Integrin
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Integrin Inhibitors
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Integrin Agonists
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Integrin Antagonists
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Integrin Substrate
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Integrin Ligands
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Integrin Related Products (380)
Related Products (380)
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IMGN388 Antibody
0 ImagesCat. No.: HY-P991644Purity: 99.0%IMGN388 Antibody is an Integrin targeting humanized monoclonal antibody. IMGN388 Antibody can be used for synthesis ADCs.
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STX-100 (Biotinylated)
0 ImagesCat. No.: HY-P990667BSynonyms: BG00011 (Biotinylated)STX-100 (BG00011) Biotinylated is a biotin-labeled STX-100 (HY-P990667). STX-100 is a humanized antibody expressed in HEK293 cells, targeting Integrin aVb6 (ITGAV & ITGB6).
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c(phg-isoDGR-(NMe)k) TFA
0 ImagesCat. No.: HY-111413APurity: 99.63%c(phg-isoDGR-(NMe)k) TFA is a selective and potent α5β1-integrin ligand with an IC50 of 2.9 nM.
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EILEVPST
0 ImagesEILEVPST is a recombinant human fibronectinderived low-molecular-weight peptide fragment. EILEVPST can promote cell type-specific α4 integrin-mediated adhesion. EILEVPST can be used for the research of thrombogenesis.
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C16Y acetate
0 ImagesCat. No.: HY-P10704APurity: 98.60%C16Y acetate is a short peptide and an inhibitor of integrins αvβ3 and α5β1. C16Y acetate acts on the cell membrane and exerts its anticancer activity by inhibiting angiogenesis .
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REDV TFA
0 ImagesCat. No.: HY-P3522APurity: 99.81%REDV TFA is the minimal active sequence within the CS5 site of the alternatively spliced type III connecting segment (IIICS) region of fibronectin. REDV TFA can mediate adhesion to the IIICS region of plasma fibronectin by binding the integrin alpha 4 beta 1(α4β1). REDV TFA can be used for the research of cell adhesion.
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12(S)-HETrE
0 Images12(S)-HETrE is a fatty acid metabolite that inhibits platelet aggregation. 12(S)-HETrE can be used in thrombosis-related research.
The product specifications provided below refer solely to the active content of 12(S)-HETrE.
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Anti-Mouse CD18 Antibody (M18/2)
0 ImagesCat. No.: HY-P990288Anti-Mouse CD18 Antibody (M18/2) is a rat-derived IgG2a κ type antibody inhibitor, targeting to mouse CD18. Anti-Mouse CD18 Antibody (M18/2) can neutralize lymphocyte function-associated antigen 1 (LFA-1). Anti-Mouse CD18 Antibody (M18/2) can be used for the researches of immunology, such as heart transplantation.
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Anti-vWF Antibody
0 ImagesCat. No.: HY-P990544Synonyms: AJW 200; AJvW 2Anti-vWF Antibody is a humanized antibody expressed in CHO cells that targets vWF. The Anti-vWF Antibody is equipped with huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 145.62 kDa. The isotype control for Anti-vWF Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Anti-Mouse/Human Integrin β7 Antibody (FIB504)
0 ImagesCat. No.: HY-P990207Purity: 99.70%Anti-Mouse/Human Integrin β7 Antibody (FIB504) is an anti-mouse/human Integrin β7 IgG2a monoclonal antibody. Anti-Mouse/Human Integrin β7 Antibody (FIB504) can reduce the residence of type 2 innate lymphoid cells (ILC2s). Anti-Mouse/Human Integrin β7 Antibody (FIB504) can be used for researches on inflammation conditions and cancer such as lupus nephritis and glioma.
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Lefradafiban
0 ImagesSynonyms: BIBU-104Lefradafiban (BIBU-104) is an orally effective glycoprotein IIb/IIIa receptor blocker. The active metabolite of Lefradafiban, Fradafiban (HY-101720), blocks the platelet glycoprotein IIb/IIIa receptor and inhibits fibrinogen-mediated platelet aggregation. Lefradafiban can be used in research on stable coronary artery disease, unstable angina, or myocardial infarction.
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Cilengitide (Standard)
0 ImagesSynonyms: EMD 121974 (Standard)Cilengitide (Standard) (EMD 121974 (Standard)) is the analytical standard of Cilengitide (HY-16141). This product is intended for research and analytical applications. Cilengitide (EMD 121974) is an integrin (integrin) inhibitor with blood-brain barrier permeability, with IC50 values against human targets as follows: 0.61 nM for αvβ3, 8.4 nM for αvβ5, 14.9 nM for α5β1, 5400 nM for αIIbβ3, 2050 nM for αvβ6, 2350 nM for αvβ8. Cilengitide inhibits the binding of integrins to vitronectin, fibronectin, fibrinogen and LAP (TGF-β), and serves as an internal standard for solid-phase integrin binding assays. Cilengitide inhibits tumor cell viability, induces apoptosis, reduces the phosphorylation levels of STAT3, AKT and mTOR, downregulates the expression of PD-L1, inhibits cell viability and angiogenesis, regulates anti-tumor immune responses and slows tumor growth. Cilengitide can be used in research related to glioblastoma, melanoma, advanced solid tumors and refractory brain tumors.
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Alicaforsen sodium
0 ImagesCat. No.: HY-145728ACAS No.: 331257-52-4Synonyms: ISIS-2302 sodiumAlicaforsen (ISIS-2302) sodium is an oligonucleotide and immunostimulant targeting human ICAM-1 mRNA. Alicaforsen sodium hybridizes to specific sites to reduce the expression level of ICAM-1. Alicaforsen sodium is applicable to relevant research on psoriasis, rheumatoid arthritis and inflammatory bowel disease.
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Tirofiban hydrochloride
0 ImagesCat. No.: HY-17369ACAS No.: 142373-60-2Synonyms: L700462 hydrochloride; MK383 hydrochlorideTirofiban (L700462) hydrochloride is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.
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Tirofiban hydrochloride solution
0 ImagesCat. No.: HY-FL17369CAS No.: 150915-40-5Synonyms: L700462 hydrochloride monohydrate solution; MK383 hydrochloride monohydrate solutionTirofiban hydrochloride solution is mainly composed of Tirofiban hydrochloride monohydrate (HY-17369). Tirofiban (L700462) hydrochloride monohydrate is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban hydrochloride monohydrate induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban hydrochloride monohydrate can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area.
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Alicaforsen sodium scrambled negative control
0 ImagesCat. No.: HY-145728DAlicaforsen sodium scrambled negative control is the sequence scrambled negative control of Alicaforsen sodium.
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Zalunfiban acetate
0 ImagesCat. No.: HY-119350CCAS No.: 2376629-15-9Synonyms: RUC-4 acetateZalunfiban (RUC-4) acetate is a potent, selective platelet αIIbβ3antagonist (IC50=45 nM). Zalunfiban acetate can be used for the research of myocardial infarction (MI).
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Ro 43-5054
0 ImagesCat. No.: HY-125668CAS No.: 138107-58-1Ro 43-5054 is a platelet glycoprotein IIb-IIIa receptor antagonist. Ro 43-5054 can be used in the research of early reocclusion after thrombolytic therapy.
