PPA-037
PPA-037 is an orally active, highly potent and selective inhibitor of cyclin-dependent kinase 12 (CDK12). PPA-037 induces the degradation of cyclin K (Cyclin K), enhancing antiproliferative effects on tumor cells. PPA-037 is promising for research of cancers.
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- CAS No.: 2883700-83-0
- Formule: C25H27N7
- Masse moléculaire:425.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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CDK12/Cyclin K |
Chemical Information
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CAS No. 2883700-83-0
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Masse moléculaire 425.53
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Formule C25H27N7
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SMILES
C1(CNC2=CC(N[C@H]3CCNC3)=NC4=C(C5CC5)C=NN24)=CC=C(C6=CC=CC=N6)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)