J208
J208 is a dual inhibitor for histone deacetylase (HDAC) and DNA methyltransferase (DNMT). J208 inhibits proliferation of cancer cells, as well as the migration/invasion of triple-negative breast cancer (TNBC) cells. J208 induces apoptosis, arrests the cell cycle at G0/G1 phase. J2008 activates the innate immune signalling pathway in TNBC, by inducing the expression of endogenous retroviruses (ERVs).
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- CAS No.: 2116468-11-0
- Formule: C20H24N6O4
- Masse moléculaire:412.44
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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HDAC1 |
Chemical Information
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CAS No. 2116468-11-0
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Masse moléculaire 412.44
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Formule C20H24N6O4
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SMILES
O=C1C=CN(C(N1)=O)CC2=CC=C(C=C2)C3=CN(N=N3)CCCCCCC(NO)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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