG	Triterpenes Terpenoids Endogenous metabolite Source Classification	HIV Endogenous Metabolite
Glycolithocholic acid 3-sulfate (SLCG) is a cholic acid derivative and a metabolite of glycolithocholic acid. Glycolithocholic acid 3-sulfate inhibits replication of HIV-1 in vitro. Glycolithocholic acid 3-sulfate can be used for the research of HIV infection and gallbladder disease .

HY-113415A

*Testosterone sulfate* (pyridinium)** 1 Publications Verification	Structural Classification Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Steroids Source Classification	Endogenous Metabolite Drug Metabolite
Testosterone sulfate pyridinium is a Testosterone sulfate with a pyridinium. Testosterone sulfate pyridinium is the metabolite of Testosterone. Testosterone is the main male sex hormone which determination is useful for assessment of androgen status .

HY-113293A

*Estrone sulfate* potassium** 3 Publications Verification	Structural Classification Classification of Application Fields Endogenous metabolite Disease Research Fields Steroids Source Classification Cancer	Endogenous Metabolite Estrogen Receptor/ERR
Estrone sulfate potassium is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate potassium is also a substrate of the OATP1B3 transporter. Estrone sulfate potassium can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate potassium stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate potassium is applicable to breast cancer-related research .

HY-B0441A

Tobramycin sulfate 15+ Cited Publications Nebramycin Factor 6 sulfate; Deoxykanamycin B sulfate	Infection Structural Classification Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Bacterial Antibiotic
Tobramycin (Nebramycin Factor 6) sulfate is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms. Tobramycin sulfate can be used to pneumonia research caused by Pseudomonas aeruginosa .

HY-N0487

Glucosamine sulfate 10+ Cited Publications D-Glucosamine sulfate	Classification of Application Fields Endogenous metabolite Disease Research Fields Saccharides Source Classification Cancer	Endogenous Metabolite Reactive Oxygen Species (ROS) HIF/HIF Prolyl-Hydroxylase Autophagy
Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes .

HY-17367A

Atazanavir sulfate 10+ Cited Publications BMS-232632 sulfate	Infection Structural Classification Alkaloids Classification of Application Fields Pyridine Alkaloids Endogenous metabolite Disease Research Fields Source Classification Cancer	HIV HIV Protease SARS-CoV Cytochrome P450 P-glycoprotein Endogenous Metabolite Toll-like Receptor (TLR)
Atazanavir (BMS-232632) sulfate is a highly selective and orally active HIV-1 protease inhibitor with blood-brain barrier permeability. Atazanavir sulfate is a substrate and inhibitor of CYP3A4, and an inhibitor of P-glycoprotein (P-gp). Atazanavir sulfate is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 3.49 μM. Atazanavir sulfate inhibits cardiac fibrosis, hyperlipidemia and induces malignant glioma death .

HY-131150

Ristomycin sulfate	Structural Classification Microorganisms Classification of Application Fields Antibiotics Antibacterial Disease Research Inflammation/Immunology Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Ristomycin sulfate is an antibacterial antibiotic and platelet aggregation inducer. Ristomycin sulfate interacts with the D-alanyl-D-alanine terminus of bacterial cell wall precursors to regulate bacterial cell wall synthesis. Ristomycin sulfate induces platelet aggregation in vitro and inhibits the growth of Gram-positive bacteria. Ristomycin sulfate serves as an in vitro diagnostic compound for detecting von Willebrand factor activity. Ristomycin sulfate is applicable to research related to von Willebrand disease and Bernard-Soulier syndrome .

HY-111355

Cholesterol sulfate	Structural Classification Animals Steroids Source Classification	Endogenous Metabolite DOCK PKC AMPK Sirtuin
Cholesterol sulfate is a naturally occurring, orally active cholesterol derivative that is widely distributed in various tissues and body fluids. Cholesterol sulfate acts as a DOCK2 inhibitor, with IC₅₀ values of 2 μM and 2.9 μM against mouse and human targets, respectively. Cholesterol sulfate restricts excessive neutrophil infiltration and alleviates intestinal inflammation and damage. Cholesterol sulfate serves as an activator of protein kinase C (PKC), which promotes squamous cell differentiation and inhibits skin carcinogenesis. Cholesterol sulfate regulates cholesterol homeostasis and cellular metabolism by activating the AMPK-Sirt1 pathway. Cholesterol sulfate can be used in research related to actinic keratitis, ulcerative colitis, skin cancer, and other conditions .

HY-108307

Micronomicin sulfate 1 Publications Verification Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate	Infection Microorganisms Anti-inflammation/Immunoregulatory Antibiotics Antibacterial Disease Research Disease Research Fields Other Antibiotics Source Classification	Antibiotic Bacterial
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml) .

HY-A0089R

*Colistin sulfate* (Standard)** Polymyxin E sulfate (Standard)	Structural Classification Microorganisms Antibiotics Animal Husbandry Antibacterial Disease Research Other Antibiotics Source Classification	Reference Standards Bacterial Autophagy Antibiotic
Colistin (sulfate) (Standard) is the analytical standard of Colistin (sulfate). This product is intended for research and analytical applications. Colistin sulfate is a polypeptide antibiotic which inhibits gram-negative bacteria by binding to lipopolysaccharides and phospholipids in the outer cell membrane of gram-negative bacteria.

HY-101406

Thyroxine sulfate 4 Publications Verification T4 sulfate	Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Endocrinology Source Classification	Thyroid Hormone Receptor Drug Metabolite Endogenous Metabolite
Thyroxine sulfate is a thyroid hormone metabolite.

HY-N0430A

Coptisine Sulfate 5 Publications Verification	Alkaloids Structural Classification Chelidonium majus Classification of Application Fields Metabolic Disease Quinoline Alkaloids Plants Disease Research Fields Papaveraceae Source Classification	Indoleamine 2,3-Dioxygenase (IDO) NF-κB p38 MAPK PI3K Akt Apoptosis Reactive Oxygen Species (ROS) Mitochondrial Metabolism DNA/RNA Synthesis ROCK LDLR
Coptisine Sulfate is an orally active and brain-penetrant alkaloid found in Coptis chinensis. Coptisine Sulfate is a reversible, uncompetitive IDO inhibitor with a K_i of 5.8 μM and an IC₅₀ of 6.3 μM. Coptisine Sulfate suppresses neuroinflammation, reduces Aβ plaque burden and shows neuroprotective activity. Coptisine Sulfate shows anti-inflammation activity by blocking NF-κB, MAPK, and PI3K/Akt activation. Coptisine Sulfate inhibits cancer cells proliferation, induces DNA damage, G2/M phase cell cycle arrest, apoptosis, ROS production and mitochondrial dysfunction. Coptisine Sulfate inhibits Rho/ROCK pathway activation, reduces arrhythmia, limits cardiac injury marker release, reduces infarct size, and preserves cardiac function in rat myocardial ischemia/reperfusion models. Coptisine Sulfate downregulates HMGCR and upregulates LDLR and CYP7A1 to modulate cholesterol metabolism, reduces abnormal serum lipid levels, and promotes fecal bile acid excretion. Coptisine Sulfate be used for the research of cancer, hypercholesterolemia, Alzheimer’s disease, inflammatory disorders and cardiovascular disease .

HY-17657

*Androst-5-enediol sulfate* sodium** 5-Androstenediol 3-sulfate sodium	Structural Classification Endogenous metabolite Steroids Source Classification	Drug Intermediate
Androst-5-enediol sulfate (5-Androstenediol 3-sulfate) sodium salt is an adrenal Δ5-steroid sulfate that synthesized by zona reticularis of adrenal depending on the lyase and Cytochrome b5 type A (CYB5A) activity. Androst-5-enediol sulfate sodium salt is a precursor hormone and can be desulfated to produce more potent androgens, including testosterone, in peripheral tissues like skin and liver. The serum level of Androst-5-enediol sulfate sodium salt has an age-related increase .

HY-128442

Phenyl sulfate Phenyl hydrogen sulfate	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Phenyl sulfate is an orally active gut microbiota-derived metabolite. Phenyl sulfate induces albuminuria and podocyte damage in experimental models of diabetes. Phenyl sulfate can be used as a disease marker in diabetic kidney disease .

HY-W779068

*Chenodeoxycholic acid 3-sulfate* disodium**	Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Steroids Source Classification	Endogenous Metabolite
Chenodeoxycholic acid 3-sulfate disodium is a bile acid. Chenodeoxycholic acid 3-sulfate disodium level corresponds closely with the extent of hepatic dysfunction .

HY-45609

*L-Cysteine S-sulfate* sodium hydrate**	Structural Classification Natural Products Neurological Disease Classification of Application Fields Endogenous metabolite Disease Research Fields Source Classification	Drug Derivative
L-Cysteine S-sulfate sodium hydrate is an S-sulfated derivative of L-cysteine (HY-Y0337). L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry and chromatography analyses .

HY-13780R

*Vinblastine sulfate* (Standard)** Vincaleukoblastine sulfate salt (Standard)	Apocynaceae Alkaloids Structural Classification Plants Alkaloid Dimers Catharanthus roseus (L.) G. Don Source Classification	Reference Standards Microtubule/Tubulin Autophagy nAChR
Vinblastine (sulfate) (Standard) is the analytical standard of Vinblastine (sulfate). This product is intended for research and analytical applications. Vinblastine sulfate is a cytotoxic alkaloid used against various cancer types. Vinblastine sulfate inhibits the formation of microtubule and suppresses nAChR with an IC₅₀ of 8.9 μM.

HY-113415

Testosterone sulfate	Structural Classification Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite Drug Metabolite
Testosterone sulfate is a Testosterone sulfate with a pyridinium. Testosterone sulfate is the metabolite of Testosterone. Testosterone is the main male sex hormone which determination is useful for assessment of androgen status .

HY-W740171

*Ethynylestradiol 3-sulfate* sodium**	Other Terpenoids Terpenoids Endogenous metabolite Source Classification	Biochemical Assay Reagents
Ethynyl Estradiol 3-Sulfate Sodium Salt is a biological molecule.

HY-111769

Taurochenodeoxycholate-3-sulfate	Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Steroids Source Classification	Endogenous Metabolite
Taurochenodeoxycholate-3-sulfate is a bile salt found in urine .

HY-150526

EGCG-4″-sulfate	Flavonoids Classification of Application Fields Flavanols Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification Cancer	Endogenous Metabolite Apoptosis
EGCG-4″-sulfate is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis. (-)-Epigallocatechin Gallate sulfate inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. EGCG-4″-sulfate has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma .

HY-N8460A

*Cortisol sulfate* sodium** 1 Publications Verification Cortisol 21-sulfate sodium	Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Steroids Source Classification	Endogenous Metabolite
Cortisol sulfate sodium (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate sodium is a specific ligand for intracellular transcortin .

HY-N0471A

L-Hyoscyamine sulfate 2 Publications Verification Daturine sulfate	Alkaloids other families Other Alkaloids Plants Source Classification	mAChR
L-Hyoscyamine sulfate (Daturine sulfate), a natural plant tropane alkaloid, is a potent and competitive muscarinic receptor (MR) antagonist. L-Hyoscyamine sulfate is a levo-isomer to Atropine (HY-B1205) .

HY-B1222R

*Sisomicin sulfate* (Standard)**	Structural Classification Microorganisms Antibiotics Antibacterial Disease Research Other Antibiotics Source Classification	Reference Standards Bacterial Antibiotic
Sisomicin (sulfate) (Standard) is the analytical standard of Sisomicin (sulfate). This product is intended for research and analytical applications. Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria [4].

HY-N6901

Luteolin 7-sulfate	Flavonoids other families Classification of Application Fields Flavones Phenols Polyphenols Metabolic Disease Plants Disease Research Fields Source Classification	Epigenetic Reader Domain
Luteolin 7-sulfate is isolated from Phyllospadix iwatensis Makino, a marine plant. Luteolin 7-sulfate attenuates TYR gene expression through the intervention of a cAMP-responsive element binding protein (CREB)- and microphthalmia-associated transcription factor (MITF)-mediated signaling pathway, leading to the decreased melanin synthesis .

HY-B0470R

*Neomycin sulfate* (Standard)**	Structural Classification Microorganisms Antibiotics Animal Husbandry Mammalian Cell Culture Antibacterial Disease Research Anticancer Other Antibiotics Source Classification	Reference Standards Bacterial Antibiotic Phospholipase
Neomycin (sulfate) (Standard) is the analytical standard of Neomycin (sulfate). This product is intended for research and analytical applications. Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis .

HY-113084

L-Cysteine S-sulfate	Structural Classification Natural Products Immune System Disorder Neurological Disease Classification of Application Fields Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields	Drug Derivative
L-Cysteine S-sulfate is an S-sulfated derivative of L-cysteine (HY-Y0337). L-Cysteine S-sulfate is the substrate for cystine lyase, it can be used in mass spectrometry and chromatography analyses .

HY-N8460

Cortisol sulfate Cortisol 21-sulfate	Classification of Application Fields Endogenous metabolite Disease Research Fields Endocrinology Steroids Source Classification	Endogenous Metabolite
Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate is a specific ligand for intracellular transcortin .

Cat. No.	Product Name	Chemical Structure

HY-113293BS1

Estrone sulfate-d4 sodium

Estrone sulfate-d₄ sodium is the deuterium labeled Estrone sulfate sodium (HY-113293B). Estrone sulfate sodium is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate sodium is also a substrate of the OATP1B3 transporter. Estrone sulfate sodium can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate sodium stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate sodium is applicable to breast cancer-related research .

HY-132429S

Potassium 1H-indol-3-yl sulfate-d5

Potassium 1H-indol-3-yl sulfate-d₅ is the deuterium labeled 3-Indoxyl Sulfate potassium. Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases.

HY-111431AS

*p-Cresol sulfate-d7 potassium*
p-Cresol sulfate-d₇ (potassium) is the deuterium labeled p-Cresyl sulfate potassium. p-Methylphenyl potassium sulfate is a prototype protein-bound uremic toxin[1][2].

HY-141921S

Dehydroepiandrosterone sulfate sodium-d6

Dehydroepiandrosterone sulfate sodium salt-d₆ (DHEA sulfate sodium salt-d₆; Prasterone sulfate sodium salt-d₆) is the deuterium labeled Dehydroepiandrosterone sulfate sodium salt (HY-B0765). Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium salt has both non-competitive antagonist activity of GABA_A receptor and agonist activity of σ₁ receptor. Dehydroepiandrosterone sulfate sodium salt can partially penetrate the blood-brain barrier, inhibit GABA_A receptor-mediated chloride influx, enhance NMDA receptor activity through σ₁ receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium salt participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium salt may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .

HY-113296S

*Indoxyl sulfate-13C6 potassium*
Indoxyl Sulfate Potassium Salt- ¹³C₆ is the ¹³C labeled Indoxyl Sulfate Potassium Salt .

HY-143831S

Cefepime-d8 sulfate

Cefepime-d₈ (BMY-28142-d₈) sulfate is deuterium labeled Cefepime sulfate. Cefepime sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC₅₀ of 21.115 mM and a K_i of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABA_A receptors. Cefepime sulfate penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase.

HY-W011910S

Potassium 1H-indol-3-yl sulfate-d4

Potassium 1H-indol-3-yl sulfate-d₄ potassium is the deuterium labeled Potassium 1H-indol-3-yl sulfate. Potassium 1H-indol-3-yl sulfate is a metabolite of tryptophan, produced by intestinal microorganisms and combined with sulfate in the liver before entering the circulatory system. Potassium 1H-indol-3-yl sulfate is a potent endogenous agonist of the aryl hydrocarbon receptor (AhR) and a urinary toxin. Potassium 1H-indol-3-yl sulfate can be used for research on kidney diseases.

HY-B0394S

Atropine-d5
Atropine-d₅ is the deuterium labeled Atropine (sulfate monohydrate). Atropine (Tropine tropate) sulfate monohydrate is a broad-spectrum and competitive muscarinic acetylcholine receptor (mAChR) antagonist with anti-myopia effect .

HY-141672S1

*17β-Estradiol sulfate-d4 sodium*
17β-Estradiol sulfate-d₄ (sodium) is the deuterium labeled 17β-Estradiol sulfate 17β-Estradiol sulfate (sodium), also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .

HY-113441S

*3-Methoxy-4-Hydroxyphenylglycol sulfate-d3 potassium*
3-Methoxy-4-Hydroxyphenylglycol sulfate-d₃ potassium is the deuterium labeled 3-Methoxy-4-Hydroxyphenylglycol sulfate potassium .

HY-W654100

Cefepime-d3 sulfate

Cefepime-d₃ (BMY-28142-d₃) sulfate is deuterium labeled Cefepime sulfate. Cefepime sulfate is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC₅₀ of 21.115 mM and a K_i of 35.092 mM. Cefepime sulfate inhibits hPON1 via a non-competitive mechanism and blocks GABA_A receptors. Cefepime sulfate penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase.

HY-104026S5

*L-Kynurenine-13C10 sulfate* hydrate**
L-Kynurenine-13C10 sulfate hydrate is the C13 labeled L-Kynurenine sulfate hydrate. L-Kynurenine is an aryl hydrocarbon receptor agonist .

HY-Y0316S

*Sodium-dodecyl sulfate-d25*
Sodium-dodecyl sulfate-d₂₅ is a deuterium labeled Sodium dodecyl sulfate. Sodium dodecyl sulfate is the most widely used of the anionic alkyl sulfate surfactants .

HY-113416AS

Dehydroepiandrosterone sulfate-d6 sodium dihydrate

Dehydroepiandrosterone sulfate sodium dihydrate-d₆ sodium dihydrate is the deuterium labeled Dehydroepiandrosterone sulfate sodium dihydrate. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium dihydrate is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate sodium dihydrate has both non-competitive antagonist activity of GABA_A receptor and agonist activity of σ₁ receptor. Dehydroepiandrosterone sulfate sodium dihydrate can partially penetrate the blood-brain barrier, inhibit GABA_A receptor-mediated chloride influx, enhance NMDA receptor activity through σ₁ receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate sodium dihydrate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate sodium dihydrate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality .

HY-111355S

Cholesterol sulfate-d7 sodium

Cholesterol sulfate sodium-d₇ is the deuterium labeled Cholesterol sulfate sodium. Cholesterol sulfate sodium is a naturally occurring, orally active cholesterol derivative that is widely distributed in various tissues and body fluids. Cholesterol sulfate sodium acts as a DOCK2 inhibitor, with IC₅₀ values of 2 μM and 2.9 μM against mouse and human targets, respectively. Cholesterol sulfate sodium restricts excessive neutrophil infiltration and alleviates intestinal inflammation and damage. Cholesterol sulfate sodium serves as an activator of protein kinase C (PKC), which promotes squamous cell differentiation and inhibits skin carcinogenesis. Cholesterol sulfate sodium regulates cholesterol homeostasis and cellular metabolism by activating the AMPK-Sirt1 pathway. Cholesterol sulfate sodium can be used in research related to actinic keratitis, ulcerative colitis, skin cancer, and other conditions.

HY-N0488S

Vincristine-d3 sulfate

Vincristine-d₃ sulfate is the deuterium labeled Vincristine sulfate. Vincristine sulfate (Leurocristine; NSC-67574; 22-Oxovincaleukoblastine) is a microtubule inhibitor that disrupts microtubule polymerization by binding to β-tubulin (with a K_i of 85 nM in bovine), arrests the cell cycle and induces apoptosis. Vincristine sulfate inhibits cell replication, tumor blood flow and the proliferation of various cancer cells, while triggering effects such as oxidative stress, inflammation, calcium overload, epithelial-mesenchymal transition and peripheral neuropathic pain. Vincristine sulfate upregulates the expression of various transporters and nuclear receptors, and enriches gastric cancer stem-like cells. Vincristine sulfate is used in research related to various tumors including acute lymphoblastic leukemia, lymphoma, melanoma, gastric cancer, solid tumors and sarcomas .

HY-B1370S

Hydroxychloroquine-d4 sulfate
Hydroxychloroquine-d₄ (sulfate) is the deuterium labeled Hydroxychloroquine sulfate. Hydroxychloroquine sulfate (HCQ sulfate) is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine sulfate is efficiently inhibits SARS-CoV-2 infection in vitro .

HY-144152S

*Catechol sulfate-d4 sodium*
Catechol sulfate-d₄ (sodium) is the deuterium labeled Catechol sulfate sodium .

HY-132641S

*Equilin 3-Sulfate-d4 sodium salt*
Equilin 3-Sulfate-d₄ (sodium) is the deuterium labeled Equilin 3-Sulfate sodium salt .

HY-141918S

*Chenodeoxycholic acid 3-sulfate-d4 disodium*
Chenodeoxycholic acid 3-sulfate-d₄ disodium is the deuterium labeled Chenodeoxycholic acid 3-sulfate .

HY-143645S

*Glycochenodeoxycholic acid 3-sulfate-d5 disodium*
Glycochenodeoxycholic acid 3-sulfate-d₅ (disodium) is the deuterium labeled Glycochenodeoxycholic acid 3-sulfate disodium .

HY-150779S

Choline-d13 sulfate
Choline-d₁₃ (sulfate) is the deuterium labeled Choline sulfate .

HY-B1018AS

Phenelzine-d5 sulfate

Phenelzine-d5 sulfate is the deuterium labeled Phenelzine sulfate (HY-B1018A). Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (Ki: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .

HY-101238S

Agmatine-d8 sulfate
Agmatine-d₈ sulfate is a deuterium labeled Agmatine sulfate (HY-101238). Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor .

HY-146712S

*N-(4-Hydroxyphenyl)acetamide sulfate-d3 sodium*
N-(4-Hydroxyphenyl)acetamide sulfate-d₃ (sodium) is the deuterium labeled N-(4-Hydroxyphenyl)acetamide sulfate.

HY-W031727S

Hydroxychloroquine-d4-1 sulfate
Hydroxychloroquine-d₄-1 (sulfate) is the deuterium labeled Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro .

HY-113238S1

*Lithocholic acid 3-sulfate-d4（ sodium salt）*
Lithocholic acid 3-sulfate-d₄（sodium salt） is the deuterium labeled Lithocholic acid 3-sulfate .

HY-66006AS

*4-Acetaminophen sulfate-d3 potassium*
4-Acetaminophen sulfate-d₃ (potassium) is the deuterium labeled 4-Acetaminophen sulfate potassium .

HY-113293BS

Estrone sulfate-d5 sodium

Estrone sulfate-d₅ sodium is the deuterium labeled Estrone sulfate sodium (HY-113293B). Estrone sulfate sodium is an inactive endogenous estrogen that can be converted into Estrone (HY-B0234) and Estradiol (HY-B0141). Estrone sulfate sodium is also a substrate of the OATP1B3 transporter. Estrone sulfate sodium can be converted into Estrone and Estradiol in normal mammary parenchymal cells. Estrone sulfate sodium stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion into Estrone and Estradiol occurring both in vivo and in vitro during this process. Estrone sulfate sodium is applicable to breast cancer-related research .

HY-N0488S2

Vincristine-d6 sulfate

Vincristine-d₆ (sulfate) is the deuterium labeled Vincristine sulfate. Vincristine sulfate (Leurocristine; NSC-67574; 22-Oxovincaleukoblastine) is a microtubule inhibitor that disrupts microtubule polymerization by binding to β-tubulin (with a K_i of 85 nM in bovine), arrests the cell cycle and induces apoptosis. Vincristine sulfate inhibits cell replication, tumor blood flow and the proliferation of various cancer cells, while triggering effects such as oxidative stress, inflammation, calcium overload, epithelial-mesenchymal transition and peripheral neuropathic pain. Vincristine sulfate upregulates the expression of various transporters and nuclear receptors, and enriches gastric cancer stem-like cells. Vincristine sulfate is used in research related to various tumors including acute lymphoblastic leukemia, lymphoma, melanoma, gastric cancer, solid tumors and sarcomas .

HY-W010973S

*5-Hydroxytryptamine-d4 creatinine sulfate* monohydrate**
5-Hydroxytryptamine-d₄ creatinine sulfate monohydrate is the deuterium labeled 5-Hydroxytryptamine creatinine sulfate monohydrate. 5-Hydroxytryptamine creatinine sulfate monohydrate is an endogenous metabolite.

HY-N0488S1

Vincristine-d3-1 sulfate

Vincristine-d₃ sulfate is the deuterium labeled Vincristine sulfate. Vincristine-1 sulfate (Leurocristine; NSC-67574; 22-Oxovincaleukoblastine) is a microtubule inhibitor that disrupts microtubule polymerization by binding to β-tubulin (with a K_i of 85 nM in bovine), arrests the cell cycle and induces apoptosis. Vincristine-1 sulfate inhibits cell replication, tumor blood flow and the proliferation of various cancer cells, while triggering effects such as oxidative stress, inflammation, calcium overload, epithelial-mesenchymal transition and peripheral neuropathic pain. Vincristine-1 sulfate upregulates the expression of various transporters and nuclear receptors, and enriches gastric cancer stem-like cells. Vincristine-1 sulfate is used in research related to various tumors including acute lymphoblastic leukemia, lymphoma, melanoma, gastric cancer, solid tumors and sarcomas .

HY-203708S1

*1,25-Dihydroxyvitamin D3 sulfate-d6 sodium*
1,25-Dihydroxyvitamin D3 sulfate-d₆ sodium is the deuterium labeled 1,25-Dihydroxyvitamin D3 sulfate sodium.

HY-104026CS

*L-Kynurenine-13C10 sulfate* hemihydrate**
L-Kynurenine- ¹³C10 (sulfate hemihydrate) is the ¹³C labeled L-Kynurenine sulfate. L-Kynurenine sulfate hemihydrate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

HY-104026BS

L-Kynurenine-13C10 sulfate
L-Kynurenine-13C10 (sulfate) is the 13C labeled L-Kynurenine sulfate. L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist that activates AHR-directed, naive T cell polarization to the anti-inflammatory Treg phenotype .

HY-137255S

*Taurolithocholic acid-3-Sulfate-d4 disodium*
Taurolithocholic Acid-3-Sulfate-d₄ （disodium salt） is the deuterium labeled Taurolithocholic Acid-3-Sulfate .

HY-W754114

*Nalmefene Sulfate-d3*
Nalmefene Sulfate-d₃ is the deuterium labeled Nalmefene (HY-107744). Nalmefene is a BBB-penetrable opioid receptor modulator. Nalmefene is an antagonist of MOR and DOR, and a partial agonist of KOR. Nalmefene has anti-inflammatory and neuroprotective activities. Nalmefene can be used in the research of reducing alcohol-dependent disorders .

HY-17412S1

Minocycline-d6 sulfate

Minocycline-d₆ sulfate is deuterated labeled Minocycline (HY-17412A). Minocycline is an orally active, potent and BBB-penetrated semi-synthetic tetracycline antibiotic. Minocycline is a hypoxia-inducible factor (HIF)-1α inhibitor. Minocycline shows anti-cancer, anti-inflammatory, and glutamate antagonist effects. Minocycline reduces glutamate neurotransmission and shows neuroprotective properties and antidepressant effects. Minocycline inhibits bacterial protein synthesis through binding with the 30S subunit of the bacterial ribosome, resulting in a bacteriostatic effect .

HY-W654121

*p-Cresol sulfate-d4 potassium*
p-Cresol sulfate-d₄ (potassium) is deuterium labeled p-Cresyl sulfate (potassium). p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity .

HY-B1134AS

Imazalil-d5 sulfate
Imazalil-d₅ (sulfate) is the deuterium labeled Imazalil sulfate .

HY-15283AS

(±)-Clopidogrel-d7 sulfate
(±)-Clopidogrel-d₇ (sulfate) is the deuterium labeled (±)-Clopidogrel sulfate .

HY-W743264

*17β-Estradiol sulfate-d3 sodium*
17β-Estradiol sulfate-d₃ sodium (17β-Estradiol 3-sulfate-d₃ sodium) is the deuterium labeled 17β-Estradiol sulfate sodium (HY-141672). 17β-Estradiol sulfate sodium, also known as β-Estradiol 3-sulfate sodium salt, is a neuroactive steroid .

HY-141944S

*Cortisol sulfate-d4 sodium*
Cortisol-21-sulfate-d₄ (sodium) is the deuterium labeled Cortisol-21-sulfate .

HY-154775S

*Ethinylestradiol sulfate-d4*
Ethinylestradiol sulfate-d₄ is deuterated labeled Ethinylestradiol sulfate.

HY-142768S

*Homovanillic acid sulfate-d3 sodium*
Homovanillic acid sulfate-d₃ (sodium) is the deuterium labeled Homovanillic acid sulfate sodium .

HY-141931S

*Glycolithocholic acid 3-sulfate-d4 sodium*
Glycolithocholic acid 3-sulfate-d₄ (sodium) is the deuterium labeled Glycolithocholic acid 3-sulfate .

HY-W096997S

Sodium octyl sulfate (SOS)-d17

Sodium octyl sulfate (SOS)-d₁₇ (Sodium capryl sulfate-d₁₇) is the deuterated analogue of Sodium octyl sulfate (SOS). Sodium octyl sulfate (Sodium capryl sulfate; SOS) is a medium‑chain anionic surfactant. Sodium octyl sulfate (SOS) can undergo strong hydrophobic interactions with serum albumins (such as human serum albumin (HSA) and bovine serum albumin (BSA)), while exhibiting weak interactions with other proteins including myoglobin and hemoglobin. As an environmental pollutant in freshwater ecosystems, Sodium octyl sulfate (SOS) can mimic interspecific pheromones released by Daphnia magna and induce the formation of multicellular colonies in green algae.

HY-141916S

*Glycodeoxycholic acid sulfate-d4 disodium*
Taurodeoxycholic Acid-3-Sulfate-d₄ (Sodium) is the deuterium labeled Taurodeoxycholic Acid-3-Sulfate .

HY-111660S

*3-Methoxytyramine sulfate-d4*
3-Methoxytyramine sulfate-d₄ is deuterium labeled 3-Methoxytyramine sulfate.

HY-66006S1

*4-Acetaminophen sulfate-d4*
4-Acetaminophen sulfate-d₄ is deuterated labeled 4-Acetaminophen sulfate.

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