Stictic acid
Based on 1 Customer Validation
Stictic acid is a secondary metabolite that can be isolated from the lichen Lobaria pulmonaria (L.) Hoffm. Stictic acid inhibits growth of human colon adenocarcinoma HT-29 cells (IC50: 29.29 μg/mL).
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- Purity: 98.5%
- CAS No.: 549-06-4
- 화학식: C19H14O9
- 분자량:386.31
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>10 μM
Compound: 1
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Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay
Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay
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[PMID: 24725159] |
| HeLa | IC50 |
>10 μM
Compound: 1
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Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay
Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay
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[PMID: 24725159] |
| Hepatocyte | IC50 |
≤13 μM
Compound: 3
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Cytotoxicity against rat hepatocytes assessed as induction intracellular LDH release incubated for 8 to 24 hrs
Cytotoxicity against rat hepatocytes assessed as induction intracellular LDH release incubated for 8 to 24 hrs
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[PMID: 33290062] |
| HL-60 | IC50 |
>10 μM
Compound: 1
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Cytotoxicity against human HL60 cells after 24 hrs by WST-1 assay
Cytotoxicity against human HL60 cells after 24 hrs by WST-1 assay
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[PMID: 24725159] |
| HL-60 | IC50 |
>10 μM
Compound: 1
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Cytotoxicity against human HL60 cells after 48 hrs by WST-1 assay
Cytotoxicity against human HL60 cells after 48 hrs by WST-1 assay
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[PMID: 24725159] |
| Vero | IC50 |
>150 μM
Compound: 1
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Cytotoxicity against African green monkey Vero cells after 24 hrs by Alamar Blue assay
Cytotoxicity against African green monkey Vero cells after 24 hrs by Alamar Blue assay
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[PMID: 24725159] |
| Vero | IC50 |
>150 μM
Compound: 1
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Cytotoxicity against African green monkey Vero cells after 48 hrs by Alamar Blue assay
Cytotoxicity against African green monkey Vero cells after 48 hrs by Alamar Blue assay
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[PMID: 24725159] |
Chemical Information
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CAS No. 549-06-4
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Appearance Solid
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분자량 386.31
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화학식 C19H14O9
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Color White to off-white
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SMILES
O=CC1=C(OC(C2=C(C(OC2O)=O)C(O)=C3C)=C3OC4=O)C4=C(C)C=C1OC
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Structure Classification
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Initial Source
Lobaria pulmonaria
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 11 mg/mL (28.47 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (275 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5886 mL | 12.9430 mL | 25.8859 mL | 64.7149 mL |
| 5 mM | 0.5177 mL | 2.5886 mL | 5.1772 mL | 12.9430 mL | |
| 10 mM | 0.2589 mL | 1.2943 mL | 2.5886 mL | 6.4715 mL | |
| 15 mM | 0.1726 mL | 0.8629 mL | 1.7257 mL | 4.3143 mL | |
| 20 mM | 0.1294 mL | 0.6471 mL | 1.2943 mL | 3.2357 mL | |
| 25 mM | 0.1035 mL | 0.5177 mL | 1.0354 mL | 2.5886 mL |
Stictic acid Related Classifications
HY-126779 Related Classifications
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