4865 Results for "

Acid

" in MedChemExpress (MCE) Product Catalog:
Products (4865)

4865 Results for "Acid" in MCE Product Catalog:

21
21 Cited Publications
Cat. No.: HY-B0172
CAS No.: 434-13-9
Synonyms: 3α-Hydroxy-5β-cholanic Acid
Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist .
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20
20 Cited Publications
Cat. No.: HY-112754A
CAS No.: 132172-61-3
Purity:  99.91%
Synonyms: 1,2-Dioleoyl-3-trimethylammonium-propane chloride
Target:  

Liposome

Research Areas:  

Others

DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid .
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19
19 Cited Publications
Cat. No.: HY-108903A
CAS No.: 37326-33-3
Purity:  95.00%
Research Areas:  

Endocrinology

Hyaluronidase, Ovine testes is an endoglycosidase. Hyaluronidase, Ovine testes specifically degrades Hyaluronic acid (HY-B0633A) and Chondroitin sulfate (HY-B2162) by hydrolyzing β-glycosidic bonds in acidic mucopolysaccharides. Hyaluronidase, Ovine testes disperses follicular cells during fertilization by breaking down the hyaluronic acid-rich cumulus. Hyaluronidase, Ovine testes can be used in the study of fertility-related diseases .
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19
19 Cited Publications
Cat. No.: HY-109124
CAS No.: 1613267-49-4
Purity:  98.45%
Synonyms: VNRX-5133
Research Areas:  

Infection

Taniborbactam (VNRX-5133) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam is against Gram-negative bacteria .
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19
19 Cited Publications
Cat. No.: HY-109124A
CAS No.: 2244235-49-0
Purity:  99.97%
Synonyms: VNRX-5133 hydrochloride
Research Areas:  

Infection

Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam hydrochloride has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam hydrochloride is against Gram-negative bacteria .
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19
19 Cited Publications
Cat. No.: HY-107910
CAS No.: 37326-33-3
Synonyms: Hyaluronate 4-glycanohydrolase, Bovine testes; Hyaluronoglucosaminidase, Bovine testes
Target:  

NF-κB

Research Areas:  

Inflammation/Immunology Cancer

Hyaluronidase, Bovine testes (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is an endoglycosidase that depolymerizes Hyaluronic acid (HA) (HY-B0633A) by cleavage of glycosidic bonds. Hyaluronidase degrades HA and activates membrane receptors that trigger pathways converging in NF-κB activation. Hyaluronidase is employed in the research of granulomatous foreign body reactions, soft-tissue necrosis caused by vascular compromise and uncomplicated nodules, overcorrection, inflamed nodules or tissue ischemia associated with HA filler injection .
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18
18 Cited Publications
Cat. No.: HY-N0623
CAS No.: 73-22-3
Synonyms: Tryptophan; Tryptophane
L-Tryptophan (Tryptophan) is an orally active and essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3. L-Tryptophan can promote an increase in stemness and osteogenic ability of BMSCs in vitro and in vivo. L-Tryptophan inhibits cell proliferation and induced cell cycle arrest with high levels .
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17
17 Cited Publications
Cat. No.: HY-101106
CAS No.: 80306-38-3
Purity:  99.38%
Target:  

RAR/RXR

Research Areas:  

Neurological Disease Cancer

AR7 is an atypical RARA/RARα (retinoic acid receptor, alpha) antagonist. AR7 specifically activates chaperone-mediated-autophagy (CMA) activity without affecting macroautophagy .
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17
17 Cited Publications
Cat. No.: HY-N6733
CAS No.: 38966-21-1
Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering DNA polymerase activity. Aphidicolin is an antibiotic produced by mold Cephalosporium aphidicola, inhibits cellular deoxyribonucleic acid synthesis and the growth of herpes simplex virus. Aphidicolin exhibits anti-orthopoxvirus activity and potentiates apoptosis induced by arabinosyl nucleosides in a human promyelocytic leukemia cell line .
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16
16 Cited Publications
Cat. No.: HY-P0239A
HA Peptide (TFA) is a nine amino acids peptide derived from the human influenza hemagglutinin (HA). HA Peptide (TFA) is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry .
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15
15 Cited Publications
Cat. No.: HY-D0884
CAS No.: 27848-80-2
Synonyms: (S)-2-Hydroxypropanoic Acid lithium
L-Lactic acid lithium ((S)-2-Hydroxypropanoic acid lithium) is a buildiing block which can be used as a precursor for the production of the bioplastic polymer poly-lactic acid. L-Lactic acid lithium has antiproliferative activity .
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14
14 Cited Publications
Cat. No.: HY-18062
CAS No.: 58-14-0
Synonyms: Pirimecidan; Pirimetamin; RP 4753
Target:  

Antifolate Parasite

Research Areas:  

Infection Cancer

Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate .
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13
13 Cited Publications
Cat. No.: HY-W016715
CAS No.: 7048-04-6
L-Cysteine hydrochloride hydrate is an orally active and essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate regulates CBS/H2S pathway, inhibits NF-κB activation and insulin and ghrelin secretion. L-Cysteine hydrochloride hydrate reduces blood sugar, vascular inflammation markers and appetite. L-Cysteine hydrochloride hydrate induces kidney damage. L-Cysteine hydrochloride hydrate can be used in the study of neurological diseases and diabetes .
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13
13 Cited Publications
Cat. No.: HY-B0007
CAS No.: 1134-47-0
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Baclofen, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist with blood-brain barrier permeability. Baclofen mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen has high blood brain barrier penetrance. Baclofen has the potential for muscle spasticity research .
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13
13 Cited Publications
Cat. No.: HY-B0007C
CAS No.: 28311-31-1
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Baclofen hydrochloride, a lipophilic derivative of γ-aminobutyric acid (GABA), is an orally active, selective metabotropic GABAB receptor (GABABR) agonist. Baclofen hydrochloride mimics the action of GABA and produces slow presynaptic inhibition through the GABAB receptor. Baclofen hydrochloride has high blood brain barrier penetrance. Baclofen hydrochloride has the potential for muscle spasticity research .
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13
13 Cited Publications
Cat. No.: HY-Y0337A
CAS No.: 52-89-1
L-Cysteine hydrochloride is an orally active conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride suppresses ghrelin and reduces appetite in rodents. L-Cysteine hydrochloride inhibits Aspergillus flavus growth and AFB synthesis by disrupting cell structure and antioxidant system balance. L-Cysteine hydrochloride enhances relaxant responses of rat aortic rings to NO and reduces responses to endothelium-derived relaxing factor (EDRF) .
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13
13 Cited Publications
Cat. No.: HY-W016319
CAS No.: 138-15-8
Research Areas:  

Others

(S)-2-aminopentanedioic acid hydrochloride is a glutamic acid derivative .
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12
12 Cited Publications
Cat. No.: HY-113046
CAS No.: 134-35-0
Purity:  99.77%
Synonyms: 5-Methyl THF; 5-MTHF
5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases .
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12
12 Cited Publications
Cat. No.: HY-16911
CAS No.: 620175-39-5
Synonyms: API-1252; Debio 1452
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

AFN-1252 is an orally active and selective inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits exquisite and highly selective activity against Staphylococcus spp. AFN-1252 exhibits typical MIC90 values of ⩽0.015 μg/ml against diverse clinical isolates of S. aureus. AFN-1252 is efficacious in a mouse model of septicemia providing 100% protection from an otherwise lethal peritoneal infection of S. aureus Smith .
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12
12 Cited Publications
Cat. No.: HY-N0121
CAS No.: 607-80-7
Sesamin, abundant lignan found in sesame oil, is a potent and selective delta 5 desaturase inhibitor in polyunsaturated fatty acid biosynthesis. Sesamin exerts effective neuroprotection against cerbral ischemia .
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