ZSQ836
ZSQ836 is an orally active dual covalent inhibitor of CDK12/CDK13, with an EC50 value of 32 nM against CDK12. ZSQ836 can induce apoptosis and exhibit anticancer activity in vivo. ZSQ836 can be used in the study of ovarian cancer.
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- CAS No.: 2634811-35-9
- 화학식: C27H28AsClN6OS2
- 분자량:627.06
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
EC50: 32 nM (CDK12)[1].
Chemical Information
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CAS No. 2634811-35-9
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분자량 627.06
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화학식 C27H28AsClN6OS2
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SMILES
ClC1=CN=C(N[C@H]2CN(CCC2)CC(NC3=CC=C([As]4SCCS4)C=C3)=O)N=C1C5=CNC6=CC=CC=C56
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)