NFE2L2 - NFE2 like bZIP transcription factor 2 Gene

Also Known as NRF2; HEBP1; Nrf-2; IMDDHH

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4780

About NFE2L2

Cytogenetic location: 2q31.2 Genomic coordinates (GRCh38): 2:177,230,303-177,264,727 (from NCBI)

This gene has 65 transcripts (splice variants), 218 orthologues, 3 paralogues and is associated with 97 phenotypes. Ubiquitous expression in esophagus (RPKM 93.8), thyroid (RPKM 52.1) and 24 other tissues.

Summary

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]

NFE2L2 Products (8)

mRNA Protein Name
NM_001145412.3 NP_001138884.1 nuclear factor erythroid 2-related factor 2 isoform 2
NM_006164.5 NP_006155.2 nuclear factor erythroid 2-related factor 2 isoform 1
NM_001313900.1 NP_001300829.1 nuclear factor erythroid 2-related factor 2 isoform 2
NM_001313904.1 NP_001300833.1 nuclear factor erythroid 2-related factor 2 isoform 6
NM_001313903.2 NP_001300832.1 nuclear factor erythroid 2-related factor 2 isoform 5
NM_001145413.3 NP_001138885.1 nuclear factor erythroid 2-related factor 2 isoform 3
NM_001313901.1 NP_001300830.1 nuclear factor erythroid 2-related factor 2 isoform 2
NM_001313902.2 NP_001300831.1 nuclear factor erythroid 2-related factor 2 isoform 4

NFE2L2 Protein Structure

bZIP_Maf

bZIP_Maf: bZIP Maf transcription factor (469 - 558)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 605 a.a.
Protein Preferred Names Protein Names

nuclear factor erythroid 2-related factor 2

  • nuclear factor erythroid-derived 2-like 2

  • nuclear factor, erythroid 2 like 2

NFE2L2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
NFE2L2 Q16236 APEX1 Homo sapiens P27695 32911434
Intra
NFE2L2 Q16236 APEX1 Homo sapiens P27695 32911434
Intra
NFE2L2 Q16236 IRF1 Homo sapiens P10914 32911434
Intra
NFE2L2 Q16236 IRF1 Homo sapiens P10914 32911434
Intra
NFE2L2 Q16236 CERS2 Homo sapiens Q96G23 32911434
Intra
NFE2L2 Q16236 CERS2 Homo sapiens Q96G23 32911434
Intra
NFE2L2 Q16236 ELF3 Homo sapiens P78545 32911434
Intra
NFE2L2 Q16236 ELF3 Homo sapiens P78545
FCS
32911434
Intra
NFE2L2 Q16236 ELF3 Homo sapiens P78545 32911434
Intra
NFE2L2 Q16236 ETV6 Homo sapiens P41212 32911434
Intra
NFE2L2 Q16236 ETV6 Homo sapiens P41212 32911434
Intra
NFE2L2 Q16236 ETV6 Homo sapiens P41212 32911434
Intra
NFE2L2 Q16236 ETV6 Homo sapiens P41212
FCS
32911434
Intra
NFE2L2 Q16236 ETS2 Homo sapiens P15036 32911434
Intra
NFE2L2 Q16236 ETS2 Homo sapiens P15036 32911434
Intra
NFE2L2 Q16236 BRPF3 Homo sapiens Q9ULD4 32911434
Intra
NFE2L2 Q16236 BRPF3 Homo sapiens Q9ULD4 32911434
Intra
NFE2L2 Q16236 CFAP299 Homo sapiens Q6V702 32911434
Intra
NFE2L2 Q16236 CFAP299 Homo sapiens Q6V702 32911434
Intra
NFE2L2 Q16236 MAFK Homo sapiens O60675
Y2H
21988832
Intra
NFE2L2 Q16236 MAFK Homo sapiens O60675 32911434
Intra
NFE2L2 Q16236 TEF Homo sapiens Q10587
FCS
32911434
Intra
NFE2L2 Q16236 TEF Homo sapiens Q10587 32911434
Intra
NFE2L2 Q16236 TEF Homo sapiens Q10587 32911434
Intra
NFE2L2 Q16236 TEF Homo sapiens Q10587 32911434
Intra
NFE2L2 Q16236 FOSB Homo sapiens P53539
FCS
32911434
Intra
NFE2L2 Q16236 FOSB Homo sapiens P53539 32911434
Intra
NFE2L2 Q16236 FOSB Homo sapiens P53539 32911434
Intra
NFE2L2 Q16236 FOSB Homo sapiens P53539 32911434
Intra
NFE2L2 Q16236 SP140 Homo sapiens Q13342
FCS
32911434
Intra
NFE2L2 Q16236 SP140 Homo sapiens Q13342 32911434
Intra
NFE2L2 Q16236 SP140 Homo sapiens Q13342 32911434
Intra
NFE2L2 Q16236 CREBL2 Homo sapiens O60519
FCS
32911434
Intra
NFE2L2 Q16236 CREBL2 Homo sapiens O60519 32911434
Intra
NFE2L2 Q16236 CREBL2 Homo sapiens O60519 32911434
Intra
NFE2L2 Q16236 CREBL2 Homo sapiens O60519 32911434
Intra
NFE2L2 Q16236 REL Homo sapiens Q04864 32911434
Intra
NFE2L2 Q16236 REL Homo sapiens Q04864
FCS
32911434
Intra
NFE2L2 Q16236 REL Homo sapiens Q04864 32911434
Intra
NFE2L2 Q16236 REL Homo sapiens Q04864 32911434
Intra
NFE2L2 Q16236 BTRC Homo sapiens Q9Y297 32911434
Intra
NFE2L2 Q16236 NFAT5 Homo sapiens O94916
FCS
32911434
Intra
NFE2L2 Q16236 NFAT5 Homo sapiens O94916 32911434
Intra
NFE2L2 Q16236 NFAT5 Homo sapiens O94916 32911434
Cross
NFE2L2 Q16236 Rara Mus musculus P11416 28777872
Intra
NFE2L2 Q16236 KPNA2 Homo sapiens P52292 32911434
Intra
NFE2L2 Q16236 KPNA2 Homo sapiens P52292 32911434
Intra
NFE2L2 Q16236 ARPC2 Homo sapiens O15144
FCS
32911434
Intra
NFE2L2 Q16236 ARPC2 Homo sapiens O15144 32911434
Intra
NFE2L2 Q16236 ARPC2 Homo sapiens O15144 32911434
Intra
NFE2L2 Q16236 ARPC2 Homo sapiens O15144 32911434
Intra
NFE2L2 Q16236 FBXW11 Homo sapiens Q9UKB1 32911434
Intra
NFE2L2 Q16236 TBP Homo sapiens P20226
FCS
32911434
Intra
NFE2L2 Q16236 TBP Homo sapiens P20226 32911434
Intra
NFE2L2 Q16236 TBP Homo sapiens P20226 32911434
Intra
NFE2L2 Q16236 TBP Homo sapiens P20226 32911434
Intra
NFE2L2 Q16236 EIF3J Homo sapiens O75822 32911434
Intra
NFE2L2 Q16236 EIF3J Homo sapiens O75822
FCS
32911434
Intra
NFE2L2 Q16236 EIF3J Homo sapiens O75822 32911434
Intra
NFE2L2 Q16236 EIF3J Homo sapiens O75822 32911434
Intra
NFE2L2 Q16236 FOSL2 Homo sapiens P15408
FCS
32911434
Intra
NFE2L2 Q16236 FOSL2 Homo sapiens P15408 32911434
Intra
NFE2L2 Q16236 FOSL2 Homo sapiens P15408 32911434
Intra
NFE2L2 Q16236 FOSL2 Homo sapiens P15408 32911434
Cross
NFE2L2 Q16236 Pml Mus musculus Q60953 28777872
Intra
NFE2L2 Q16236 ETV1 Homo sapiens P50549 32911434
Intra
NFE2L2 Q16236 ETV1 Homo sapiens P50549
FCS
32911434
Intra
NFE2L2 Q16236 ETV1 Homo sapiens P50549 32911434
Intra
NFE2L2 Q16236 GATA1 Homo sapiens P15976 32911434
Intra
NFE2L2 Q16236 GATA1 Homo sapiens P15976 32911434
Intra
NFE2L2 Q16236 KPNA4 Homo sapiens O00629
FCS
32911434
Intra
NFE2L2 Q16236 KPNA4 Homo sapiens O00629 32911434
Intra
NFE2L2 Q16236 KPNA4 Homo sapiens O00629 32911434
Intra
NFE2L2 Q16236 GRB2 Homo sapiens P62993 32911434
Intra
NFE2L2 Q16236 GRB2 Homo sapiens P62993 32911434
Intra
NFE2L2 Q16236 RARA Homo sapiens P10276 18048326
Intra
NFE2L2 Q16236 RARA Homo sapiens P10276 18048326
Intra
NFE2L2 Q16236 MAP2K6 Homo sapiens P52564 32911434
Intra
NFE2L2 Q16236 MAP2K6 Homo sapiens P52564 32911434
Intra
NFE2L2 Q16236 MAP2K6 Homo sapiens P52564
FCS
32911434
Intra
NFE2L2 Q16236 MAP2K6 Homo sapiens P52564 32911434
Intra
NFE2L2 Q16236 ATF4 Homo sapiens P18848 23661758
Intra
NFE2L2 Q16236 ATF4 Homo sapiens P18848 32911434
Intra
NFE2L2 Q16236 ATF4 Homo sapiens P18848
PLA
26700459
Intra
NFE2L2 Q16236 ATF4 Homo sapiens P18848 26700459
Intra
NFE2L2 Q16236 STAT3 Homo sapiens P40763 32911434
Intra
NFE2L2 Q16236 STAT3 Homo sapiens P40763 32911434
Intra
NFE2L2 Q16236 STAT3 Homo sapiens P40763 32911434
Intra
NFE2L2 Q16236 STAT3 Homo sapiens P40763
FCS
32911434
Intra
NFE2L2 Q16236 CASP7 Homo sapiens P55210 32911434
Intra
NFE2L2 Q16236 CASP7 Homo sapiens P55210 32911434
Intra
NFE2L2 Q16236 CREBZF Homo sapiens Q9NS37 32911434
Intra
NFE2L2 Q16236 CREBZF Homo sapiens Q9NS37
FCS
32911434
Intra
NFE2L2 Q16236 CREBZF Homo sapiens Q9NS37 32911434
Intra
NFE2L2 Q16236 CREBZF Homo sapiens Q9NS37 32911434
Intra
NFE2L2 Q16236 ARFIP2 Homo sapiens P53365 32911434
Intra
NFE2L2 Q16236 ARFIP2 Homo sapiens P53365 32911434
Intra
NFE2L2 Q16236 ETV4 Homo sapiens P43268
FCS
32911434
Intra
NFE2L2 Q16236 ETV4 Homo sapiens P43268 32911434
Intra
NFE2L2 Q16236 ETV4 Homo sapiens P43268 32911434
Intra
NFE2L2 Q16236 ETV4 Homo sapiens P43268 32911434
Intra
NFE2L2 Q16236 ATF3 Homo sapiens P18847 32911434
Intra
NFE2L2 Q16236 ATF3 Homo sapiens P18847 32911434
Intra
NFE2L2 Q16236 ATF3 Homo sapiens P18847
FCS
32911434
Intra
NFE2L2 Q16236 ATF3 Homo sapiens P18847 32911434
Intra
NFE2L2 Q16236 COPS7A Homo sapiens Q9UBW8 32911434
Intra
NFE2L2 Q16236 MAFG Homo sapiens O15525 34591642
Intra
NFE2L2 Q16236 MAFG Homo sapiens O15525 23661758
Intra
NFE2L2 Q16236 MAFG Homo sapiens O15525
FCS
32911434
Intra
NFE2L2 Q16236 MAFG Homo sapiens O15525 32911434
Intra
NFE2L2 Q16236 PMF1 Homo sapiens Q6P1K2 32911434
Intra
NFE2L2 Q16236 MAFF Homo sapiens Q9ULX9 34591642
Intra
NFE2L2 Q16236 MAFF Homo sapiens Q9ULX9 32911434
Intra
NFE2L2 Q16236 TNNT1 Homo sapiens P13805 25416956
Intra
NFE2L2 Q16236 TNNT1 Homo sapiens P13805 25416956
Intra
NFE2L2 Q16236 TNNT1 Homo sapiens P13805 31515488
Intra
NFE2L2 Q16236 ELK1 Homo sapiens P19419 32911434
Intra
NFE2L2 Q16236 ELK1 Homo sapiens P19419 32911434
Intra
NFE2L2 Q16236 RELA Homo sapiens Q04206 32911434
Intra
NFE2L2 Q16236 RELA Homo sapiens Q04206 32911434
Intra
NFE2L2 Q16236 RELA Homo sapiens Q04206
FCS
32911434
Intra
NFE2L2 Q16236 RELA Homo sapiens Q04206 32911434
Intra
NFE2L2 Q16236 CEBPG Homo sapiens P53567
FCS
32911434
Intra
NFE2L2 Q16236 CEBPG Homo sapiens P53567 32911434
Intra
NFE2L2 Q16236 CEBPG Homo sapiens P53567 32911434
Intra
NFE2L2 Q16236 CEBPG Homo sapiens P53567 32911434
Intra
NFE2L2 Q16236 TADA2A Homo sapiens O75478 32911434
Intra
NFE2L2 Q16236 TADA2A Homo sapiens O75478 32911434
Intra
NFE2L2 Q16236 DDIT3 Homo sapiens P35638
FCS
32911434
Intra
NFE2L2 Q16236 DDIT3 Homo sapiens P35638 32911434
Intra
NFE2L2 Q16236 DDIT3 Homo sapiens P35638 32911434
Intra
NFE2L2 Q16236 DDIT3 Homo sapiens P35638 32911434
Intra
NFE2L2 Q16236 NAA10 Homo sapiens P41227 36442525
Intra
NFE2L2 Q16236 NAA10 Homo sapiens P41227 36442525
Intra
NFE2L2 Q16236 WAC Homo sapiens Q9BTA9 25416956
Intra
NFE2L2 Q16236 KEAP1 Homo sapiens Q14145 16888629
Intra
NFE2L2 Q16236 KEAP1 Homo sapiens Q14145 16888629
Intra
NFE2L2 Q16236 JUN Homo sapiens P05412 32911434
Intra
NFE2L2 Q16236 LEF1 Homo sapiens Q9UJU2 32911434
Intra
NFE2L2 Q16236 LEF1 Homo sapiens Q9UJU2 32911434
Cross: Cross-species interaction Intra: Intraspecies interaction

NFE2L2 Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P80471 Phospho-Nrf2 (Ser40) Antibody (YA168) WB, ICC/IF, IHC-P, FC, IP Human
HY-P80841 Phospho-Nrf2 (Ser40) Antibody (YA169) WB, IHC-P Human
HY-P80841A Phospho-Nrf2 (Ser40) Antibody (YA169)(PBS only) WB, IHC-P Human
HY-P81051 Nrf2 Antibody(YA895) WB, IHC-P, ICC/IF, IP, ChIP Human, Mouse
HY-P81051A Nrf2 Antibody(YA895)(PBS only) WB, IHC-P, ICC/IF, IP, ChIP Human, Mouse
HY-P84609 Nrf2 Antibody (YA4306) IHC-P, ELISA Human
HY-P84609A Nrf2 Antibody (YA4306)(PBS only) IHC-P, ELISA Human
HY-P85818 Nrf2 Antibody (YA5510) WB, ICC/IF, ELISA Human, Mouse, Rat
HY-P86092 Nrf2 Antibody (YA5784) WB, IHC-P, ICC/IF, IP, ELISA Human, Mouse, Rat
HY-P86664 Nrf2 Antibody (YA6356) WB, IHC-P, IHC-F, IF-Tissue, FC, ICC/IF Human, Mouse, Rat

Related Diseases

Diseases Alias
Friedreich Ataxia
  • Friedreich Ataxia 1

  • FRDA

  • Friedreich Ataxia With Retained Reflexes

  • Frda1

  • Fa

  • Friedreich'S Ataxia

  • Hereditary Spinal Ataxia

  • Fa1

  • Friedreich'S Tabes

  • Hereditary Spinal Sclerosis

  • Spinocerebellar Ataxia, Friedreich

  • Friedreich Spinocerebellar Ataxia

  • Friedrich'S Ataxia

Ischemia
  • Acute Coronary Syndrome

Hypertension, Essential
  • Essential Hypertension

  • Hypertension

  • High Blood Pressure

  • Hypertension, Essential, Susceptibility To

  • Hypertensive Disease

  • Primary Hypertension

  • EHT

  • Hypertension, Salt-Sensitive Essential, Susceptibility To

  • Hyperpiesia

  • Idiopathic Hypertension

  • Hypertensive Disorder

  • Hypertension, Essential, Susceptibility To, 3

  • Hypertension, Essential 3

  • Hypertension, Essential, Salt-Sensitive

  • Hypertension, Essential, Susceptibility To, 6

  • Hypertension, Essential 6

  • Hypertension, Salt-Sensitive Essential

  • Hypertension, Susceptibility To

  • Hypertension, Essential, Susceptibility To, 4

  • Hypertension, Essential 4

  • Hypertension, Essential, Susceptibility To, 2

  • Hypertension, Essential 2

  • Hypertension, Essential, Susceptibility To, 1

  • Hypertension, Essential 1

  • Hypertension, Essential, Susceptibility To, 5

  • Hypertension, Essential 5

  • Htn

  • Vascular Hypertensive Disorder

  • Systemic Primary Arterial Hypertension

  • Hbp - [High Blood Pressure]

  • Systemic Arterial Hypertensive Disorder

  • Elevated Blood Pressure

  • Arterial Hypertension Nos

  • Hypertension Nos

  • Benign Hypertension

  • Systemic Arterial Hypertension

  • Systemic Hypertension

  • Artery Htn

  • Benign Htn

  • Vascular Htn

  • Vascular Hypertension

  • Cholesterol Hypertension

  • Cholesterol Htn

  • Idiopathic Htn

  • Malignant Hypertension

  • Malignant Htn

  • Raised Blood Pressure

  • Cardiovascular Hypertension

  • Primary Htn - [Hypertension]

  • High Arterial Tension

  • High Blood Pressure Disorder

  • Ht - [Hypertension]

  • Htn - [Hypertension]

  • Hypertensive Vascular Disease

  • Hypertensive Vascular Degeneration

Parkinson Disease 17
  • PARK17

  • Parkinson'S Disease 17

  • Autosomal Dominant Parkinson Disease 17

  • Parkinson Disease, Type 17

Lung Cancer Susceptibility 3
  • Lung Adenocarcinoma

  • Adenocarcinoma Of Lung

  • LNCR3

  • Adenocarcinoma Of Lung, Susceptibility To

  • Bronchogenic Lung Adenocarcinoma

  • Nonsmall Cell Adenocarcinoma

  • Adenocarcinoma Lung

  • Lung Adenocarcinomas

  • Non-Small Cell Adenocarcinoma

Diabetes Mellitus
  • Diabetes

Macular Degeneration, Age-Related, 1
  • Macular Degeneration

  • Age-Related Macular Degeneration

  • Macular Degeneration, Age-Related

  • Age Related Macular Degeneration

  • Age Related Macular Degeneration 1

  • ARMD1

  • Maculopathy, Age-Related, 1

  • Macular Degeneration, Age-Related, Reduced Risk Of

  • Age Related Maculopathy 1

  • Age Related Maculopathies

  • Age Related Maculopathy

  • Senile Macular Degeneration

  • Senile Macular Retinal Degeneration

  • Macular Degeneration Of Retina

  • Age-Related Maculopathy

  • Amd

  • Armd

  • Age-Related Maculopathy, Susceptibility To

  • Maculopathy Age-Related

  • Macular Degeneration, Age-Related, 1, Susceptibility To

  • Maculopathy, Age-Related

  • Macular Degeneration, Age-Related, Type 1

  • Macular Degeneration, Age-Related, 2

Eye Disease
  • Eye Diseases

  • Abnormality Of The Eye

  • Toxoplasma Oculopathy

Paraganglioma
  • Chemodectoma

  • Glomus Body Tumor

  • Paragangliomas

  • Carotid Body Paraganglioma

  • Extra-Adrenal Paraganglioma

Deficiency Anemia
  • Anemia

  • Deficiency Anemias

  • Anaemia

Malaria
  • Malaria, Susceptibility To

  • Malaria, Resistance To

  • Malaria, Cerebral

  • Cerebral Malaria

  • Malaria, Severe, Susceptibility To

  • Malaria, Severe, Resistance To

  • Malaria, Cerebral, Susceptibility To

  • Induced Malaria

  • Malaria, Vivax, Protection Against

  • Malaria, Severe

  • Malaria, Cerebral, Reduced Risk Of

  • Malaria, Protection Against

  • Resistance To Malaria Due To G6pd Deficiency

  • Malaria Due To G6pd Deficiency

  • Malarial Encephalitis

  • CM

  • Malaria Cerebral

  • Susceptibility To Malaria

  • Acute Pernicious Fever

  • Aestivo-Autumnal Fever

  • Aestivo Autumnal Malaria

  • Chagres Fever

  • Continued Malaria Fever

  • Estivo-Autumnal Fever

  • Estivo-Autumnal Malaria

  • Estivo-Autumnal Malarial Fever

  • Falciparum Fever

  • Malignant Tertian Fever

  • Malignant Tertian Malaria

  • Pernicious Intermittent Fever

  • Pernicious Malaria

  • Quotidian Malaria

  • Subtertian Fever

  • Subtertian Malaria Fever

  • Subtertian Malignant Tertian Malaria

  • Tropical Malaria

  • Algid Malaria

  • Bilious Haemoglobinuric Fever

  • Black Water Fever

  • Blackwater Fever

  • Malarial Blackwater Fever

  • Severe Malarial Falciparum

  • West African Fever

  • Malarial Haematinuria

  • Haemoglobinuric Fever

  • Haemoglobinuric Malaria

  • Severe Plasmodium Falciparum Malaria

  • Malarial Haemoglobinuria

  • Malarial Haematuria

  • Falciparum Malaria [Malignant Tertian]

  • Malaria Tropica

  • Malarial Shock

  • Chagres Virus Disease

  • Malignant Malaria

  • Mtm - [Malignant Tertian Malaria]

  • Tm -[Malignant Tertian Malaria]

  • Panama Fever

  • St - [Subtertian Malaria]

  • Malarial Quotidian

  • Benign Tertian Malaria

  • Tertian Ague

  • Vivax Fever

  • Plasmodium Vivax Malaria Nos

  • Btm - [Benign Tertian Malaria]

  • Bt - [Benign Tertian Malaria]

  • Vivax Malaria

  • Benign Tertian Vivax Malaria

  • Tertian Malaria

  • Quartan Malaria

  • Quartan Ague

  • Quartan Fever

  • Plasmodium Malariae Malaria Nos

  • Quartan Malarial

  • Malaria By Plasmodium Malariae

  • Malariae Malaria

  • Ovale Tertian Malaria

  • Plasmodium Ovale Fever

  • Malaria Fever By Plasmodium Ovale

  • Ovale Malaria

  • Malaria By Plasmodium Ovale

  • Malarial Ovale

  • Marsh Fever

  • Remittent Congestive Fever

  • Coastal Fever

  • Remittent Gastric Fever

  • Miasmatic Fever

  • Congestive Remittent Fever

  • Intermittent Fever

  • Jungle Fever

  • Paludism

  • Cameroon Fever

  • Ague

  • Corsican Fever

  • Intermittent Bilious Fever

  • Disease Due To Plasmodiidae

  • Malarial Fever

  • Plasmodiosis

  • Remittent Fever

  • Roman Fever

  • Malaria Fever Nos

  • Malaria Nos

  • Paludal Fever

  • Clinically Diagnosed Malaria

  • Clinically Diagnosed Malaria Without Parasitological Confirmation

  • Congestive Fever

  • Malarial Cachexia

  • Marsh Cachexia

  • Paludal Cachexia

  • Recurrent Malaria

  • Remittent Malaria

Colorectal Cancer
  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon

Acute Tympanitis
  • Acute Myringitis

Hepatocellular Carcinoma
  • Liver Cancer

  • Primary Liver Cancer

  • HCC

  • Hepatoma

  • Malignant Neoplasm Of Liver

  • Liver Neoplasms

  • Cancer, Hepatocellular

  • Liver Cell Carcinoma

  • Lcc

  • Hepatoblastoma, Somatic

  • Hepatic Cancer

  • Primary Malignant Neoplasm Of Liver

  • Rare Tumor Of Liver And Intrahepatic Biliary Tract

  • Hepatocellular Carcinoma, Somatic

  • Hepatocellular Carcinoma, Childhood Type, Somatic

  • Hepatocellular Cancer, Somatic

  • Ca Liver - Primary

  • Hepatic Neoplasm

  • Malignant Hepato-Biliary Neoplasm

  • Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

  • Malignant Neoplasm Of Liver, Primary

  • Malignant Tumor Of Liver

  • Neoplasm Of Liver

  • Non-Resectable Primary Hepatic Malignant Neoplasm

  • Resectable Malignant Neoplasm Of Liver

  • Resectable Malignant Neoplasm Of The Liver

  • Primary Liver Carcinoma

  • Primary Malignant Liver Neoplasm

  • Primary Cancer Of Liver

  • Primary Tumor Of The Liver

  • Rare Tumor Of Liver And Ibt

  • Hepatocellular Cancer

  • Neoplasm Of The Liver

  • Hepatomas

  • Liver Neoplasm

  • Liver Carcinoma

  • Liver And Intrahepatic Biliary Tract Carcinoma

  • Malignant Hepatobiliary Neoplasm

  • Adult Primary Hepatocellular Carcinoma

  • Hepatoblastoma

  • Carcinoma Of Liver

  • Malignant Liver Tumour

  • Malignant Hepatic Tumour

Hemochromatosis, Type 1
  • Hemochromatosis

  • Hemochromatosis Type 1

  • Hereditary Hemochromatosis

  • Hh

  • HFE1

  • Hfe Hemochromatosis, Modifier Of

  • Symptomatic Form Of Classic Hemochromatosis

  • Symptomatic Form Of Hemochromatosis Type 1

  • Symptomatic Form Of Hfe-Related Hereditary Hemochromatosis

  • Haemochromatosis

  • Iron Storage Disorder

  • Bronze Diabetes

  • Hlah

  • Hfe

  • Hemochromatosis, Hereditary

  • Diabetes Bronze

  • Classic Hemochromatosis

  • Hfe-Associated Hereditary Hemochromatosis

  • Hemochromatosis Classic

  • Bronzed Cirrhosis

  • Familial Hemochromatosis

  • Genetic Hemochromatosis

  • Hc

  • Hereditary Haemochromatosis

  • Pigmentary Cirrhosis

  • Primary Hemochromatosis

  • Troisier-Hanot-Chauffard Syndrome

  • Von Recklenhausen-Applebaum Disease

  • Hemochromatosis 1

  • Primary Hereditary Hemochromatosis

  • Bronze Cirrhosis

Diabetic Encephalopathy
Lung Cancer
  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Protection Against

  • Lung Cancer, Susceptibility To

  • Adenocarcinoma Of Lung, Somatic

  • Nonsmall Cell Lung Cancer

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma

Renal Cell Carcinoma, Papillary, 1
  • Papillary Renal Cell Carcinoma

  • Hereditary Papillary Renal Cell Carcinoma

  • Papillary Renal Cell Carcinoma, Sporadic

  • Papillary Renal Cell Adenocarcinoma

  • RCCP

  • RCCP1

  • Renal Cell Carcinoma, Papillary

  • Renal Cell Carcinoma, Papillary, 1, Familial And Somatic

  • Chromophil Carcinoma Of Kidney

  • Papillary Kidney Carcinoma

  • Sporadic Papillary Renal Cell Carcinoma

  • Chromophil Renal Cell Carcinoma

  • Papillary Renal Carcinoma, Malignant -

  • Papillary Renal Cell Carcinoma, Bilateral -

  • Papillary Renal Cell Carcinoma, Familial -

  • Papillary Renal Cell Carcinoma, Multiple -

  • Papillary Renal Cell Carcinoma, Sporadic -

  • Renal Adenocarcinoma

  • Chromophil Rcc

  • Hprcc

  • Renal Cell Carcinoma Papillary

  • Chromophilic Renal Cell Carcinoma

  • Prcc

  • Carcinoma, Renal Cell, Papillary, Type 1

  • Type 1 Papillary Renal Cell Carcinoma

  • Renal Cell Carcinoma

  • Hereditary Papillary Renal Carcinoma

Bladder Urothelial Carcinoma
  • Bladder Transitional Cell Carcinoma

  • Transitional Cell Carcinoma Of Bladder

  • Transitional Cell Carcinoma Of The Bladder

  • Urinary Bladder Urothelial Carcinoma

  • Urothelial Bladder Carcinoma

  • Carcinoma Transitional Cell Bladder

  • Tcc - [Transitional Cell Carcinoma] Of Bladder

Vagus Nerve Disease
  • Vagus Nerve Diseases

  • Disorder Of Pneumogastric [10th] Nerve

  • Disorder Of Vagal Nerve

  • Disorder Of Vagus Nerve

  • Vagus Nerve Disorder

  • Disorders Of The Tenth Cranial Nerve

  • Disorders Of 10th Cranial Nerve

  • Disorder Of Pneumogastric Nerve

Nervous System Disease
  • Abnormality Of The Nervous System

  • Nervous System Diseases

  • Nervous System Disorder

Stroke, Ischemic
  • Cerebral Infarction

  • Stroke

  • Ischemic Stroke

  • Cerebrovascular Accident

  • Cerebral Infarction, Susceptibility To

  • Stroke, Ischemic, Susceptibility To

  • Cerebral Infarct

  • Ischemic Stroke, Susceptibility To

  • Stroke, Susceptibility To

  • Cva - Cerebral Infarction

  • ISCHSTR

  • Ischemic Cerebrovascular Accident

Amyotrophic Lateral Sclerosis 1
  • Amyotrophic Lateral Sclerosis

  • ALS

  • Lou Gehrig Disease

  • Amyotrophic Lateral Sclerosis Type 1

  • Charcot Disease

  • ALS1

  • Amyotrophic Lateral Sclerosis, Susceptibility To

  • Fals

  • Lou Gehrig'S Disease

  • Mnd

  • Motor Neuron Disease

  • Familial Amyotrophic Lateral Sclerosis

  • Amyotrophic Lateral Sclerosis 1, Familial

  • Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

  • Motor Neuron Disease, Bulbar

  • Motor Neurone Disease

  • Amyotrophic Lateral Sclerosis With Dementia

  • Dementia With Amyotrophic Lateral Sclerosis

  • Motor Neuron Disease, Amyotrophic Lateral Sclerosis

  • Sclerosis, Lateral, Amyotrophic

  • Sclerosis, Lateral, Amyotrophic, Type 1

  • Amyotrophic Sclerosis

  • Als - [Amyotrophic Lateral Sclerosis]

  • Wasting Palsy

  • Amyotrophic Paralysis

  • Amyotrophy Lateral Sclerosis

  • Wasting Paralysis

  • Spinal Progressive Amyotrophy

  • Progressive Atrophic Paralysis

Prostate Cancer
  • Prostate Carcinoma

  • Prostate Cancer, Familial

  • Prostate Neoplasm

  • Prostate Cancer, Somatic

  • Prostate Cancer, Susceptibility To

  • Prostatic Cancer

  • Prostatic Neoplasms

  • Hereditary Prostate Cancer

  • Prostatic Neoplasm

  • Cancer Of Prostate

  • Carcinoma Of Prostate

  • Familial Prostate Cancer

  • Familial Prostate Carcinoma

  • Malignant Tumor Of Prostate

  • Malignant Neoplasm Of Prostate

  • Prostate Cancer, Familial, Susceptibility To

  • Malignant Tumor Of The Prostate

  • Ngp - New Growth Of Prostate

  • Tumor Of The Prostate

  • Prostate Cancer, Hereditary

  • Cancer Of The Prostate

  • Malignant Neoplasm Of The Prostate

  • Prostatic Carcinoma

  • PC

  • Prca

  • Cancer, Prostate

  • Malignant Prostatic Tumour

  • Malignant Tumour Of Prostate

  • Primary Prostate Cancer

  • Primary Malignant Neoplasm Of Prostate

  • Prostate Gland Cancer

Ureteral Obstruction
Mucositis
  • Inflammatory Disease Of Mucous Membrane

  • Gastrointestinal Mucositis

Squamous Cell Carcinoma
  • Epidermoid Carcinoma

  • Squamous Cell Cancer

  • Carcinoma, Squamous Cell

  • Malignant Squamous Cell Tumor

  • Squamous Carcinoma

  • Squamous Cell Epithelioma

  • Squamous Cell Skin Cancer

  • Carcinoma Squamous Cell

  • Neoplasms, Squamous Cell

  • Squamous Cell Carcinoma - Category

  • Malignant Squamous Cell Neoplasm

  • Squamous Cell Carcinoma Of Skin

Cystic Fibrosis
  • Mucoviscidosis

  • CF

  • Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

  • Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

  • Cystic Fibrosis Lung Disease, Modifier Of

  • Cystic Fibrosis Of Pancreas

  • Fibrocystic Disease Of Pancreas

  • Cf - [Cystic Fibrosis]

  • Cystic Fibrosis Nos

  • Fibrocystic Disease

  • Fibrocystic Disease Of The Pancreas

  • Mucoviscidosis Of Pancreas

  • Nonproliferative Fibrocystic Disease

  • Pancreatic Cystic Fibrosis

Leiomyomatosis
Non-Alcoholic Fatty Liver Disease
  • Fatty Liver

  • Non-Alcoholic Fatty Liver

  • Nafld

  • Nonalcoholic Fatty Liver Disease

  • Nonalcoholic Steatohepatitis

  • Steatosis

  • Nafl

  • Nash

  • Non-Alcoholic Steatohepatitis

  • Susceptibility To Nonalcoholic Fatty Liver Disease

  • Steatohepatitis

  • Fatty Degeneration

  • Non-Alcoholic Fatty Liver Disease Without Mention Of Non-Alcoholic Steatohepatitis

  • Nafld Without Nash

  • Nafld Without Mention Of Nash

Lung Squamous Cell Carcinoma
  • Squamous Cell Carcinoma Of Lung

  • Squamous Cell Lung Carcinoma

  • Epidermoid Cell Carcinoma Of The Lung

  • Squamous Cell Lung Cancer

Type 2 Diabetes Mellitus
  • Insulin Resistance

  • NIDDM

  • Diabetes Mellitus, Non-Insulin-Dependent

  • Type 2 Diabetes

  • T2D

  • Noninsulin-Dependent Diabetes Mellitus

  • Diabetes Mellitus, Type Ii

  • Maturity-Onset Diabetes

  • Insulin Resistance, Severe, Digenic

  • Diabetes Mellitus, Type 2

  • Diabetes Mellitus, Noninsulin-Dependent

  • Diabetes Mellitus, Noninsulin-Dependent, Association With

  • Diabetes Mellitus, Noninsulin-Dependent, Late Onset

  • Hypertension, Insulin Resistance-Related, Susceptibility To

  • Insulin Resistance, Susceptibility To

  • Non-Insulin-Dependent Diabetes Mellitus

  • Type Ii Diabetes Mellitus

  • Adult-Onset Diabetes Mellitus

  • Maturity-Onset Diabetes Mellitus

  • Diabetes Mellitus Type 2

  • Type Ii Diabetes

  • Type 2 Diabetes Mellitus, Susceptibility To

  • Diabetes, Type 2

  • Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To

  • Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To

  • Diabetes Mellitus, Type 2, Susceptibility To

  • Diabetes Mellitus, Noninsulin-Dependent, 2

  • Diabetes Mellitus, Type Ii, Susceptibility To

  • Hypertension, Insulin Resistance-Related

  • Adult-Onset Diabetes

  • Aodm

  • Diabetes Mellitus, Adult-Onset

  • Diabetes Mellitus Type Ii

  • Diabetes Mellitus Type 2, Susceptibility To

  • Diabetes, Type Ii, Susceptibility To

  • Diabetes Type 2

  • Diabetes Mellitus

  • Adult Onset Diabetes

  • Maturity Onset Diabetes

  • Nonketotic Diabetes

  • Non-Insulin Dependent Diabetes Mellitus

  • T2dm - [Type 2 Diabetes Mellitus]

  • Niddm - [Non Insulin Dependent Diabetes Mellitus]

  • Dm2

  • Dm Type Ii

  • Diabetic Type 2

  • Insulin Requiring Type 2 Diabetes

  • Noninsulin Dependent Diabetes

  • Non-Insulin-Dependent Diabetes Mellitus Without Complications

  • Diabetes Due To Insulin Secretory Defect

  • Diabetes Mellitus Due To Insulin Secretory Defect

  • Non-Insulin-Dependent Diabetes Of The Young

  • Senile Diabetes

  • Nonketotic Hyperglycaemia

  • Stable Diabetes

Peripheral Nervous System Disease
  • Peripheral Neuropathy

  • Peripheral Nerve Disease

  • Peripheral Nerve Disorders

  • Neuropathy, Peripheral

  • Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation

Pneumothorax
  • Pneumothorax Nos

  • Air Leak Nos

  • Pleural Air Leak Nos

Vascular Disease
  • Vascular Diseases

  • Aneurysm

  • Spinal Cord Ischemia

  • Spinal Cord Vascular Diseases

  • Vascular Tissue Disease

  • Vascular Anomaly

Renal Cell Carcinoma, Nonpapillary
  • Renal Cell Carcinoma

  • RCC

  • Nonpapillary Renal Cell Carcinoma

  • Clear Cell Renal Cell Carcinoma

  • Hypernephroma

  • Adenocarcinoma Of Kidney

  • Renal Carcinoma, Chromophobe, Somatic

  • Clear Cell Carcinoma Of Kidney

  • Clear-Cell Metastatic Renal Cell Carcinoma

  • Clear Cell Renal Carcinoma

  • Renal Cell Carcinoma, Somatic

  • Conventional Renal Cell Carcinoma

  • Conventional Renal Cell Carcinoma

  • Renal Clear Cell Carcinoma

  • Ccrcc

  • Hereditary Clear Cell Renal Cell Carcinoma

  • Carcinoma, Renal Cell

  • Renal Cell Carcinoma, Clear Cell, Somatic

  • Renal Cell Carcinoma, Clear Cell

  • Clear Cell Kidney Carcinoma

  • Clear Cell Rcc

  • Cystic-Multilocular Variant

  • Clear Cell Renal Cell Adenocarcinoma

  • Hereditary Clear Cell Renal Cell Adenocarcinoma

  • Common Renal Cell Carcinoma

  • Crcc

  • Renal Cell Carcinoma Non-Papillary

  • Carcinoma Renal Cell

  • Renal Cell Cancer

  • Carcinoma, Renal Cell, Nonpapillary

Cervical Cancer
  • Cervical Cancer, Somatic

  • Neoplasm Of Uterine Cervix

  • Cervix Cancer

  • Uterine Cervical Neoplasm

  • Cervical Neoplasm

  • Cervix Uteri Cancer

  • Tumor Of The Cervix Uteri

  • CERCA

  • Uterine Cervical Cancer

  • Neoplasms Cervical

  • Uterine Cervical Neoplasms

  • Cervical Cancers

  • Cancer, Cervical, Somatic

  • Malignant Tumor Of Cervix

  • Cervix Carcinoma

Cataract
  • Cataracts

  • Cat - [Cataract]

  • Cataract Form

  • Lens Opacity

  • Lens Opacities

Toxic Encephalopathy
  • Neurotoxicity

  • Neurotoxicity Syndromes

  • Neurotoxicity Syndrome

  • Encephalopathy, Toxic

Asthma
  • Chronic Obstructive Asthma

  • Asthma, Diminished Response To Antileukotriene Treatment In

  • Bronchial Hyperreactivity

  • Asthma, Susceptibility To

  • Asthma, Bronchial

  • Asthma, Protection Against

  • Asthma, Nocturnal, Susceptibility To

  • Nocturnal Asthma

  • Asthma-Related Traits

  • Asthma-Related Traits, Susceptibility To

  • Asthma, Nocturnal

  • Chronic Obstructive Asthma With Acute Exacerbation

  • Chronic Obstructive Asthma With Status Asthmaticus

  • Exercise Induced Asthma

  • Exercise-Induced Asthma

  • Bronchial Asthma

  • Asthma, Exercise-Induced

  • Idiosyncratic Asthma

  • Unspecified Asthma With Acute Exacerbation

  • Asthma, Unspecified, With Stated Status Asthmaticus

  • Status Asthmaticus Nos

  • Acute Severe Asthma

  • Acute Severe Bronchial Asthma

  • Status Asthma

  • Status Post Asthmaticus

Pheochromocytoma
  • Pheochromocytoma, Susceptibility To

  • Phaeochromocytoma

  • Adrenal Gland Chromaffin Paraganglioma

  • Adrenal Gland Chromaffinoma

  • Adrenal Gland Paraganglioma

  • Adrenal Gland Pheochromocytoma

  • Chromaffin Paraganglioma Of The Adrenal Gland

  • Intraadrenal Paraganglioma

  • PCC

  • Chromaffin Cell Tumor

  • Medullary Chromaffinoma

  • Medullary Paraganglioma

  • Pheochromoblastoma

  • Pheochromocytomas

  • Chromaffin Cell Neoplasm

  • Pheochromocytoma, Malignant

Squamous Cell Carcinoma, Head And Neck
  • Squamous Cell Carcinoma Of The Head And Neck

  • HNSCC

  • Head And Neck Squamous Cell Carcinoma

  • Head And Neck Cancer

  • Squamous Cell Carcinoma Of Lip

  • Squamous Cell Carcinoma, Head And Neck, Somatic

  • Carcinoma Of The Head And Neck

  • Squamous Cell Carcinomas Of Head And Neck

  • Scchn

  • Squamous Cell Carcinoma Of The Hypopharynx

  • Squamous Cell Carcinoma Of The Oropharynx

  • Squamous Cell Carcinoma Of Salivary Glands

  • Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses

  • Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses

  • Squamous Cell Carcinoma Of The Oral Cavity

  • Squamous Cell Carcinoma Of The Lip

  • Carcinoma, Squamous Cell Of Head And Neck

  • Lip Squamous Cell Carcinoma

  • Cancer, Head/Neck

  • Carcinoma, Squamous Cell, Head And Neck

  • Salivary Gland Squamous Cell Carcinoma

  • Cancer Of Head And Neck

  • Squamous Cell Carcinoma Of Oropharynx Nos

Immunodeficiency, Developmental Delay, And Hypohomocysteinemia
  • IMDDHH

Retinitis Pigmentosa
  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1

Osteoporosis
  • Postmenopausal Osteoporosis

  • Osteoporosis, Postmenopausal

  • Bone Mineral Density Quantitative Trait Locus

  • Bmnd

  • Osteoporosis, Involutional

  • Osteoporosis, Susceptibility To

  • Osteoporosis, Postmenopausal, Susceptibility

  • Bone Mineral Density Variation Qtl, Osteoporosis

  • OSTEOP

  • Involutional Osteoporosis

  • Senile Osteoporosis

  • Osteoporosis Postmenopausal

  • Bone Mineral Density, Quantitative Trait Locus

  • Osteoporosis, Senile

  • Idiopathic Osteoporosis

  • Bone Rarefaction Nos

  • Type 1 Osteoporosis

Neuroblastoma
  • Nb

  • Neuroblastoma, Susceptibility To

  • Neuroblastomas

  • Central Neuroblastoma

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Rattus norvegicus NFE2L2 RGD RGD:620360
Mus musculus NFE2L2 MGD MGI:108420
Felis catus NFE2L2 VGNC VGNC:68475
Canis familiaris NFE2L2 VGNC VGNC:43773
Bos taurus NFE2L2 VGNC VGNC:32036
Macaca mulatta NFE2L2 VGNC VGNC:75332
Others NFE2L2 NCBI