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製品番号: HY-134008

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Protoapigenone

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Protoapigenone is an antineoplastic agent isolated from ferns. Protoapigenone has significant inhibitory activity against Hep G2, Hep 3B, MCF-7, A549 and MDAMB-231, with IC₅₀s values of 1.60, 0.23, 0.78, 3.88 and 0.27 μg/mL respectively.

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純度: 99.84%
CAS 番号: 862884-32-0
分子式: C₁₅H₁₀O₆
分子量:286.24

保管条件:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Protoapigenone 構造式

CAS 番号: 862884-32-0

容量

価格（税別）

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数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Caspase アイソフォーム固有の製品をすべて表示 :

Bcl-2 Family アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	13.85 μM Compound: 1	Cytotoxicity against human A549 cells after 72 hrs by MTT colorimetric method Cytotoxicity against human A549 cells after 72 hrs by MTT colorimetric method	[PMID: 17622129]
HEK293	IC₅₀	6.79 μM Compound: 1	Cytotoxicity against human HEK293 cells assessed as cell proliferation after 24 hrs by MTT assay Cytotoxicity against human HEK293 cells assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]
Hep 3B2	IC₅₀	2.27 μM Compound: 1	Cytotoxicity against human Hep3B cells after 72 hrs by MTT colorimetric method Cytotoxicity against human Hep3B cells after 72 hrs by MTT colorimetric method	[PMID: 17622129]
HepG2	IC₅₀	7.77 μM Compound: 1	Antitumor activity against human HepG2 cells assessed as cell proliferation after 24 hrs by MTT assay Antitumor activity against human HepG2 cells assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]
HepG2	IC₅₀	8.11 μM Compound: 1	Cytotoxicity against human HepG2 cells after 72 hrs by MTT colorimetric method Cytotoxicity against human HepG2 cells after 72 hrs by MTT colorimetric method	[PMID: 17622129]
MCF7	IC₅₀	3.74 μM Compound: 1	Cytotoxicity against human MCF7 cells after 72 hrs by MTT colorimetric method Cytotoxicity against human MCF7 cells after 72 hrs by MTT colorimetric method	[PMID: 17622129]
MCF7	IC₅₀	5.5 μM Compound: 1	Antitumor activity against human MCF7 cells assessed as cell proliferation after 24 hrs by MTT assay Antitumor activity against human MCF7 cells assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]
MDA-MB-231	IC₅₀	1.43 μM Compound: 1	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT colorimetric method Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT colorimetric method	[PMID: 17622129]
MDA-MB-231	IC₅₀	1.7 μM Compound: 1	Antitumor activity against human MDA-MB-231 cells assessed as cell proliferation after 24 hrs by MTT assay Antitumor activity against human MDA-MB-231 cells assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]
PANC-1	IC₅₀	22.09 μM Compound: 1	Antitumor activity against human PANC1 cells assessed as cell proliferation after 24 hrs by MTT assay Antitumor activity against human PANC1 cells assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]
PBMC	IC₅₀	8.11 μM Compound: 1	Cytotoxicity against human PBMC assessed as cell proliferation after 24 hrs by MTT assay Cytotoxicity against human PBMC assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]
PC-3	IC₅₀	6.13 μM Compound: 1	Antitumor activity against human PC3 cells assessed as cell proliferation after 24 hrs by MTT assay Antitumor activity against human PC3 cells assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]
RPMI-8226	IC₅₀	3.93 μM Compound: 1	Antitumor activity against human RPMI8226 cells assessed as cell proliferation after 24 hrs by MTT assay Antitumor activity against human RPMI8226 cells assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]
SK-OV-3	IC₅₀	0.71 μM Compound: 1	Antitumor activity against human SKOV3 cells assessed as cell proliferation after 24 hrs by MTT assay Antitumor activity against human SKOV3 cells assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]
U-266	IC₅₀	7.66 μM Compound: 1	Antitumor activity against human U266 cells assessed as cell proliferation after 24 hrs by MTT assay Antitumor activity against human U266 cells assessed as cell proliferation after 24 hrs by MTT assay	[PMID: 21515048]

化学情報

CAS 番号 862884-32-0
性状 Solid
分子量 286.24
分子式 C₁₅H₁₀O₆
Color White to light yellow
SMILES

OC1=C2C(OC(C3(O)C=CC(C=C3)=O)=CC2=O)=CC(O)=C1
Structure Classification
- Flavonoids
- Flavones
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Lin A S, et al. New cytotoxic flavonoids from Thelypteris torresiana[J]. Planta medica, 2005, 71(09): 867-870.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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純度とドキュメンテーション
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Protoapigenone

Caspase アイソフォーム固有の製品をすべて表示

Bcl-2 Family アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Protoapigenone 関連分類

HY-134008 関連分類