DMTAP
Based on 1 Customer Validation
DMTAP is a cationic lipid that can be used for delivery of DNA, RNAi and drugs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.67%
- CAS 番号: 197974-74-6
- 分子式: C34H68ClNO4
- 分子量:590.36
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
![Trimethyl[2,3-(dioleyloxy)propyl]ammonium chloride](https://file.medchemexpress.com/product_pic/hy-w127644.gif)
生物活性
製品説明
化学情報
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CAS 番号 197974-74-6
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性状 Solid
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分子量 590.36
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分子式 C34H68ClNO4
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Color White to off-white
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SMILES
CCCCCCCCCCCCCC(OCC(OC(CCCCCCCCCCCCC)=O)C[N+](C)(C)C)=O.[Cl-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
体外:
Ethanol : 20 mg/mL (33.88 mM; Need ultrasonic)
DMSO : 2 mg/mL (3.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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RNA interference technology
RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing gene transcription or activating RNA degradation. This mechanism was discovered in plants in 1998 by Andrew Fire and Craig Mello. Today, this phenomenon can be observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals.
純度とドキュメンテーション
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データシート (268 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Gurtovenko AA, et al. Cationic DMPC/DMTAP lipid bilayers: molecular dynamics study. Biophys J. 2004 Jun;86(6):3461-72. [Content Brief]
[2]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811. [Content Brief]
[3]. Lajunen T, et al. Topical drug delivery to retinal pigment epithelium with microfluidizer produced small liposomes. Eur J Pharm Sci. 2014 Oct 1;62:23-32. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Ethanol | 1 mM | 1.6939 mL | 8.4694 mL | 16.9388 mL | 42.3470 mL |
| Ethanol | 5 mM | 0.3388 mL | 1.6939 mL | 3.3878 mL | 8.4694 mL |
| 10 mM | 0.1694 mL | 0.8469 mL | 1.6939 mL | 4.2347 mL | |
| 15 mM | 0.1129 mL | 0.5646 mL | 1.1293 mL | 2.8231 mL | |
| 20 mM | 0.0847 mL | 0.4235 mL | 0.8469 mL | 2.1174 mL | |
| 25 mM | 0.0678 mL | 0.3388 mL | 0.6776 mL | 1.6939 mL | |
| 30 mM | 0.0565 mL | 0.2823 mL | 0.5646 mL | 1.4116 mL |
DMTAP 関連分類
HY-112523A 関連分類
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