2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Carbonic Anhydrase
  5. CA Ⅱ Isoform
  6. CA Ⅱ Inhibitor

CA Ⅱ Inhibitor

CA Ⅱ Inhibitors (15):

Cat. No. Product Name Effect Purity
  • HY-142849
    Carbonic anhydrase inhibitor 2
    		Inhibitor
    Carbonic anhydrase inhibitor 3 (compound 7c) is a carbonic anhydrase II inhibitor.
  • HY-152140
    hCAII-IN-8
    		Inhibitor
    hCAII-IN-8, an amide, is a highly selective carbonic anhydrase (CA) inhibitor with an IC50 value of 0.18 μM against hCA II.
  • HY-151472
    hCAIX/XII-IN-6
    		Inhibitor
    hCAIX/XII-IN-6 is an orally active carbonic anhydrase (CA) inhibitor.
  • HY-152141
    hCAII-IN-9
    		Inhibitor
    hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively.
  • HY-150977
    β-Glucuronidase/hCAII-IN-2
    		Inhibitor
    β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a potent β-glucuronidase and hCA II inhibitor with an IC50 of 670.7 μM and 21.77 μM, respectively.
  • HY-151578
    DPP IV/hCA II-IN-1
    		Inhibitor
    DPP IV/hCA II-IN-1 is a potent and selective dipeptidyl peptidase IV (DPP IV) and carbonic anhydrase (CA) inhibitor with an IC50 value of 0.049 μM for DPP IV and with Ki values of 0.0361, 0.0428, 0.0941, 0.1328, 0.2615, and 3.034 μM for CA II, CA VB, CA VA, CA IX, CA I, and CA IV, respectively.
  • HY-150976
    β-Glucuronidase/hCAII-IN-1
    		Inhibitor
    β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a potent β-glucuronidase and hCA II inhibitor with an IC50 of 440.1 μM and 4.91 μM, respectively.
  • HY-150570
    Carbonic anhydrase inhibitor 14
    		Inhibitor
    Carbonic anhydrase inhibitor 14 (Compound 8b) is a carbonic anhydrase (CA) inhibitor with Ki values of 1203, 99.7, 9.4 and 27.7 nM against hCA I, hCA II, hCA IX and hCA XII, respectively.
  • HY-B0588A
    Brinzolamide hydrochloride
    		Inhibitor
    Brinzolamide (AL-4862) hydrochloride is a selective carbonic anhydrase II inhibitor with an IC50 value of 3.2 nM.
  • HY-150975
    hCAII-IN-5
    		Inhibitor
    hCAII-IN-5 (compound 12h) is a potent and selective hCA II inhibitor with an IC50 value of 4.55 μM.
  • HY-146207
    HCAIX-IN-2
    		Inhibitor
    HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the Ki values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively.
  • HY-151495
    CAII-IN-3
    		Inhibitor
    CAII-IN-3 (compound 3h), a thiosemicarbazones derivatives, is a potent carbonic anhydrase-II (CA-II) inhibitor with an IC50 value of 13.4 µM.
  • HY-150973
    hCAII-IN-4
    		Inhibitor
    hCAII-IN-4 (Compound 12j) is a potent hCA II inhibitor with an IC50 of 7.78 μM.
  • HY-147353
    Phenylsulfamide
    		Inhibitor
    Phenylsulfamide (Compound 10) is a human carbonic anhydrase-II (hCA-II) inhibitor with a Kd of 45.50 μM and a Ki of 79.60 μM.
  • HY-151916
    Enpp/Carbonic anhydrase-IN-1
    		Inhibitor
    Enpp/Carbonic anhydrase-IN-1 (compound 1e) is a potent Enpp and carbonic anhydrase inhibitor with IC50s of 1.36, 1.35, 3.00, 0.88, 1.02 µM for NPP1, NPP2, NPP3, CA-II, CA-IX respectively.