J208
J208 is a dual inhibitor for histone deacetylase (HDAC) and DNA methyltransferase (DNMT). J208 inhibits proliferation of cancer cells, as well as the migration/invasion of triple-negative breast cancer (TNBC) cells. J208 induces apoptosis, arrests the cell cycle at G0/G1 phase. J2008 activates the innate immune signalling pathway in TNBC, by inducing the expression of endogenous retroviruses (ERVs).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2116468-11-0
- Formel: C20H24N6O4
- Molecular Weight:412.44
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Alle DNA Methyltransferase Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
HDAC1 |
Chemical Information
-
CAS. Nr. 2116468-11-0
-
Molecular Weight 412.44
-
Formel C20H24N6O4
-
SMILES
O=C1C=CN(C(N1)=O)CC2=CC=C(C=C2)C3=CN(N=N3)CCCCCCC(NO)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)