DS22
DS22 is a CDK12-cyclin K molecular glue degrader. DS22 promotes the formation of the DDB1-CDK12-cyclin K ternary complex, with an EC50 of 19 nM. DS22 can be used in research related to CDK12-mediated diseases, such as cancer.
For research use only. We do not sell to patients.
- CAS No.: 3068547-01-0
- Formula: C21H22Cl2N10O
- Molecular Weight:501.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
CDK12/Cyclin K 1316 nM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3068547-01-0
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Molecular Weight 501.37
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Formula C21H22Cl2N10O
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SMILES
CC[C@@H](NC1=NC(NCC2=NC3=CC(Cl)=C(Cl)C=C3N2)=C4C(N(C5=CN(C)N=C5)C=N4)=N1)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DS22 Related Classifications
HY-190189 Related Classifications
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