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United States

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Cat. No.: HY-172964

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KIM-161

KIM-161 is a PIK3CA inhibitor. KIM-161 has significant antiproliferative activity with IC₅₀ values of 1.428 and 1.562 µM against PI3KCA mutant breast cancer MCF7 and T47D cells, respectively. KIM-161 induces apoptosis and cell cycle arrest by inhibiting the PI3K/AKT/mTOR signaling pathway and inducing ROS production. KIM-161 can be used to study breast cancer and its PI3KCA mutant subtypes.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 2559686-28-9
화학식: C₂₇H₂₅N₃O₃
분자량:439.51

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

KIM-161 Chemical Structure

CAS No.: 2559686-28-9

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

All PI3K Isoforms :

All Akt Isoforms :

All mTOR Isoforms :

Chemical Information

CAS No. 2559686-28-9
분자량 439.51
화학식 C₂₇H₂₅N₃O₃
SMILES

O=C(NCC1=CC=CC=C1)CC2=CC=C(N3C(/C(N=C3C)=C/C4=CC=C(OC)C=C4)=O)C=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. AlKharboush DF, et al. Exploring a kinase inhibitor targeting PI3KCA mutant cancer cells. J Biomol Struct Dyn. 2025 May 19:1-18. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
CAS No.:
Species:
Purity:
수량:

KIM-161

All PI3K Isoforms

All Akt Isoforms

All mTOR Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

KIM-161 Related Classifications

HY-172964 Related Classifications