2. Gene
  3. GPX4 - glutathione peroxidase 4 Gene

GPX4 - glutathione peroxidase 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa

Also known as PHGPx

Gene ID: 399537 | Gene type: protein coding

About GPX4

GPX4 Products(1)

mRNA Protein Name
NM_214407.1 NP_999572.1 phospholipid hydroperoxide glutathione peroxidase precursor
Protein Preferred Names Protein Names

phospholipid hydroperoxide glutathione peroxidase

GPx-4

GSHPx-4

Phospholipid hydroperoxide glutathione peroxidase, mitochondrial

glutathione peroxidase 4 (phospholipid hydroperoxidase)

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-17355B Dexpramipexole Activator 99.56% Yes
Pre-clinical Phase
Bioactive Molecules (89)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100218A RSL3 Inhibitor 99.87% Unkown
HY-112654 GCN2iB Activator 99.83% Unkown
HY-100003 ML-210 Inhibitor 99.93% Unkown
HY-100002 ML162 Inhibitor 99.52% Unkown
HY-Y0669 Pipecolic acid Inhibitor 99.92% Unkown
HY-120912 Gingerenone A Activator 99.95% Unkown
HY-138153 JKE-1674 Inhibitor 99.54% Unkown
HY-141809 GPX4-IN-3 Inhibitor 99.83% Unkown
HY-W001083 3-Hydroxyphenylacetic acid Activator 99.77% Unkown
HY-N0070 Solasonine Inhibitor 99.19% Unkown
HY-115627 PKUMDL-LC-101-D04 Activator 99.83% Unkown
HY-P5381 gp91 ds-tat Activator 99.00% Unkown
HY-157068 icFSP1 99.94% Unkown
HY-171007 IRF1-IN-2 Activator 99.83% Unkown
HY-N0353 Curdione 99.80% Unkown
HY-W018161 Hexadecanedioic acid 98.0% Unkown
HY-155663 GPX4-IN-5 Inhibitor 99.73% Unkown
HY-175032 ATF3-IN-1 Agonist 96.30% Unkown
HY-161929 GPX4 activator 2 Activator 99.23% Unkown
HY-W014940 Ethylene glycol dimethacrylate Activator 99.52% Unkown
HY-149236 PROTAC GPX4 degrader-1 Degrader 99.35% Unkown
HY-138556 GPX4-IN-2 Control 98.32% Unkown
HY-P2833 Glutathione Peroxidase / Unkown
HY-Y0669S Pipecolic acid-d9 Inhibitor 99.9% Unkown
HY-W015600 2-Acetamidophenol Activator 99.73% Unkown
HY-149923 GPX4-IN-4 Inhibitor 98.94% Unkown
HY-153748 ML162-yne 99.06% Unkown
HY-161928 GPX4 activator 1 Activator 99.02% Unkown
HY-N8698 Picein Activator 99.98% Unkown
HY-167888 NPD4928 Inhibitor 99.48% Unkown
HY-157762 GPX4-IN-9 Inhibitor 99.18% Unkown
HY-139001 JKE-1716 Inhibitor 98.04% Unkown
HY-155664 GPX4-IN-6 Inhibitor 99.65% Unkown
HY-N3097 Pellitorine Agonist 99.84% Unkown
HY-174086 PROTAC GPX4 degrader-4 Degrader 99.68% Unkown
HY-175615 RSL3-NH2 Inhibitor / Unkown
HY-W015600S 2-Acetamidophenol-d3 99.48% Unkown
HY-151212 BCP-T.A ≥99.0% Unkown
HY-159990 GPX4-IN-15 Inhibitor 98.79% Unkown
HY-176557 NCI677397 Inhibitor / Unkown
HY-177204 DSPE-PEG2000-WLSEAGPVVTVRALRGTGSW Activator 95.0% Unkown
HY-176758 GPX4-IN-17 Inhibitor 98.1% Unkown
HY-169133 GDCNF-11 Degrader / Unkown
HY-155075 NC-R17 Inhibitor / Unkown
HY-181574 PDI-IN-5 Inhibitor / Unkown
HY-183791A Ferroptosis/apoptosis inducer-5 Inhibitor / Unkown
HY-W001083S1 3-Hydroxyphenylacetic acid-d5 Activator / Unkown
HY-181447 GPX4 (S)-9i Inhibitor / Unkown
HY-179294 POI ligand-2 Ligand / Unkown
HY-157788 ZX703 Degrader / Unkown
HY-176220 GPX4-AUTAC Degrader / Unkown
HY-179384 PROTAC FSP1 degrader 1 Activator / Unkown
HY-183554 Fa-Au Inhibitor / Unkown
HY-186143 KY0418 Inhibitor / Unkown
HY-174345 Ferroptosis inducer-8 Inhibitor / Unkown
HY-180245 STAT3-IN-51 Inhibitor / Unkown
HY-181598 GPX4 degrader-1 Degrader / Unkown
HY-182802 Ferroptosis inducer-15 Inhibitor / Unkown
HY-175633 ML210-ansaFc Inhibitor / Unkown
HY-168011 GPX4-IN-14 Inhibitor / Unkown
HY-155852 Lepadin H Inhibitor / Unkown
HY-175811 Ferroptosis inducer-10 Inhibitor / Unkown
HY-183544 Platinum(IV) Prodrug-1 Inhibitor / Unkown
HY-162717 GPX4-IN-11 Inhibitor / Unkown
HY-168879 GPX4-IN-16 Inhibitor / Unkown
HY-170509 Ferroptosis-IN-17 Activator / Unkown
HY-173408 Nur77 agonist-1 Inhibitor / Unkown
HY-179481 Ferroptosis inducer-13 Inhibitor / Unkown
HY-175614 RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide Inhibitor / Unkown
HY-175698 Ferroptosis inducer-9 Inhibitor / Unkown
HY-178115 MB-Buf Degrader / Unkown
HY-180199 GPX4-IN-21 Inhibitor / Unkown
HY-172675 DEL-I25 Activator / Unkown
HY-161972 ZX782 Degrader / Unkown
HY-178925 PROTAC GPX4 degrader-5 Degrader / Unkown
HY-168958 Ferroptosis-IN-18 Activator / Unkown
HY-175826 USP30-IN-20 Degrader / Unkown
HY-182072 GPX4-IN-23 Inhibitor / Unkown
HY-172761 AX-53802 Inducer / Unkown
HY-175041 GPX4-IN-18 Inhibitor / Unkown
HY-112654A GCN2iB acetate Activator / Unkown
HY-162106 PROTAC GPX4 degrader-2 Degrader / Unkown
HY-176271 MAO-B-IN-45 Activator / Unkown
HY-183294 GPX4-IN-24 Inhibitor / Unkown
HY-181656 GPX4 degrader-2 Inhibitor / Unkown
HY-138544 GPX4-IN-1 Inhibitor 99.76% Unkown
HY-175852 Ferroptosis inducer-11 Inhibitor / Unkown
HY-181953 STIM1-TFR1-IN-1 / Unkown
HY-149455 GPX4-IN-8 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens GPX4 NCBI NCBI:2879