Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1112 Results for "
Colon cancer
" in MedChemExpress (MCE) Product Catalog:
Products (1112)
1112 Results for "Colon cancer" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-N6263
CAS No.: 148707-39-5
Synonyms: AcEGCG; Peracetylated (-)-epigallocatechin-3-gallate
EGCG Octaacetate (AcEGCG) is a proagent of Green tea epigallocatechin-3-gallate (EGCG). EGCG Octaacetate decreases the proinflammatory mediator levels by down-regulating of PI3K/Akt/NFκB phosphorylation and p65 acetylation. EGCG octaacetate is the potential antibacterial compound for gram-positive bacteria (GPB) and gram-negative bacteria (GNB). EGCG Octaacetate exhibits antioxidant, anti-angiogenesis, anti-inflammatory and antitumor activities .
2
2 Cited Publications
PROTAC K-Ras Degrader-1 is a K-Ras PROTAC degrader. It binds to both K-Ras and the Cereblon E3 ubiquitin ligase, bringing K-Ras into proximity with the ligase, thereby achieving its degradation and inhibition. PROTAC K-Ras Degrader-1 can be used for research in various cancers .
2
2
2 Cited Publications
Cat. No.: HY-P71340
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: STUB1; CLL-Associated Antigen KW-8; STIP1 Homology And U-Box Containing Protein 1; Antigen NY-CO-7; CHIP; STIP1 Homology And U-Box Containing Protein 1, E3 Ubiquitin Protein Ligase; SDCCAG7; Heat Shock Protein A Binding Protein 2 (C-Terminal); HSPABP2; STIP1 Homology And U Box-Containing Protein 1; NY-CO-7; Serologically Defined Colon cancer Antigen 7; UBOX1; RING-Type E3 Ubiquitin Transferase; Carboxy Terminus Of Hsp70-Interacting Protein; SCAR16; RING-Type E3 Ubiquitin Transferase CHIP; SCA48; E3 Ubiquitin-Protein Ligase CHIP
Species:
Human
Source:
E. coli
1
1 Cited Publications
USL311 is an orally active CXCR4 inhibitor. USL311 blocks the activity of the CXCR4 receptor. USL311 is applicable to research related to various cancers including breast cancer, bladder cancer, colon cancer, rectal cancer, liver cancer and glioblastoma .
1
1 Cited Publications
Cat. No.: HY-W783415
CAS No.: 1424357-72-1
STARD3-IN-1 (Compound VS1) is a STARD3 inhibitor with an IC₅₀ of 35 μM. STARD3 is a protein that is overexpressed in various cancers and is involved in cholesterol transport. STARD3-IN-1 exhibits anti-proliferative activity in breast cancer and colon cancer cells, significantly weakening the clonogenic ability of cancer cells. STARD3-IN-1 increases the protein levels of FAK and pTyr397-FAK. STARD3-IN-1 can be used for research on breast cancer and colon cancer .
1
1 Cited Publications
Synonyms: Quercetin 3-rhamnoside (Standard)
1
1 Cited Publications
Target:
Research Areas:
BRD4 Inhibitor-20 is a potent orally active bromodomain protein 4 (BRD4) inhibitor. BRD4 Inhibitor-20 has inhibitory activity for BRD4 (BD1) and BRD4 (BD2) with IC50 values of 19 nM and 28 nM, respectively. BRD4 Inhibitor-20 also has anti-proliferation activities in cancer cell lines. BRD4 Inhibitor-20 can be used for the research of kinds of cancer, such as colon cancer .
1
1 Cited Publications
Target:
Research Areas:
JMJD6-IN-1 is a JMJD6 inhibitor, with an inhibition rate of 82% at 10 μM. JMJD6-IN-1 inhibits MCF-7 and HCC4006 cell proliferation with IC50 values of 19.2 μM and 25.2 μM. JMJD6-IN-1 inhibits JMJD6 demethylase activity. JMJD6-IN-1 can be used for the research of lung adenocarcinoma, prostate cancer, breast cancer, pancreatic cancer, colon cancer, oral squamous cell carcinoma, and glioblastoma .
1
1 Cited Publications
Cat. No.: HY-18604
CAS No.: 1629265-17-3
K-Ras G12C-IN-1 is an irreversible covalent KRAS G12C inhibitor. K-Ras G12C-IN-1 contains an electrophilic group that forms an irreversible covalent bond with Cys12 of mutant K-Ras. After covalent binding to Cys12, it locks Switch II in an inactive state and interferes with downstream Ras signaling. K-Ras G12C-IN-1 can be used in research related to pancreatic cancer, colon cancer, MYH-associated polyposis, colorectal cancer, and lung cancer .
1
1 Cited Publications
Cat. No.: HY-N6002
CAS No.: 475231-21-1
1
1 Cited Publications
Cat. No.: HY-149208
CAS No.: 2921948-27-6
HDAC-IN-53 is an orally active, and selective HDAC1-3 inhibitor with IC50 values of 47 nM, 125 nM, and 450 nM, respectively. HDAC-IN-53 does not inhibit class II HDACs (HDAC4, 5, 6, 7, 9; IC50>10 μM). HDAC-IN-53 induces caspase-dependent apoptosis. HDAC-IN-53 significantly inhibits the growth of human tumor xenografts in nude mice and murine tumor growth in immune-competent mice bearing MC38 colon cancer .
1
1 Cited Publications
Cat. No.: HY-N1854
CAS No.: 52117-69-8
Category:
Flavanonols Flavonoids Animals Other Diseases Scrophulariaceae Eremophila alternifolia Plants Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-P991447
1
1 Cited Publications
Cat. No.: HY-N6845
CAS No.: 19275-46-8
1
1 Cited Publications
Category:
1
7-Hydroxystaurosporine (UCN-01), a derivative of Staurosporine (HY-15141), is a selective protein kinase C (PKC) inhibitor with antitumor activity. 7-hydroxystaurosporine induces apoptosis and inhibits cell proliferation in colon carcinoma and leukemia cells, suppresses invasion and migration in glioblastoma cells. 7-Hydroxystaurosporine exhibits efficacy in breast cancer xenograft mouse models. 7-Hydroxystaurosporine can be used for colon carcinoma, breast cancer, glioblastoma and leukemia research .
1
Target:
Research Areas:
Sialyl Lewis A (SLeA) sodium is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A sodium promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A sodium shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A sodium can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .
1
1 Cited Publications
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
