MRT-7612
MRT-7612 is a Cereblon-based Tyrosine kinase Molecular glue degrader. MRT-7612 significantly induces the degradation of HCK and LYN, while its degradation effect on LCK is weaker. MRT-7612 can be used for research on cancers such as chronic myeloid leukemia, autoimmune diseases, and chronic inflammatory diseases.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C25H24N4O4
- Molecular Weight:444.48
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Hck |
Lck |
Lyn |
Cereblon |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 444.48
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Formel C25H24N4O4
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SMILES
O=C(N1CC2(CCC3=C2C=CC=C3)C1)NC4=CC5=C(C(N(C(CC6)C(NC6=O)=O)C5)=O)C=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)