iRGD-CPT
iRGD-CPT is a conjugate of iRGD and camptothecin that is covalently coupled through a heterobifunctional linker. iRGD-CPT has anticancer activity in vitroandin vivo. iRGD-CPT can be used for the study of colon cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C75H100N18O27S3
- 分子量:1781.90
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | IC50 |
0.35 μM
Compound: iRGD-CPT
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Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
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[PMID: 38128233] |
| SW480 | IC50 |
0.32 μM
Compound: iRGD-CPT
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Cytotoxicity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
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[PMID: 38128233] |
化学情報
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分子量 1781.90
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分子式 C75H100N18O27S3
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SMILES
O=C(CC1SC[C@H](NC(C)=O)C(N[C@@H]2C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(NCC(N3CCC[C@H]3C(N[C@H](C(N[C@@H](CSSC2)C(O)=O)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N(CCC(NOCCOCCOCCCC(O[C@]4(CC)C(OCC5=C4C=C6N(CC7=CC8=CC=CC=C8N=C76)C5=O)=O)=O)=O)C1=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
iRGD-CPT 関連分類
HY-161095 関連分類
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