iRGD-CPT
iRGD-CPT is a conjugate of iRGD and camptothecin that is covalently coupled through a heterobifunctional linker. iRGD-CPT has anticancer activity in vitroandin vivo. iRGD-CPT can be used for the study of colon cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C75H100N18O27S3
- 분자량:1781.90
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HT-29 | IC50 |
0.35 μM
Compound: iRGD-CPT
|
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
|
[PMID: 38128233] |
| SW480 | IC50 |
0.32 μM
Compound: iRGD-CPT
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Cytotoxicity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
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[PMID: 38128233] |
Chemical Information
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분자량 1781.90
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화학식 C75H100N18O27S3
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SMILES
O=C(CC1SC[C@H](NC(C)=O)C(N[C@@H]2C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(NCC(N3CCC[C@H]3C(N[C@H](C(N[C@@H](CSSC2)C(O)=O)=O)CC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N(CCC(NOCCOCCOCCCC(O[C@]4(CC)C(OCC5=C4C=C6N(CC7=CC8=CC=CC=C8N=C76)C5=O)=O)=O)=O)C1=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
iRGD-CPT Related Classifications
HY-161095 Related Classifications
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